308 related articles for article (PubMed ID: 20924113)
1. eIF2{alpha} Kinase PKR modulates the hypoxic response by Stat3-dependent transcriptional suppression of HIF-1{alpha}.
Papadakis AI; Paraskeva E; Peidis P; Muaddi H; Li S; Raptis L; Pantopoulos K; Simos G; Koromilas AE
Cancer Res; 2010 Oct; 70(20):7820-9. PubMed ID: 20924113
[TBL] [Abstract][Full Text] [Related]
2. mTORC1 drives HIF-1α and VEGF-A signalling via multiple mechanisms involving 4E-BP1, S6K1 and STAT3.
Dodd KM; Yang J; Shen MH; Sampson JR; Tee AR
Oncogene; 2015 Apr; 34(17):2239-50. PubMed ID: 24931163
[TBL] [Abstract][Full Text] [Related]
3. Suppression of hypoxia-inducible factor 1α (HIF-1α) by tirapazamine is dependent on eIF2α phosphorylation rather than the mTORC1/4E-BP1 pathway.
Zhang J; Cao J; Weng Q; Wu R; Yan Y; Jing H; Zhu H; He Q; Yang B
PLoS One; 2010 Nov; 5(11):e13910. PubMed ID: 21085474
[TBL] [Abstract][Full Text] [Related]
4. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
Carroll VA; Ashcroft M
Cancer Res; 2006 Jun; 66(12):6264-70. PubMed ID: 16778202
[TBL] [Abstract][Full Text] [Related]
5. Magnolol suppresses hypoxia-induced angiogenesis via inhibition of HIF-1α/VEGF signaling pathway in human bladder cancer cells.
Chen MC; Lee CF; Huang WH; Chou TC
Biochem Pharmacol; 2013 May; 85(9):1278-87. PubMed ID: 23416116
[TBL] [Abstract][Full Text] [Related]
6. Signal transducer and activator of transcription 3 is required for hypoxia-inducible factor-1alpha RNA expression in both tumor cells and tumor-associated myeloid cells.
Niu G; Briggs J; Deng J; Ma Y; Lee H; Kortylewski M; Kujawski M; Kay H; Cress WD; Jove R; Yu H
Mol Cancer Res; 2008 Jul; 6(7):1099-105. PubMed ID: 18644974
[TBL] [Abstract][Full Text] [Related]
7. A perylene derivative regulates HIF-1α and Stat3 signaling pathways.
Chen H; Guan Y; Yuan G; Zhang Q; Jing N
Bioorg Med Chem; 2014 Feb; 22(4):1496-505. PubMed ID: 24485121
[TBL] [Abstract][Full Text] [Related]
8. STAT3 is a potential modulator of HIF-1-mediated VEGF expression in human renal carcinoma cells.
Jung JE; Lee HG; Cho IH; Chung DH; Yoon SH; Yang YM; Lee JW; Choi S; Park JW; Ye SK; Chung MH
FASEB J; 2005 Aug; 19(10):1296-8. PubMed ID: 15919761
[TBL] [Abstract][Full Text] [Related]
9. Opposite functions of HIF-α isoforms in VEGF induction by TGF-β1 under non-hypoxic conditions.
Chae KS; Kang MJ; Lee JH; Ryu BK; Lee MG; Her NG; Ha TK; Han J; Kim YK; Chi SG
Oncogene; 2011 Mar; 30(10):1213-28. PubMed ID: 21057546
[TBL] [Abstract][Full Text] [Related]
10. The double-stranded RNA-activated protein kinase PKR is dispensable for regulation of translation initiation in response to either calcium mobilization from the endoplasmic reticulum or essential amino acid starvation.
Kimball SR; Clemens MJ; Tilleray VJ; Wek RC; Horetsky RL; Jefferson LS
Biochem Biophys Res Commun; 2001 Jan; 280(1):293-300. PubMed ID: 11162513
[TBL] [Abstract][Full Text] [Related]
11. HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas.
Gray MJ; Zhang J; Ellis LM; Semenza GL; Evans DB; Watowich SS; Gallick GE
Oncogene; 2005 Apr; 24(19):3110-20. PubMed ID: 15735682
[TBL] [Abstract][Full Text] [Related]
12. HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression.
Laughner E; Taghavi P; Chiles K; Mahon PC; Semenza GL
Mol Cell Biol; 2001 Jun; 21(12):3995-4004. PubMed ID: 11359907
[TBL] [Abstract][Full Text] [Related]
13. In vivo evidence suggesting reciprocal renal hypoxia-inducible factor-1 upregulation and signal transducer and activator of transcription 3 activation in response to hypoxic and non-hypoxic stimuli.
Nechemia-Arbely Y; Khamaisi M; Rosenberger C; Koesters R; Shina A; Geva C; Shriki A; Klaus S; Rosen S; Rose-John S; Galun E; Axelrod JH; Heyman SN
Clin Exp Pharmacol Physiol; 2013 Apr; 40(4):262-72. PubMed ID: 23384058
[TBL] [Abstract][Full Text] [Related]
14. Tanshinone I inhibits tumor angiogenesis by reducing Stat3 phosphorylation at Tyr705 and hypoxia-induced HIF-1α accumulation in both endothelial and tumor cells.
Wang Y; Li JX; Wang YQ; Miao ZH
Oncotarget; 2015 Jun; 6(18):16031-42. PubMed ID: 26202747
[TBL] [Abstract][Full Text] [Related]
15. UVC inhibits HIF-1alpha protein translation by a DNA damage- and topoisomerase I-independent pathway.
Rapisarda A; Melillo G
Oncogene; 2007 Oct; 26(48):6875-84. PubMed ID: 17496931
[TBL] [Abstract][Full Text] [Related]
16. LB-1 Exerts Antitumor Activity in Pancreatic Cancer by Inhibiting HIF-1α and Stat3 Signaling.
Niu F; Li Y; Lai FF; Ni L; Ji M; Jin J; Yang HZ; Wang C; Zhang DM; Chen XG
J Cell Physiol; 2015 Sep; 230(9):2212-23. PubMed ID: 25655308
[TBL] [Abstract][Full Text] [Related]
17. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.
Blancher C; Moore JW; Robertson N; Harris AL
Cancer Res; 2001 Oct; 61(19):7349-55. PubMed ID: 11585776
[TBL] [Abstract][Full Text] [Related]
18. Regulation of S100A4 expression via the JAK2-STAT3 pathway in rhomboid-phenotype pulmonary arterial smooth muscle cells exposure to hypoxia.
Liu T; Li Y; Lin K; Yin H; He B; Zheng M; Wang G
Int J Biochem Cell Biol; 2012 Aug; 44(8):1337-45. PubMed ID: 22561747
[TBL] [Abstract][Full Text] [Related]
19. Renal cancer cells lacking hypoxia inducible factor (HIF)-1alpha expression maintain vascular endothelial growth factor expression through HIF-2alpha.
Shinojima T; Oya M; Takayanagi A; Mizuno R; Shimizu N; Murai M
Carcinogenesis; 2007 Mar; 28(3):529-36. PubMed ID: 16920734
[TBL] [Abstract][Full Text] [Related]
20. HIF-1α activation under glucose deprivation plays a central role in the acquisition of anti-apoptosis in human colon cancer cells.
Nishimoto A; Kugimiya N; Hosoyama T; Enoki T; Li TS; Hamano K
Int J Oncol; 2014 Jun; 44(6):2077-84. PubMed ID: 24718784
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]