88 related articles for article (PubMed ID: 20880612)
1. Novel structural insights for drug design of selective 5-HT(2C) inverse agonists from a ligand-biased receptor model.
Renault N; Gohier A; Chavatte P; Farce A
Eur J Med Chem; 2010 Nov; 45(11):5086-99. PubMed ID: 20880612
[TBL] [Abstract][Full Text] [Related]
2. Identification of novel serotonin 2C receptor ligands by sequential virtual screening.
Ahmed A; Choo H; Cho YS; Park WK; Pae AN
Bioorg Med Chem; 2009 Jul; 17(13):4559-68. PubMed ID: 19464901
[TBL] [Abstract][Full Text] [Related]
3. 5-HT₂c receptor selectivity and structure-activity relationship of N-methyl-N-(1-methylpiperidin-4-yl)benzenesulfonamide analogs.
Jang JW; Baek JS; Choi GD; Park WK; Cho YS; Baek DJ; Pae AN
Bioorg Med Chem Lett; 2012 Jan; 22(1):347-52. PubMed ID: 22153942
[TBL] [Abstract][Full Text] [Related]
4. Current status of inverse agonism at serotonin2A (5-HT2A) and 5-HT2C receptors.
Aloyo VJ; Berg KA; Spampinato U; Clarke WP; Harvey JA
Pharmacol Ther; 2009 Feb; 121(2):160-73. PubMed ID: 19109993
[TBL] [Abstract][Full Text] [Related]
5. Characterizing the effects of 5-HT(2C) receptor ligands on motor activity and feeding behaviour in 5-HT(2C) receptor knockout mice.
Fletcher PJ; Tampakeras M; Sinyard J; Slassi A; Isaac M; Higgins GA
Neuropharmacology; 2009 Sep; 57(3):259-67. PubMed ID: 19501602
[TBL] [Abstract][Full Text] [Related]
6. Anxiolytic activity of a novel potent serotonin 5-HT2C receptor antagonist FR260010: a comparison with diazepam and buspirone.
Harada K; Aota M; Inoue T; Matsuda R; Mihara T; Yamaji T; Ishibashi K; Matsuoka N
Eur J Pharmacol; 2006 Dec; 553(1-3):171-84. PubMed ID: 17074317
[TBL] [Abstract][Full Text] [Related]
7. Homology modeling and docking evaluation of aminergic G protein-coupled receptors.
McRobb FM; Capuano B; Crosby IT; Chalmers DK; Yuriev E
J Chem Inf Model; 2010 Apr; 50(4):626-37. PubMed ID: 20187660
[TBL] [Abstract][Full Text] [Related]
8. Contribution of a helix 5 locus to selectivity of hallucinogenic and nonhallucinogenic ligands for the human 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptors: direct and indirect effects on ligand affinity mediated by the same locus.
Almaula N; Ebersole BJ; Ballesteros JA; Weinstein H; Sealfon SC
Mol Pharmacol; 1996 Jul; 50(1):34-42. PubMed ID: 8700116
[TBL] [Abstract][Full Text] [Related]
9. Novel actions of inverse agonists on 5-HT2C receptor systems.
Berg KA; Stout BD; Cropper JD; Maayani S; Clarke WP
Mol Pharmacol; 1999 May; 55(5):863-72. PubMed ID: 10220565
[TBL] [Abstract][Full Text] [Related]
10. Homology model-based virtual screening for GPCR ligands using docking and target-biased scoring.
Radestock S; Weil T; Renner S
J Chem Inf Model; 2008 May; 48(5):1104-17. PubMed ID: 18442221
[TBL] [Abstract][Full Text] [Related]
11. Identification of structural determinants of ligand selectivity in 5-HT₂ receptor subtypes on the basis of protein-ligand interactions.
Jang JW; Kim MS; Cho YS; Cho AE; Pae AN
J Mol Graph Model; 2012 Sep; 38():342-53. PubMed ID: 23085173
[TBL] [Abstract][Full Text] [Related]
12. Reciprocal binding properties of 5-hydroxytryptamine type 2C receptor agonists and inverse agonists.
Westphal RS; Sanders-Bush E
Mol Pharmacol; 1994 Nov; 46(5):937-42. PubMed ID: 7969083
[TBL] [Abstract][Full Text] [Related]
13. Cocaine acts on accumbens monoamines and locomotor behavior via a 5-HT2A/2C receptor mechanism as shown by ketanserin: 24-h follow-up studies.
Broderick PA; Olabisi OA; Rahni DN; Zhou Y
Prog Neuropsychopharmacol Biol Psychiatry; 2004 May; 28(3):547-57. PubMed ID: 15093963
[TBL] [Abstract][Full Text] [Related]
14. Position 5.46 of the serotonin 5-HT2A receptor contributes to a species-dependent variation for the 5-HT2C agonist (R)-9-ethyl-1,3,4,10b-tetrahydro-7-trifluoromethylpyrazino[2,1-a]isoindol-6(2H)-one: impact on selectivity and toxicological evaluation.
Miller KJ; Wu GY; Varnes JG; Levesque P; Li J; Li D; Robl JA; Rossi KA; Wacker DA
Mol Pharmacol; 2009 Dec; 76(6):1211-9. PubMed ID: 19767451
[TBL] [Abstract][Full Text] [Related]
15. Inverse agonist and neutral antagonist actions of antidepressants at recombinant and native 5-hydroxytryptamine2C receptors: differential modulation of cell surface expression and signal transduction.
Chanrion B; Mannoury la Cour C; Gavarini S; Seimandi M; Vincent L; Pujol JF; Bockaert J; Marin P; Millan MJ
Mol Pharmacol; 2008 Mar; 73(3):748-57. PubMed ID: 18083778
[TBL] [Abstract][Full Text] [Related]
16. 5-HT(2C) receptor activation is a common mechanism on proerectile effects of apomorphine, oxytocin and melanotan-II in rats.
Kimura Y; Naitou Y; Wanibuchi F; Yamaguchi T
Eur J Pharmacol; 2008 Jul; 589(1-3):157-62. PubMed ID: 18582863
[TBL] [Abstract][Full Text] [Related]
17. 5-HT2C receptor modulators: a patent survey.
Lee J; Jung ME; Lee J
Expert Opin Ther Pat; 2010 Nov; 20(11):1429-55. PubMed ID: 20849206
[TBL] [Abstract][Full Text] [Related]
18. Region-dependent regulation of mesoaccumbens dopamine neurons in vivo by the constitutive activity of central serotonin2C receptors.
Navailles S; Moison D; Ryczko D; Spampinato U
J Neurochem; 2006 Nov; 99(4):1311-9. PubMed ID: 17018023
[TBL] [Abstract][Full Text] [Related]
19. A conservative, single-amino acid substitution in the second cytoplasmic domain of the human Serotonin2C receptor alters both ligand-dependent and -independent receptor signaling.
Berg KA; Dunlop J; Sanchez T; Silva M; Clarke WP
J Pharmacol Exp Ther; 2008 Mar; 324(3):1084-92. PubMed ID: 18065501
[TBL] [Abstract][Full Text] [Related]
20. Identification of putative agouti-related protein(87-132)-melanocortin-4 receptor interactions by homology molecular modeling and validation using chimeric peptide ligands.
Wilczynski A; Wang XS; Joseph CG; Xiang Z; Bauzo RM; Scott JW; Sorensen NB; Shaw AM; Millard WJ; Richards NG; Haskell-Luevano C
J Med Chem; 2004 Apr; 47(9):2194-207. PubMed ID: 15084118
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]