221 related articles for article (PubMed ID: 20870413)
1. Synthesis and evaluation of benzoxazole derivatives as 5-lipoxygenase inhibitors.
Song H; Oh SR; Lee HK; Han G; Kim JH; Chang HW; Doh KE; Rhee HK; Choo HY
Bioorg Med Chem; 2010 Nov; 18(21):7580-5. PubMed ID: 20870413
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and biological evaluation of N-aryl-4-aryl-1,3-thiazole-2-amine derivatives as direct 5-lipoxygenase inhibitors.
Suh J; Yum EK; Cheon HG; Cho YS
Chem Biol Drug Des; 2012 Jul; 80(1):89-98. PubMed ID: 22404847
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and biological evaluation of 3-[4-(amino/methylsulfonyl)phenyl]methylene-indolin-2-one derivatives as novel COX-1/2 and 5-LOX inhibitors.
Lai Y; Ma L; Huang W; Yu X; Zhang Y; Ji H; Tian J
Bioorg Med Chem Lett; 2010 Dec; 20(24):7349-53. PubMed ID: 21055929
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis, and biological evaluation of prenylated chalcones as 5-LOX inhibitors.
Reddy NP; Aparoy P; Reddy TC; Achari C; Sridhar PR; Reddanna P
Bioorg Med Chem; 2010 Aug; 18(16):5807-15. PubMed ID: 20667741
[TBL] [Abstract][Full Text] [Related]
5. Structure based drug design, synthesis and evaluation of 4-(benzyloxy)-1-phenylbut-2-yn-1-ol derivatives as 5-lipoxygenase inhibitors.
Reddy NP; Chandramohan Reddy T; Aparoy P; Achari C; Sridhar PR; Reddanna P
Eur J Med Chem; 2012 Jan; 47(1):351-9. PubMed ID: 22118829
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and biological evaluation of a new class of acyl derivatives of 3-amino-1-phenyl-4,5-dihydro-1H-pyrazol-5-one as potential dual cyclooxygenase (COX-1 and COX-2) and human lipoxygenase (5-LOX) inhibitors.
Cusan C; Spalluto G; Prato M; Adams M; Bodensieck A; Bauer R; Tubaro A; Bernardi P; Da Ros T
Farmaco; 2005 Apr; 60(4):327-32. PubMed ID: 15848208
[TBL] [Abstract][Full Text] [Related]
7. Syntheses and characterization of nimesulide derivatives for dual enzyme inhibitors of both cyclooxygenase-1/2 and 5-lipoxygenase.
Li Y; Chen SH; Ou TM; Tan JH; Li D; Gu LQ; Huang ZS
Bioorg Med Chem; 2011 Mar; 19(6):2074-83. PubMed ID: 21349729
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and biological evaluation of indomethacin analogs possessing a N-difluoromethyl-1,2-dihydropyrid-2-one ring system: a search for novel cyclooxygenase and lipoxygenase inhibitors.
Chowdhury MA; Huang Z; Abdellatif KR; Dong Y; Yu G; Velázquez CA; Knaus EE
Bioorg Med Chem Lett; 2010 Oct; 20(19):5776-80. PubMed ID: 20727750
[TBL] [Abstract][Full Text] [Related]
9. A class of 5-benzylidene-2-phenylthiazolinones with high potency as direct 5-lipoxygenase inhibitors.
Hofmann B; Barzen S; Rödl CB; Kiehl A; Borig J; Zivković A; Stark H; Schneider G; Steinhilber D
J Med Chem; 2011 Mar; 54(6):1943-7. PubMed ID: 21341744
[TBL] [Abstract][Full Text] [Related]
10. Efficient synthesis and 5-LOX/COX-inhibitory activity of some 3-hydroxybenzo[b]thiophene-2-carboxylic acid derivatives.
