BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

241 related articles for article (PubMed ID: 20876458)

  • 1. Regulation of platelet myosin light chain (MYL9) by RUNX1: implications for thrombocytopenia and platelet dysfunction in RUNX1 haplodeficiency.
    Jalagadugula G; Mao G; Kaur G; Goldfinger LE; Dhanasekaran DN; Rao AK
    Blood; 2010 Dec; 116(26):6037-45. PubMed ID: 20876458
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dysregulation of PLDN (pallidin) is a mechanism for platelet dense granule deficiency in RUNX1 haplodeficiency.
    Mao GF; Goldfinger LE; Fan DC; Lambert MP; Jalagadugula G; Freishtat R; Rao AK
    J Thromb Haemost; 2017 Apr; 15(4):792-801. PubMed ID: 28075530
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Decreased platelet expression of myosin regulatory light chain polypeptide (MYL9) and other genes with platelet dysfunction and CBFA2/RUNX1 mutation: insights from platelet expression profiling.
    Sun L; Gorospe JR; Hoffman EP; Rao AK
    J Thromb Haemost; 2007 Jan; 5(1):146-54. PubMed ID: 17059412
    [TBL] [Abstract][Full Text] [Related]  

  • 4. RUNX1/core binding factor A2 regulates platelet 12-lipoxygenase gene (ALOX12): studies in human RUNX1 haplodeficiency.
    Kaur G; Jalagadugula G; Mao G; Rao AK
    Blood; 2010 Apr; 115(15):3128-35. PubMed ID: 20181616
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Platelet protein kinase C-theta deficiency with human RUNX1 mutation: PRKCQ is a transcriptional target of RUNX1.
    Jalagadugula G; Mao G; Kaur G; Dhanasekaran DN; Rao AK
    Arterioscler Thromb Vasc Biol; 2011 Apr; 31(4):921-7. PubMed ID: 21252065
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dysmegakaryopoiesis of FPD/AML pedigrees with constitutional RUNX1 mutations is linked to myosin II deregulated expression.
    Bluteau D; Glembotsky AC; Raimbault A; Balayn N; Gilles L; Rameau P; Nurden P; Alessi MC; Debili N; Vainchenker W; Heller PG; Favier R; Raslova H
    Blood; 2012 Sep; 120(13):2708-18. PubMed ID: 22898599
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Downregulation of TREM-like transcript-1 and collagen receptor α2 subunit, two novel RUNX1-targets, contributes to platelet dysfunction in familial platelet disorder with predisposition to acute myelogenous leukemia.
    Glembotsky AC; Sliwa D; Bluteau D; Balayn N; Marin Oyarzún CP; Raimbault A; Bordas M; Droin N; Pirozhkova I; Washington V; Goette NP; Marta RF; Favier R; Raslova H; Heller PG
    Haematologica; 2019 Jun; 104(6):1244-1255. PubMed ID: 30545930
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanisms underlying platelet function defect in a pedigree with familial platelet disorder with a predisposition to acute myelogenous leukemia: potential role for candidate RUNX1 targets.
    Glembotsky AC; Bluteau D; Espasandin YR; Goette NP; Marta RF; Marin Oyarzun CP; Korin L; Lev PR; Laguens RP; Molinas FC; Raslova H; Heller PG
    J Thromb Haemost; 2014 May; 12(5):761-72. PubMed ID: 24606315
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Defective RAB1B-related megakaryocytic ER-to-Golgi transport in RUNX1 haplodeficiency: impact on von Willebrand factor.
    Jalagadugula G; Goldfinger LE; Mao G; Lambert MP; Rao AK
    Blood Adv; 2018 Apr; 2(7):797-806. PubMed ID: 29632235
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanism of platelet factor 4 (PF4) deficiency with RUNX1 haplodeficiency: RUNX1 is a transcriptional regulator of PF4.
    Aneja K; Jalagadugula G; Mao G; Singh A; Rao AK
    J Thromb Haemost; 2011 Feb; 9(2):383-91. PubMed ID: 21129147
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Defective acid hydrolase secretion in RUNX1 haplodeficiency: Evidence for a global platelet secretory defect.
    Rao AK; Poncz M
    Haemophilia; 2017 Sep; 23(5):784-792. PubMed ID: 28662545
    [TBL] [Abstract][Full Text] [Related]  

