BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

415 related articles for article (PubMed ID: 20880848)

  • 1. Activation of AMP-activated protein kinase by temozolomide contributes to apoptosis in glioblastoma cells via p53 activation and mTORC1 inhibition.
    Zhang WB; Wang Z; Shu F; Jin YH; Liu HY; Wang QJ; Yang Y
    J Biol Chem; 2010 Dec; 285(52):40461-71. PubMed ID: 20880848
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine.
    Roos WP; Batista LF; Naumann SC; Wick W; Weller M; Menck CF; Kaina B
    Oncogene; 2007 Jan; 26(2):186-97. PubMed ID: 16819506
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of AMP-activated protein kinase is involved in vincristine-induced cell apoptosis in B16 melanoma cell.
    Chen MB; Shen WX; Yang Y; Wu XY; Gu JH; Lu PH
    J Cell Physiol; 2011 Jul; 226(7):1915-25. PubMed ID: 21506122
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Resveratrol enhances the antitumor effects of temozolomide in glioblastoma via ROS-dependent AMPK-TSC-mTOR signaling pathway.
    Yuan Y; Xue X; Guo RB; Sun XL; Hu G
    CNS Neurosci Ther; 2012 Jul; 18(7):536-46. PubMed ID: 22530672
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Capsaicin induces apoptosis in human osteosarcoma cells through AMPK-dependent and AMPK-independent signaling pathways.
    Ying H; Wang Z; Zhang Y; Yang TY; Ding ZH; Liu SY; Shao J; Liu Y; Fan XB
    Mol Cell Biochem; 2013 Dec; 384(1-2):229-37. PubMed ID: 24005536
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dual mTORC1/2 blockade inhibits glioblastoma brain tumor initiating cells in vitro and in vivo and synergizes with temozolomide to increase orthotopic xenograft survival.
    Luchman HA; Stechishin OD; Nguyen SA; Lun XQ; Cairncross JG; Weiss S
    Clin Cancer Res; 2014 Nov; 20(22):5756-67. PubMed ID: 25316808
    [TBL] [Abstract][Full Text] [Related]  

  • 7. O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells.
    Hermisson M; Klumpp A; Wick W; Wischhusen J; Nagel G; Roos W; Kaina B; Weller M
    J Neurochem; 2006 Feb; 96(3):766-76. PubMed ID: 16405512
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hispidulin enhances the anti-tumor effects of temozolomide in glioblastoma by activating AMPK.
    Wang Y; Liu W; He X; Fei Z
    Cell Biochem Biophys; 2015 Mar; 71(2):701-6. PubMed ID: 25315637
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O
    Chang KY; Hsu TI; Hsu CC; Tsai SY; Liu JJ; Chou SW; Liu MS; Liou JP; Ko CY; Chen KY; Hung JJ; Chang WC; Chuang CK; Kao TJ; Chuang JY
    Redox Biol; 2017 Oct; 13():655-664. PubMed ID: 28822335
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MGMT repletion after treatment of glioblastoma cells with temozolomide and O6-benzylguanine implicates NFκB and mutant p53.
    Vlachostergios PJ; Hatzidaki E; Papandreou CN
    Neurol Res; 2013 Oct; 35(8):879-82. PubMed ID: 23561593
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sulforaphane enhances temozolomide-induced apoptosis because of down-regulation of miR-21 via Wnt/β-catenin signaling in glioblastoma.
    Lan F; Pan Q; Yu H; Yue X
    J Neurochem; 2015 Sep; 134(5):811-8. PubMed ID: 25991372
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53.
    Naumann SC; Roos WP; Jöst E; Belohlavek C; Lennerz V; Schmidt CW; Christmann M; Kaina B
    Br J Cancer; 2009 Jan; 100(2):322-33. PubMed ID: 19127257
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Contribution of ATM and ATR to the resistance of glioblastoma and malignant melanoma cells to the methylating anticancer drug temozolomide.
    Eich M; Roos WP; Nikolova T; Kaina B
    Mol Cancer Ther; 2013 Nov; 12(11):2529-40. PubMed ID: 23960094
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Enhanced cytotoxic effect of radiation and temozolomide in malignant glioma cells: targeting PI3K-AKT-mTOR signaling, HSP90 and histone deacetylases.
    Choi EJ; Cho BJ; Lee DJ; Hwang YH; Chun SH; Kim HH; Kim IA
    BMC Cancer; 2014 Jan; 14():17. PubMed ID: 24418474
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oxidative cytotoxic agent withaferin A resensitizes temozolomide-resistant glioblastomas via MGMT depletion and induces apoptosis through Akt/mTOR pathway inhibitory modulation.
    Grogan PT; Sarkaria JN; Timmermann BN; Cohen MS
    Invest New Drugs; 2014 Aug; 32(4):604-17. PubMed ID: 24718901
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Temozolomide Resistance in Glioblastoma Cell Lines: Implication of MGMT, MMR, P-Glycoprotein and CD133 Expression.
    Perazzoli G; Prados J; Ortiz R; Caba O; Cabeza L; Berdasco M; Gónzalez B; Melguizo C
    PLoS One; 2015; 10(10):e0140131. PubMed ID: 26447477
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biochemical changes associated with a multidrug-resistant phenotype of a human glioma cell line with temozolomide-acquired resistance.
    Ma J; Murphy M; O'Dwyer PJ; Berman E; Reed K; Gallo JM
    Biochem Pharmacol; 2002 Apr; 63(7):1219-28. PubMed ID: 11960598
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Temozolomide-mediated DNA methylation in human myeloid precursor cells: differential involvement of intrinsic and extrinsic apoptotic pathways.
    Wang H; Cai S; Ernstberger A; Bailey BJ; Wang MZ; Cai W; Goebel WS; Czader MB; Crean C; Suvannasankha A; Shokolenkoc I; Wilson GL; Baluyut AR; Mayo LD; Pollok KE
    Clin Cancer Res; 2013 May; 19(10):2699-709. PubMed ID: 23536437
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity.
    Shi L; Chen J; Yang J; Pan T; Zhang S; Wang Z
    Brain Res; 2010 Sep; 1352():255-64. PubMed ID: 20633539
    [TBL] [Abstract][Full Text] [Related]  

  • 20. p53 upregulated modulator of apoptosis sensitizes drug-resistant U251 glioblastoma stem cells to temozolomide through enhanced apoptosis.
    Miao W; Liu X; Wang H; Fan Y; Lian S; Yang X; Wang X; Guo G; Li Q; Wang S
    Mol Med Rep; 2015 Jun; 11(6):4165-73. PubMed ID: 25625235
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.