BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 20925094)

  • 1. Design, synthesis, and molecular-modeling study of aminothienopyridine analogues of tacrine for Alzheimer's disease.
    Badran MM; Abdel Hakeem M; Abuel-Maaty SM; El-Malah A; Abdel Salam RM
    Arch Pharm (Weinheim); 2010 Oct; 343(10):590-601. PubMed ID: 20925094
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel tacrine analogs as potential cholinesterase inhibitors in Alzheimer's disease.
    El-Malah A; Gedawy EM; Kassab AE; Salam RM
    Arch Pharm (Weinheim); 2014 Feb; 347(2):96-103. PubMed ID: 24343873
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis, design and biological evaluation of novel highly potent tacrine congeners for the treatment of Alzheimer's disease.
    Hamulakova S; Janovec L; Hrabinova M; Kristian P; Kuca K; Banasova M; Imrich J
    Eur J Med Chem; 2012 Sep; 55():23-31. PubMed ID: 22818849
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design and synthesis of tacrine-ferulic acid hybrids as multi-potent anti-Alzheimer drug candidates.
    Fang L; Kraus B; Lehmann J; Heilmann J; Zhang Y; Decker M
    Bioorg Med Chem Lett; 2008 May; 18(9):2905-9. PubMed ID: 18406135
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and in vitro evaluation of N-alkyl-7-methoxytacrine hydrochlorides as potential cholinesterase inhibitors in Alzheimer disease.
    Korabecny J; Musilek K; Holas O; Binder J; Zemek F; Marek J; Pohanka M; Opletalova V; Dohnal V; Kuca K
    Bioorg Med Chem Lett; 2010 Oct; 20(20):6093-5. PubMed ID: 20817518
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and evaluation of heterobivalent tacrine derivatives as potential multi-functional anti-Alzheimer agents.
    Luo W; Li YP; He Y; Huang SL; Li D; Gu LQ; Huang ZS
    Eur J Med Chem; 2011 Jun; 46(6):2609-16. PubMed ID: 21497959
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and neuroprotective evaluation of novel tacrine-benzothiazole hybrids as multi-targeted compounds against Alzheimer's disease.
    Keri RS; Quintanova C; Marques SM; Esteves AR; Cardoso SM; Santos MA
    Bioorg Med Chem; 2013 Aug; 21(15):4559-69. PubMed ID: 23768661
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological evaluation of NO-donor-tacrine hybrids as hepatoprotective anti-Alzheimer drug candidates.
    Fang L; Appenroth D; Decker M; Kiehntopf M; Roegler C; Deufel T; Fleck C; Peng S; Zhang Y; Lehmann J
    J Med Chem; 2008 Feb; 51(4):713-6. PubMed ID: 18232655
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis and evaluation of novel tacrine-coumarin hybrids as multifunctional cholinesterase inhibitors against Alzheimer's disease.
    Xie SS; Wang XB; Li JY; Yang L; Kong LY
    Eur J Med Chem; 2013 Jun; 64():540-53. PubMed ID: 23685572
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pyrano[3,2-c]quinoline-6-chlorotacrine hybrids as a novel family of acetylcholinesterase- and beta-amyloid-directed anti-Alzheimer compounds.
    Camps P; Formosa X; Galdeano C; Muñoz-Torrero D; Ramírez L; Gómez E; Isambert N; Lavilla R; Badia A; Clos MV; Bartolini M; Mancini F; Andrisano V; Arce MP; Rodríguez-Franco MI; Huertas O; Dafni T; Luque FJ
    J Med Chem; 2009 Sep; 52(17):5365-79. PubMed ID: 19663388
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis, in vitro pharmacology, and molecular modeling of very potent tacrine-huperzine A hybrids as acetylcholinesterase inhibitors of potential interest for the treatment of Alzheimer's disease.
    Camps P; El Achab R; Görbig DM; Morral J; Muñoz-Torrero D; Badia A; Eladi Baños J; Vivas NM; Barril X; Orozco M; Luque FJ
    J Med Chem; 1999 Aug; 42(17):3227-42. PubMed ID: 10464010
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and evaluation of tacrine-E2020 hybrids as acetylcholinesterase inhibitors for the treatment of Alzheimer's disease.
    Shao D; Zou C; Luo C; Tang X; Li Y
    Bioorg Med Chem Lett; 2004 Sep; 14(18):4639-42. PubMed ID: 15324879
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tacrine-flurbiprofen hybrids as multifunctional drug candidates for the treatment of Alzheimer's disease.
    Chen Y; Sun J; Peng S; Liao H; Zhang Y; Lehmann J
    Arch Pharm (Weinheim); 2013 Dec; 346(12):865-71. PubMed ID: 24203864
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological assessment of diversely substituted furo[2,3-b]quinolin-4-amine and pyrrolo[2,3-b]quinolin-4-amine derivatives, as novel tacrine analogues.
    Martins C; Carreiras MC; León R; de los Ríos C; Bartolini M; Andrisano V; Iriepa I; Moraleda I; Gálvez E; García M; Egea J; Samadi A; Chioua M; Marco-Contelles J
    Eur J Med Chem; 2011 Dec; 46(12):6119-30. PubMed ID: 22000936
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and pharmacological evaluation of multifunctional tacrine derivatives against several disease pathways of AD.
    Digiacomo M; Chen Z; Wang S; Lapucci A; Macchia M; Yang X; Chu J; Han Y; Pi R; Rapposelli S
    Bioorg Med Chem Lett; 2015 Feb; 25(4):807-10. PubMed ID: 25597007
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis, and biological evaluation of dual binding site acetylcholinesterase inhibitors: new disease-modifying agents for Alzheimer's disease.
    Muñoz-Ruiz P; Rubio L; García-Palomero E; Dorronsoro I; del Monte-Millán M; Valenzuela R; Usán P; de Austria C; Bartolini M; Andrisano V; Bidon-Chanal A; Orozco M; Luque FJ; Medina M; Martínez A
    J Med Chem; 2005 Nov; 48(23):7223-33. PubMed ID: 16279781
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis, biological properties, and molecular modeling investigations of novel tacrine derivatives with a combination of acetylcholinesterase inhibition and cannabinoid CB1 receptor antagonism.
    Lange JH; Coolen HK; van der Neut MA; Borst AJ; Stork B; Verveer PC; Kruse CG
    J Med Chem; 2010 Feb; 53(3):1338-46. PubMed ID: 20047331
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis and evaluation of novel tacrine-rhein hybrids as multifunctional agents for the treatment of Alzheimer's disease.
    Li SY; Jiang N; Xie SS; Wang KD; Wang XB; Kong LY
    Org Biomol Chem; 2014 Feb; 12(5):801-14. PubMed ID: 24310227
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis and biological evaluation of new 2-benzoxazolinone derivatives as potential cholinesterase inhibitors for therapy of alzheimer's disease.
    Szymański P; Janik A; Zurek E; Mikiciuk-Olasik E
    Pharmazie; 2011 Jun; 66(6):399-403. PubMed ID: 21699076
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Combined 3D-QSAR, molecular docking, and molecular dynamics study of tacrine derivatives as potential acetylcholinesterase (AChE) inhibitors of Alzheimer's disease.
    Zhou A; Hu J; Wang L; Zhong G; Pan J; Wu Z; Hui A
    J Mol Model; 2015 Oct; 21(10):277. PubMed ID: 26438408
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.