These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

199 related articles for article (PubMed ID: 20888084)

  • 1. Characteristics of known drug space. Natural products, their derivatives and synthetic drugs.
    Bade R; Chan HF; Reynisson J
    Eur J Med Chem; 2010 Dec; 45(12):5646-52. PubMed ID: 20888084
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A review of the natural occurrence, synthetic production and use of carcinogenic hydrazines and related chemicals.
    Toth B
    In Vivo; 2000; 14(2):299-319. PubMed ID: 10836203
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Lessons from natural molecules.
    Clardy J; Walsh C
    Nature; 2004 Dec; 432(7019):829-37. PubMed ID: 15602548
    [TBL] [Abstract][Full Text] [Related]  

  • 4. [Strategy of molecular design of drugs: the unification of macro-properties and micro-structures of a molecule].
    Guo ZR
    Yao Xue Xue Bao; 2008 Mar; 43(3):227-33. PubMed ID: 18630256
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Natural product hybrids as new leads for drug discovery.
    Tietze LF; Bell HP; Chandrasekhar S
    Angew Chem Int Ed Engl; 2003 Sep; 42(34):3996-4028. PubMed ID: 12973759
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Size estimation of chemical space: how big is it?
    Drew KL; Baiman H; Khwaounjoo P; Yu B; Reynisson J
    J Pharm Pharmacol; 2012 Apr; 64(4):490-5. PubMed ID: 22420655
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The evolution of synthetic oral drug properties.
    Proudfoot JR
    Bioorg Med Chem Lett; 2005 Feb; 15(4):1087-90. PubMed ID: 15686918
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Known drug space as a metric in exploring the boundaries of drug-like chemical space.
    Mirza A; Desai R; Reynisson J
    Eur J Med Chem; 2009 Dec; 44(12):5006-11. PubMed ID: 19782440
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthetic approaches towards structurally diverse gamma-butyrolactone natural-product-like compounds.
    Seitz M; Reiser O
    Curr Opin Chem Biol; 2005 Jun; 9(3):285-92. PubMed ID: 15939330
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular dynamics study of the encapsulation capability of a PCL-PEO based block copolymer for hydrophobic drugs with different spatial distributions of hydrogen bond donors and acceptors.
    Patel SK; Lavasanifar A; Choi P
    Biomaterials; 2010 Mar; 31(7):1780-6. PubMed ID: 19962756
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Development of specific "drug-like property" rules for carboxylate-containing oral drug candidates.
    Böcker A; Bonneau PR; Hucke O; Jakalian A; Edwards PJ
    ChemMedChem; 2010 Dec; 5(12):2102-13. PubMed ID: 20979082
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Drugs in other drugs: a new look at drugs as fragments.
    Siegel MG; Vieth M
    Drug Discov Today; 2007 Jan; 12(1-2):71-9. PubMed ID: 17198975
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Advancing chemistry and biology through diversity-oriented synthesis of natural product-like libraries.
    Shang S; Tan DS
    Curr Opin Chem Biol; 2005 Jun; 9(3):248-58. PubMed ID: 15939326
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Small molecule natural products in the discovery of therapeutic agents: the synthesis connection.
    Wilson RM; Danishefsky SJ
    J Org Chem; 2006 Oct; 71(22):8329-51. PubMed ID: 17064003
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A comparison of the chemical properties of drugs and FEMA/FDA notified GRAS chemical compounds used in the food industry.
    Sprous DG; Salemme FR
    Food Chem Toxicol; 2007 Aug; 45(8):1419-27. PubMed ID: 17368904
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Making carbon-nitrogen bonds in biological and chemical synthesis.
    Hili R; Yudin AK
    Nat Chem Biol; 2006 Jun; 2(6):284-7. PubMed ID: 16710330
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Developing a drug-like natural product library.
    Quinn RJ; Carroll AR; Pham NB; Baron P; Palframan ME; Suraweera L; Pierens GK; Muresan S
    J Nat Prod; 2008 Mar; 71(3):464-8. PubMed ID: 18257534
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Property distributions: differences between drugs, natural products, and molecules from combinatorial chemistry.
    Feher M; Schmidt JM
    J Chem Inf Comput Sci; 2003; 43(1):218-27. PubMed ID: 12546556
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Defining Known Drug Space Using DFT.
    Matuszek AM; Reynisson J
    Mol Inform; 2016 Feb; 35(2):46-53. PubMed ID: 27491789
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biological activity predictions, crystallographic comparison and hydrogen bonding analysis of cholane derivatives.
    Rajnikant ; Dinesh ; Chand B
    Indian J Biochem Biophys; 2007 Dec; 44(6):458-69. PubMed ID: 18320845
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.