BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 20926620)

  • 1. Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
    Koga T; Fujiwara R; Nakajima M; Yokoi T
    Drug Metab Dispos; 2011 Jan; 39(1):54-60. PubMed ID: 20926620
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Carboxylic acid drug-induced DNA nicking in HEK293 cells expressing human UDP-glucuronosyltransferases: role of acyl glucuronide metabolites and glycation pathways.
    Southwood HT; DeGraaf YC; Mackenzie PI; Miners JO; Burcham PC; Sallustio BC
    Chem Res Toxicol; 2007 Oct; 20(10):1520-7. PubMed ID: 17880178
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bioactivation of carboxylic acid compounds by UDP-Glucuronosyltransferases to DNA-damaging intermediates: role of glycoxidation and oxidative stress in genotoxicity.
    Sallustio BC; Degraaf YC; Weekley JS; Burcham PC
    Chem Res Toxicol; 2006 May; 19(5):683-91. PubMed ID: 16696571
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Glucuronidation of amines and other xenobiotics catalyzed by expressed human UDP-glucuronosyltransferase 1A3.
    Green MD; King CD; Mojarrabi B; Mackenzie PI; Tephly TR
    Drug Metab Dispos; 1998 Jun; 26(6):507-12. PubMed ID: 9616184
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Application of quantitative structure-toxicity relationships for acute NSAID cytotoxicity in rat hepatocytes.
    Siraki AG; Chevaldina T; O'Brien PJ
    Chem Biol Interact; 2005 Feb; 151(3):177-91. PubMed ID: 15733539
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Contribution of cytochrome P450 and UDT-glucuronosyltransferase to the metabolism of drugs containing carboxylic acid groups: risk assessment of acylglucuronides using human hepatocytes.
    Jinno N; Tagashira M; Tsurui K; Yamada S
    Xenobiotica; 2014 Aug; 44(8):677-86. PubMed ID: 24575896
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In vitro inhibitory effects of non-steroidal anti-inflammatory drugs on 4-methylumbelliferone glucuronidation in recombinant human UDP-glucuronosyltransferase 1A9--potent inhibition by niflumic acid.
    Mano Y; Usui T; Kamimura H
    Biopharm Drug Dispos; 2006 Jan; 27(1):1-6. PubMed ID: 16278927
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Stereoselective Covalent Adduct Formation of Acyl Glucuronide Metabolite of Nonsteroidal Anti-Inflammatory Drugs with UDP-Glucuronosyltransferase.
    Kawase A; Yamashita R; Yoshizato T; Yoshikawa M; Shimada H; Iwaki M
    Int J Mol Sci; 2022 Apr; 23(9):. PubMed ID: 35563116
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanistic studies on the bioactivation of diclofenac: identification of diclofenac-S-acyl-glutathione in vitro in incubations with rat and human hepatocytes.
    Grillo MP; Hua F; Knutson CG; Ware JA; Li C
    Chem Res Toxicol; 2003 Nov; 16(11):1410-7. PubMed ID: 14615966
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Glucuronidation of carboxylic acid containing compounds by UDP-glucuronosyltransferase isoforms.
    Sakaguchi K; Green M; Stock N; Reger TS; Zunic J; King C
    Arch Biochem Biophys; 2004 Apr; 424(2):219-25. PubMed ID: 15047194
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Glucuronidation of fenamates: kinetic studies using human kidney cortical microsomes and recombinant UDP-glucuronosyltransferase (UGT) 1A9 and 2B7.
    Gaganis P; Miners JO; Knights KM
    Biochem Pharmacol; 2007 May; 73(10):1683-91. PubMed ID: 17343829
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Glucuronidation of 1'-hydroxyestragole (1'-HE) by human UDP-glucuronosyltransferases UGT2B7 and UGT1A9.
    Iyer LV; Ho MN; Shinn WM; Bradford WW; Tanga MJ; Nath SS; Green CE
    Toxicol Sci; 2003 May; 73(1):36-43. PubMed ID: 12657745
    [TBL] [Abstract][Full Text] [Related]  

  • 13. UDP-glucuronosyltransferase-dependent bioactivation of clofibric acid to a DNA-damaging intermediate in mouse hepatocytes.
    Ghaoui R; Sallustio BC; Burcham PC; Fontaine FR
    Chem Biol Interact; 2003 May; 145(2):201-11. PubMed ID: 12686496
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Product inhibition of UDP-glucuronosyltransferase (UGT) enzymes by UDP obfuscates the inhibitory effects of UGT substrates.
    Fujiwara R; Nakajima M; Yamanaka H; Katoh M; Yokoi T
    Drug Metab Dispos; 2008 Feb; 36(2):361-7. PubMed ID: 17998297
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Epirubicin glucuronidation is catalyzed by human UDP-glucuronosyltransferase 2B7.
    Innocenti F; Iyer L; Ramírez J; Green MD; Ratain MJ
    Drug Metab Dispos; 2001 May; 29(5):686-92. PubMed ID: 11302935
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human UDP-glucuronosyltransferase (UGT)1A3 enzyme conjugates chenodeoxycholic acid in the liver.
    Trottier J; Verreault M; Grepper S; Monté D; Bélanger J; Kaeding J; Caron P; Inaba TT; Barbier O
    Hepatology; 2006 Nov; 44(5):1158-70. PubMed ID: 17058234
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Non-steroidal anti-inflammatory drugs interact with testosterone glucuronidation.
    Sten T; Finel M; Ask B; Rane A; Ekström L
    Steroids; 2009 Nov; 74(12):971-7. PubMed ID: 19643121
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia).
    Ghosal A; Hapangama N; Yuan Y; Achanfuo-Yeboah J; Iannucci R; Chowdhury S; Alton K; Patrick JE; Zbaida S
    Drug Metab Dispos; 2004 Mar; 32(3):314-20. PubMed ID: 14977865
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In vitro glucuronidation of thyroxine and triiodothyronine by liver microsomes and recombinant human UDP-glucuronosyltransferases.
    Tong Z; Li H; Goljer I; McConnell O; Chandrasekaran A
    Drug Metab Dispos; 2007 Dec; 35(12):2203-10. PubMed ID: 17875670
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Comparison of inhibition potentials of drugs against zidovudine glucuronidation in rat hepatocytes and liver microsomes.
    Mano Y; Usui T; Kamimura H
    Drug Metab Dispos; 2007 Apr; 35(4):602-6. PubMed ID: 17267620
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.