  • 12. RUNX1, but not its familial platelet disorder mutants, synergistically activates PF4 gene expression in combination with ETS family proteins.
    Okada Y; Watanabe M; Nakai T; Kamikawa Y; Shimizu M; Fukuhara Y; Yonekura M; Matsuura E; Hoshika Y; Nagai R; Aird WC; Doi T
    J Thromb Haemost; 2013 Sep; 11(9):1742-50. PubMed ID: 23848403
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MYH10 protein expression in platelets as a biomarker of RUNX1 and FLI1 alterations.
    Antony-Debré I; Bluteau D; Itzykson R; Baccini V; Renneville A; Boehlen F; Morabito M; Droin N; Deswarte C; Chang Y; Leverger G; Solary E; Vainchenker W; Favier R; Raslova H
    Blood; 2012 Sep; 120(13):2719-22. PubMed ID: 22677128
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of the Platelet Phenotype Caused by a Germline RUNX1 Variant in a CRISPR/Cas9-Generated Murine Model.
    Marín-Quílez A; García-Tuñón I; Fernández-Infante C; Hernández-Cano L; Palma-Barqueros V; Vuelta E; Sánchez-Martín M; González-Porras JR; Guerrero C; Benito R; Rivera J; Hernández-Rivas JM; Bastida JM
    Thromb Haemost; 2021 Sep; 121(9):1193-1205. PubMed ID: 33626581
    [No Abstract]   [Full Text] [Related]  

  • 15. Low Mpl receptor expression in a pedigree with familial platelet disorder with predisposition to acute myelogenous leukemia and a novel AML1 mutation.
    Heller PG; Glembotsky AC; Gandhi MJ; Cummings CL; Pirola CJ; Marta RF; Kornblihtt LI; Drachman JG; Molinas FC
    Blood; 2005 Jun; 105(12):4664-70. PubMed ID: 15741216
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MAL/SRF complex is involved in platelet formation and megakaryocyte migration by regulating MYL9 (MLC2) and MMP9.
    Gilles L; Bluteau D; Boukour S; Chang Y; Zhang Y; Robert T; Dessen P; Debili N; Bernard OA; Vainchenker W; Raslova H
    Blood; 2009 Nov; 114(19):4221-32. PubMed ID: 19724058
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Altered platelet-megakaryocyte endocytosis and trafficking of albumin and fibrinogen in RUNX1 haplodeficiency.
    Del Carpio-Cano F; Mao G; Goldfinger LE; Wurtzel J; Guan L; Alam MA; Lee K; Poncz M; Rao AK
    Blood Adv; 2024 Apr; 8(7):1699-1714. PubMed ID: 38330198
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transcription Factor RUNX1 Regulates Platelet
    Mao G; Songdej N; Voora D; Goldfinger LE; Del Carpio-Cano FE; Myers RA; Rao AK
    Circulation; 2017 Sep; 136(10):927-939. PubMed ID: 28676520
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Level of RUNX1 activity is critical for leukemic predisposition but not for thrombocytopenia.
    Antony-Debré I; Manchev VT; Balayn N; Bluteau D; Tomowiak C; Legrand C; Langlois T; Bawa O; Tosca L; Tachdjian G; Leheup B; Debili N; Plo I; Mills JA; French DL; Weiss MJ; Solary E; Favier R; Vainchenker W; Raslova H
    Blood; 2015 Feb; 125(6):930-40. PubMed ID: 25490895
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular phenotype and bleeding risks of an inherited platelet disorder in a family with a RUNX1 frameshift mutation.
    Badin MS; Iyer JK; Chong M; Graf L; Rivard GE; Waye JS; Paterson AD; Pare G; Hayward CPM
    Haemophilia; 2017 May; 23(3):e204-e213. PubMed ID: 28181366
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.