Hansen FK; Khankischpur M; Tolaymat I; Mesaros R; Dannhardt G; Geffken D
Bioorg Med Chem Lett; 2012 Aug; 22(15):5031-4. PubMed ID: 22749420
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and biochemical evaluation of benzyl propargyl ethers as inhibitors of 5-lipoxygenase.
Barhate NB; Reddy MC; Reddy PS; Wakharkar RD; Reddanna P
Indian J Biochem Biophys; 2002 Aug; 39(4):264-73. PubMed ID: 22908417
[TBL] [Abstract][Full Text] [Related]
12. Pharmacological cross-reactivity between 5-lipoxygenase-activating protein, 5-lipoxygenase, and leukotriene C4 synthase.
Gupta N; Nicholson DW; Ford-Hutchinson AW
Can J Physiol Pharmacol; 1997; 75(10-11):1212-9. PubMed ID: 9431445
[TBL] [Abstract][Full Text] [Related]
13. Design, synthesis and biological evaluation of benzo[1.3.2]dithiazolium ylide 1,1-dioxide derivatives as potential dual cyclooxygenase-2/5-lipoxygenase inhibitors.
Tan CM; Chen GS; Chen CS; Chang PT; Chern JW
Bioorg Med Chem; 2011 Nov; 19(21):6316-28. PubMed ID: 21958737
[TBL] [Abstract][Full Text] [Related]
14. Syntheses and evaluation of novel isoliquiritigenin derivatives as potential dual inhibitors for amyloid-beta aggregation and 5-lipoxygenase.
Chen YP; Zhang ZY; Li YP; Li D; Huang SL; Gu LQ; Xu J; Huang ZS
Eur J Med Chem; 2013 Aug; 66():22-31. PubMed ID: 23786711
[TBL] [Abstract][Full Text] [Related]
15. Synthesis of new sulfonamides as lipoxygenase inhibitors.
Mustafa G; Khan IU; Ashraf M; Afzal I; Shahzad SA; Shafiq M
Bioorg Med Chem; 2012 Apr; 20(8):2535-9. PubMed ID: 22436389
[TBL] [Abstract][Full Text] [Related]
16. Development of 3,5-dinitrobenzoate-based 5-lipoxygenase inhibitors.
Shang E; Liu Y; Wu Y; Zhu W; He C; Lai L
Bioorg Med Chem; 2014 Apr; 22(8):2396-402. PubMed ID: 24685113
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and Biological Evaluation of N-Aryl-5-aryloxazol-2-amine Derivatives as 5-Lipoxygenase Inhibitors.
Suh JH; Yum EK; Cho YS
Chem Pharm Bull (Tokyo); 2015; 63(8):573-8. PubMed ID: 26040270
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and structure-activity relationship studies of novel dual inhibitors of soluble epoxide hydrolase and 5-lipoxygenase.
Meirer K; Rödl CB; Wisniewska JM; George S; Häfner AK; Buscató EL; Klingler FM; Hahn S; Berressem D; Wittmann SK; Steinhilber D; Hofmann B; Proschak E
J Med Chem; 2013 Feb; 56(4):1777-81. PubMed ID: 23356879
[TBL] [Abstract][Full Text] [Related]
19. Identification of 1, 4-Dihydrothieno [3', 2':5, 6]thiopyrano[4, 3-c] pyrazole derivatives as human 5-Lipo-oxygenase inhibitors.
Hu J; Zhu W; Meng H; Liu Y; Wang X; Hu C
Chem Biol Drug Des; 2014 Dec; 84(6):642-7. PubMed ID: 24889744
[TBL] [Abstract][Full Text] [Related]
20. Identification of 2-mercaptohexanoic acids as dual inhibitors of 5-lipoxygenase and microsomal prostaglandin E₂ synthase-1.
Greiner C; Zettl H; Koeberle A; Pergola C; Northoff H; Schubert-Zsilavecz M; Werz O
Bioorg Med Chem; 2011 Jun; 19(11):3394-401. PubMed ID: 21570310
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
