275 related articles for article (PubMed ID: 20888243)
1. Design of more potent squalene synthase inhibitors with multiple activities.
Kourounakis AP; Matralis AN; Nikitakis A
Bioorg Med Chem; 2010 Nov; 18(21):7402-12. PubMed ID: 20888243
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis and pharmacobiological evaluation of novel acrylic acid derivatives acting as lipoxygenase and cyclooxygenase-1 inhibitors with antioxidant and anti-inflammatory activities.
Pontiki E; Hadjipavlou-Litina D; Litinas K; Nicolotti O; Carotti A
Eur J Med Chem; 2011 Jan; 46(1):191-200. PubMed ID: 21106277
[TBL] [Abstract][Full Text] [Related]
3. Developing potential agents against atherosclerosis: Design, synthesis and pharmacological evaluation of novel dual inhibitors of oxidative stress and Squalene Synthase activity.
Katselou MG; Matralis AN; Kourounakis AP
Eur J Med Chem; 2017 Sep; 138():748-760. PubMed ID: 28728107
[TBL] [Abstract][Full Text] [Related]
4. Design of novel potent antihyperlipidemic agents with antioxidant/anti-inflammatory properties: exploiting phenothiazine's strong antioxidant activity.
Matralis AN; Kourounakis AP
J Med Chem; 2014 Mar; 57(6):2568-81. PubMed ID: 24568631
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and evaluation of the antioxidant and anti-inflammatory activity of novel coumarin-3-aminoamides and their alpha-lipoic acid adducts.
Melagraki G; Afantitis A; Igglessi-Markopoulou O; Detsi A; Koufaki M; Kontogiorgis C; Hadjipavlou-Litina DJ
Eur J Med Chem; 2009 Jul; 44(7):3020-6. PubMed ID: 19232783
[TBL] [Abstract][Full Text] [Related]
6. Antihyperlipidemic morpholine derivatives with antioxidant activity: An investigation of the aromatic substitution.
Ladopoulou EM; Matralis AN; Nikitakis A; Kourounakis AP
Bioorg Med Chem; 2015 Nov; 23(21):7015-23. PubMed ID: 26433631
[TBL] [Abstract][Full Text] [Related]
7. Lipid-lowering (hetero)aromatic tetrahydro-1,4-oxazine derivatives with antioxidant and squalene synthase inhibitory activity.
Kourounakis AP; Charitos C; Rekka EA; Kourounakis PN
J Med Chem; 2008 Sep; 51(18):5861-5. PubMed ID: 18754614
[TBL] [Abstract][Full Text] [Related]
8. Design of Multifaceted Antioxidants: Shifting towards Anti-Inflammatory and Antihyperlipidemic Activity.
Tzara A; Lambrinidis G; Kourounakis A
Molecules; 2021 Aug; 26(16):. PubMed ID: 34443516
[TBL] [Abstract][Full Text] [Related]
9. Discovery of novel tricyclic compounds as squalene synthase inhibitors.
Ichikawa M; Ohtsuka M; Ohki H; Haginoya N; Itoh M; Sugita K; Usui H; Suzuki M; Terayama K; Kanda A
Bioorg Med Chem; 2012 May; 20(9):3072-93. PubMed ID: 22464687
[TBL] [Abstract][Full Text] [Related]
10. Novel benzoxazine and benzothiazine derivatives as multifunctional antihyperlipidemic agents.
Matralis AN; Katselou MG; Nikitakis A; Kourounakis AP
J Med Chem; 2011 Aug; 54(15):5583-91. PubMed ID: 21702499
[TBL] [Abstract][Full Text] [Related]
11. Fragment-based design, docking, synthesis, biological evaluation and structure-activity relationships of 2-benzo/benzisothiazolimino-5-aryliden-4-thiazolidinones as cycloxygenase/lipoxygenase inhibitors.
Eleftheriou P; Geronikaki A; Hadjipavlou-Litina D; Vicini P; Filz O; Filimonov D; Poroikov V; Chaudhaery SS; Roy KK; Saxena AK
Eur J Med Chem; 2012 Jan; 47(1):111-24. PubMed ID: 22119153
[TBL] [Abstract][Full Text] [Related]
12. Discovery of atrop fixed alkoxy-aminobenzhydrol derivatives: novel, highly potent and orally efficacious squalene synthase inhibitors.
Ichikawa M; Yokomizo A; Itoh M; Haginoya N; Sugita K; Usui H; Terayama K; Kanda A
Bioorg Med Chem; 2011 Sep; 19(17):5207-24. PubMed ID: 21802309
[TBL] [Abstract][Full Text] [Related]
13. Identification of 4H,6H-[2]benzoxepino[4,5-c][1,2]oxazoles as novel squalene synthase inhibitors.
Griebenow N; Buchmueller A; Kolkhof P; Schamberger J; Bischoff H
Bioorg Med Chem Lett; 2011 Jun; 21(12):3648-53. PubMed ID: 21576018
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and activity of a novel series of 3-biarylquinuclidine squalene synthase inhibitors.
Brown GR; Clarke DS; Foubister AJ; Freeman S; Harrison PJ; Johnson MC; Mallion KB; McCormick J; McTaggart F; Reid AC; Smith GJ; Taylor MJ
J Med Chem; 1996 Jul; 39(15):2971-9. PubMed ID: 8709131
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and biological evaluation of new quinoxaline derivatives as antioxidant and anti-inflammatory agents.
Burguete A; Pontiki E; Hadjipavlou-Litina D; Ancizu S; Villar R; Solano B; Moreno E; Torres E; Pérez S; Aldana I; Monge A
Chem Biol Drug Des; 2011 Apr; 77(4):255-67. PubMed ID: 21244639
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and pharmacochemical evaluation of novel aryl-acetic acid inhibitors of lipoxygenase, antioxidants, and anti-inflammatory agents.
Pontiki E; Hadjipavlou-Litina D
Bioorg Med Chem; 2007 Sep; 15(17):5819-27. PubMed ID: 17604175
[TBL] [Abstract][Full Text] [Related]
17. New multifunctional Di-tert-butylphenoloctahydro(pyrido/benz)oxazine derivatives with antioxidant, antihyperlipidemic, and antidiabetic action.
Ladopoulou E; Matralis AN; Kourounakis AP
J Med Chem; 2013 Apr; 56(8):3330-8. PubMed ID: 23581491
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and biological evaluation of novel propylamine derivatives as orally active squalene synthase inhibitors.
Ishihara T; Kakuta H; Moritani H; Ugawa T; Yanagisawa I
Bioorg Med Chem; 2004 Nov; 12(22):5899-908. PubMed ID: 15498666
[TBL] [Abstract][Full Text] [Related]
19. The novel ketoprofen amides--synthesis and biological evaluation as antioxidants, lipoxygenase inhibitors and cytostatic agents.
Rajić Z; Hadjipavlou-Litina D; Pontiki E; Kralj M; Suman L; Zorc B
Chem Biol Drug Des; 2010 Jun; 75(6):641-52. PubMed ID: 20337784
[TBL] [Abstract][Full Text] [Related]
20. Discovery of a new 2-aminobenzhydrol template for highly potent squalene synthase inhibitors.
Ichikawa M; Yokomizo A; Itoh M; Usui H; Shimizu H; Suzuki M; Terayama K; Kanda A; Sugita K
Bioorg Med Chem; 2011 Mar; 19(6):1930-49. PubMed ID: 21353782
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]