266 related articles for article (PubMed ID: 20870750)
1. Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer.
Pasternak A; Hernandez FJ; Rasmussen LM; Vester B; Wengel J
Nucleic Acids Res; 2011 Feb; 39(3):1155-64. PubMed ID: 20870750
[TBL] [Abstract][Full Text] [Related]
2. Thermodynamic and biological evaluation of a thrombin binding aptamer modified with several unlocked nucleic acid (UNA) monomers and a 2'-C-piperazino-UNA monomer.
Jensen TB; Henriksen JR; Rasmussen BE; Rasmussen LM; Andresen TL; Wengel J; Pasternak A
Bioorg Med Chem; 2011 Aug; 19(16):4739-45. PubMed ID: 21795054
[TBL] [Abstract][Full Text] [Related]
3. Novel isoguanine derivative of unlocked nucleic acid-Investigations of thermodynamics and biological potential of modified thrombin binding aptamer.
Kotkowiak W; Czapik T; Pasternak A
PLoS One; 2018; 13(5):e0197835. PubMed ID: 29795635
[TBL] [Abstract][Full Text] [Related]
4. Development of an Efficient G-Quadruplex-Stabilised Thrombin-Binding Aptamer Containing a Three-Carbon Spacer Molecule.
Aaldering LJ; Poongavanam V; Langkjaer N; Murugan NA; Jørgensen PT; Wengel J; Veedu RN
Chembiochem; 2017 Apr; 18(8):755-763. PubMed ID: 28150905
[TBL] [Abstract][Full Text] [Related]
5. Thermodynamic, Anticoagulant, and Antiproliferative Properties of Thrombin Binding Aptamer Containing Novel UNA Derivative.
Kotkowiak W; Lisowiec-Wachnicka J; Grynda J; Kierzek R; Wengel J; Pasternak A
Mol Ther Nucleic Acids; 2018 Mar; 10():304-316. PubMed ID: 29499943
[TBL] [Abstract][Full Text] [Related]
6. Improved RE31 Analogues Containing Modified Nucleic Acid Monomers: Thermodynamic, Structural, and Biological Effects.
Kotkowiak W; Wengel J; Scotton CJ; Pasternak A
J Med Chem; 2019 Mar; 62(5):2499-2507. PubMed ID: 30735377
[TBL] [Abstract][Full Text] [Related]
7. Structural and Binding Effects of Chemical Modifications on Thrombin Binding Aptamer (TBA).
Valsangkar V; Vangaveti S; Lee GW; Fahssi WM; Awan WS; Huang Y; Chen AA; Sheng J
Molecules; 2021 Jul; 26(15):. PubMed ID: 34361773
[TBL] [Abstract][Full Text] [Related]
8. Unlocking G-quadruplex: Effect of unlocked nucleic acid on G-quadruplex stability.
Agarwal T; Kumar S; Maiti S
Biochimie; 2011 Oct; 93(10):1694-700. PubMed ID: 21718749
[TBL] [Abstract][Full Text] [Related]
9. Structural and mechanistic insights into modified G-quadruplex thrombin-binding DNA aptamers.
Sun L; Xie X; Weng W; Jin H
Biochem Biophys Res Commun; 2019 Jun; 513(3):753-759. PubMed ID: 30992128
[TBL] [Abstract][Full Text] [Related]
10. Anomeric DNA quadruplexes.
Kolganova NA; Varizhuk AM; Novikov RA; Florentiev VL; Pozmogova GE; Borisova OF; Shchyolkina AK; Smirnov IP; Kaluzhny DN; Timofeev EN
Artif DNA PNA XNA; 2014; 5(2):e28422. PubMed ID: 25483931
[TBL] [Abstract][Full Text] [Related]
11. The effect on quadruplex stability of North-nucleoside derivatives in the loops of the thrombin-binding aptamer.
Aviñó A; Mazzini S; Ferreira R; Gargallo R; Marquez VE; Eritja R
Bioorg Med Chem; 2012 Jul; 20(14):4186-93. PubMed ID: 22727781
[TBL] [Abstract][Full Text] [Related]
12. Improving Thermodynamic Stability and Anticoagulant Activity of a Thrombin Binding Aptamer by Incorporation of 8-trifluoromethyl-2'-deoxyguanosine.
Bao HL; Ishizuka T; Yamashita A; Furukoji E; Asada Y; Xu Y
J Med Chem; 2021 Jan; 64(1):711-718. PubMed ID: 33289557
[TBL] [Abstract][Full Text] [Related]
13. Improving the Biological Properties of Thrombin-Binding Aptamer by Incorporation of 8-Bromo-2'-Deoxyguanosine and 2'-Substituted RNA Analogues.
Virgilio A; Benigno D; Aliberti C; Vellecco V; Bucci M; Esposito V; Galeone A
Int J Mol Sci; 2023 Oct; 24(21):. PubMed ID: 37958511
[TBL] [Abstract][Full Text] [Related]
14. Synthesis, characterization and in vitro activity of thrombin-binding DNA aptamers with triazole internucleotide linkages.
Varizhuk AM; Tsvetkov VB; Tatarinova ON; Kaluzhny DN; Florentiev VL; Timofeev EN; Shchyolkina AK; Borisova OF; Smirnov IP; Grokhovsky SL; Aseychev AV; Pozmogova GE
Eur J Med Chem; 2013 Sep; 67():90-7. PubMed ID: 23850569
[TBL] [Abstract][Full Text] [Related]
15. Unfolding and conformational variations of thrombin-binding DNA aptamers: synthesis, circular dichroism and molecular dynamics simulations.
Sun L; Jin H; Zhao X; Liu Z; Guan Y; Yang Z; Zhang L; Zhang L
ChemMedChem; 2014 May; 9(5):993-1001. PubMed ID: 24715713
[TBL] [Abstract][Full Text] [Related]
16. Favorable 2'-substitution in the loop region of a thrombin-binding DNA aptamer.
Awachat R; Wagh AA; Aher M; Fernandes M; Kumar VA
Bioorg Med Chem Lett; 2018 Jun; 28(10):1765-1768. PubMed ID: 29678465
[TBL] [Abstract][Full Text] [Related]
17. Studies of the binding mechanism between aptamers and thrombin by circular dichroism, surface plasmon resonance and isothermal titration calorimetry.
Lin PH; Chen RH; Lee CH; Chang Y; Chen CS; Chen WY
Colloids Surf B Biointerfaces; 2011 Dec; 88(2):552-8. PubMed ID: 21885262
[TBL] [Abstract][Full Text] [Related]
18. Conformation and thermostability of oligonucleotide d(GGTTGGTGTGGTTGG) containing thiophosphoryl internucleotide bonds at different positions.
Zaitseva M; Kaluzhny D; Shchyolkina A; Borisova O; Smirnov I; Pozmogova G
Biophys Chem; 2010 Jan; 146(1):1-6. PubMed ID: 19846249
[TBL] [Abstract][Full Text] [Related]
19. Cation Coordination Alters the Conformation of a Thrombin-Binding G-Quadruplex DNA Aptamer That Affects Inhibition of Thrombin.
Zavyalova E; Tagiltsev G; Reshetnikov R; Arutyunyan A; Kopylov A
Nucleic Acid Ther; 2016 Oct; 26(5):299-308. PubMed ID: 27159247
[TBL] [Abstract][Full Text] [Related]
20. Thrombin binding aptamer, more than a simple aptamer: chemically modified derivatives and biomedical applications.
Avino A; Fabrega C; Tintore M; Eritja R
Curr Pharm Des; 2012; 18(14):2036-47. PubMed ID: 22376107
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]