BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

157 related articles for article (PubMed ID: 20869376)

  • 1. Design, synthesis and biological evaluation of estradiol-PEG-linked platinum(II) hybrid molecules: comparative molecular modeling study of three distinct families of hybrids.
    Provencher-Mandeville J; Debnath C; Mandal SK; Leblanc V; Parent S; Asselin E; Bérubé G
    Steroids; 2011 Jan; 76(1-2):94-103. PubMed ID: 20869376
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis of 17beta-estradiol-platinum(II) hybrid molecules showing cytotoxic activity on breast cancer cell lines.
    Provencher-Mandeville J; Descôteaux C; Mandal SK; Leblanc V; Asselin E; Bérubé G
    Bioorg Med Chem Lett; 2008 Apr; 18(7):2282-7. PubMed ID: 18356047
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Improved synthesis of unique estradiol-linked platinum(II) complexes showing potent cytocidal activity and affinity for the estrogen receptor alpha and beta.
    Descôteaux C; Leblanc V; Bélanger G; Parent S; Asselin E; Bérubé G
    Steroids; 2008 Oct; 73(11):1077-89. PubMed ID: 18572212
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis of 17beta-estradiol-linked platinum(II) complexes and their cytocidal activity on estrogen-dependent and -independent breast tumor cells.
    Perron V; Rabouin D; Asselin E; Parent S; C-Gaudreault R; Bérubé G
    Bioorg Chem; 2005 Feb; 33(1):1-15. PubMed ID: 15668178
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biological evaluation of novel estrogen-platinum(II) hybrid molecules on uterine and ovarian cancers-molecular modeling studies.
    Gagnon V; St-Germain ME; Descôteaux C; Provencher-Mandeville J; Parent S; Mandal SK; Asselin E; Bérubé G
    Bioorg Med Chem Lett; 2004 Dec; 14(23):5919-24. PubMed ID: 15501069
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis, antiproliferative activity and estrogen receptor α affinity of novel estradiol-linked platinum(II) complex analogs to carboplatin and oxaliplatin. Potential vector complexes to target estrogen-dependent tissues.
    Saha P; Descôteaux C; Brasseur K; Fortin S; Leblanc V; Parent S; Asselin E; Bérubé G
    Eur J Med Chem; 2012 Feb; 48():385-90. PubMed ID: 22209414
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and biological evaluation of estradiol-chlorambucil hybrids as anticancer agents.
    Gupta A; Saha P; Descôteaux C; Leblanc V; Asselin E; Bérubé G
    Bioorg Med Chem Lett; 2010 Mar; 20(5):1614-8. PubMed ID: 20137939
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis of unique 17beta-estradiol homo-dimers, estrogen receptors binding affinity evaluation and cytocidal activity on breast, intestinal and skin cancer cell lines.
    Bérubé G; Rabouin D; Perron V; N'Zemba B; Gaudreault RC; Parent S; Asselin E
    Steroids; 2006 Oct; 71(10):911-21. PubMed ID: 16914177
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, crystal structure, studies in solution and cytotoxicity of two new fluorescent platinum(II) compounds containing anthracene derivatives as a carrier ligand.
    Marqués-Gallego P; den Dulk H; Brouwer J; Kooijman H; Spek AL; Roubeau O; Teat SJ; Reedijk J
    Inorg Chem; 2008 Dec; 47(23):11171-9. PubMed ID: 18975941
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cobalt-alkyne complexes with imidazoline ligands as estrogenic carriers: synthesis and pharmacological investigations.
    Schlenk M; Ott I; Gust R
    J Med Chem; 2008 Nov; 51(22):7318-22. PubMed ID: 18942824
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis, cytocidal activity and estrogen receptor α affinity of doxorubicin conjugates at 16α-position of estrogen for site-specific treatment of estrogen receptor positive breast cancer.
    Saha P; Fortin S; Leblanc V; Parent S; Asselin É; Bérubé G
    Steroids; 2012 Sep; 77(11):1113-22. PubMed ID: 22801351
    [TBL] [Abstract][Full Text] [Related]  

  • 12. New platinum(II) complexes conjugated at position 7α of 17β-acetyl-testosterone as new combi-molecules against prostate cancer: design, synthesis, structure-activity relationships and biological evaluation.
    Fortin S; Brasseur K; Morin N; Asselin É; Bérubé G
    Eur J Med Chem; 2013 Oct; 68():433-43. PubMed ID: 23994871
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and cytotoxic activities of estrone and estradiol cis-dichloroplatinum(II) complexes.
    Kvasnica M; Rarova L; Oklestkova J; Budesinsky M; Kohout L
    Bioorg Med Chem; 2012 Dec; 20(24):6969-78. PubMed ID: 23142322
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selective estrogen receptor modulators in the ruthenocene series. Synthesis and biological behavior.
    Pigeon P; Top S; Vessières A; Huché M; Hillard EA; Salomon E; Jaouen G
    J Med Chem; 2005 Apr; 48(8):2814-21. PubMed ID: 15828819
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel platinum(II) complexes of 3-(aminomethyl)naphthoquinone Mannich bases: synthesis, crystal structure and cytotoxic activities.
    Neves AP; da Silva GB; Vargas MD; Pinheiro CB; Visentin Ldo C; Filho JD; Araújo AJ; Costa-Lotufo LV; Pessoa C; de Moraes MO
    Dalton Trans; 2010 Nov; 39(42):10203-16. PubMed ID: 20871881
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Potential new antitumor agents from an innovative combination of camphorato, a ramification of traditional Chinese medicine, with a platinum moiety.
    Wang L; Gou S; Chen Y; Liu Y
    Bioorg Med Chem Lett; 2005 Jul; 15(14):3417-22. PubMed ID: 15953727
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis, characterisation and in vitro cytotoxicity studies of a series of chiral platinum(II) complexes based on the 2-aminomethylpyrrolidine ligand: X-ray crystal structure of [PtCl2(R-dimepyrr)] (R-dimepyrr=N-dimethyl-2(R)-aminomethylpyrrolidine).
    Diakos CI; Zhang M; Beale PJ; Fenton RR; Hambley TW
    Eur J Med Chem; 2009 Jul; 44(7):2807-14. PubMed ID: 19185955
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dinuclear copper(I) complexes containing cyclodiphosphazane derivatives and pyridyl ligands: synthesis, structural studies, and antiproliferative activity toward human cervical and breast cancer cells.
    Balakrishna MS; Suresh D; Rai A; Mague JT; Panda D
    Inorg Chem; 2010 Oct; 49(19):8790-801. PubMed ID: 20812680
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Studies of the mechanism of action of platinum(II) complexes with potent cytotoxicity in human cancer cells.
    Krause-Heuer AM; Grünert R; Kühne S; Buczkowska M; Wheate NJ; Le Pevelen DD; Boag LR; Fisher DM; Kasparkova J; Malina J; Bednarski PJ; Brabec V; Aldrich-Wright JR
    J Med Chem; 2009 Sep; 52(17):5474-84. PubMed ID: 19658404
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis of 17beta-estradiol platinum(II) complexes: biological evaluation on breast cancer cell lines.
    Descôteaux C; Provencher-Mandeville J; Mathieu I; Perron V; Mandal SK; Asselin E; Bérubé G
    Bioorg Med Chem Lett; 2003 Nov; 13(22):3927-31. PubMed ID: 14592477
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.