279 related articles for article (PubMed ID: 20931094)
1. Novel characteristics of a trafficking-defective G572R-hERG channel linked to hereditary long QT syndrome.
Lian J; Huang N; Zhou J; Ge S; Huang X; Huo J; Liu L; Xu W; Zhang S; Yang X; Zhou J; Huang C
Can J Cardiol; 2010 Oct; 26(8):417-22. PubMed ID: 20931094
[TBL] [Abstract][Full Text] [Related]
2. Most LQT2 mutations reduce Kv11.1 (hERG) current by a class 2 (trafficking-deficient) mechanism.
Anderson CL; Delisle BP; Anson BD; Kilby JA; Will ML; Tester DJ; Gong Q; Zhou Z; Ackerman MJ; January CT
Circulation; 2006 Jan; 113(3):365-73. PubMed ID: 16432067
[TBL] [Abstract][Full Text] [Related]
3. HERG-F463L potassium channels linked to long QT syndrome reduce I(Kr) current by a trafficking-deficient mechanism.
Yang HT; Sun CF; Cui CC; Xue XL; Zhang AF; Li HB; Wang DQ; Shu J
Clin Exp Pharmacol Physiol; 2009 Aug; 36(8):822-7. PubMed ID: 19215240
[TBL] [Abstract][Full Text] [Related]
4. Properties of WT and mutant hERG K(+) channels expressed in neonatal mouse cardiomyocytes.
Lin EC; Holzem KM; Anson BD; Moungey BM; Balijepalli SY; Tester DJ; Ackerman MJ; Delisle BP; Balijepalli RC; January CT
Am J Physiol Heart Circ Physiol; 2010 Jun; 298(6):H1842-9. PubMed ID: 20363883
[TBL] [Abstract][Full Text] [Related]
5. The G604S-hERG mutation alters the biophysical properties and exerts a dominant-negative effect on expression of hERG channels in HEK293 cells.
Huo J; Zhang Y; Huang N; Liu P; Huang C; Guo X; Jiang W; Zhou N; Grace A; Huang CL; Ma A
Pflugers Arch; 2008 Aug; 456(5):917-28. PubMed ID: 18386051
[TBL] [Abstract][Full Text] [Related]
6. Partially dominant mutant channel defect corresponding with intermediate LQT2 phenotype.
Krishnan Y; Zheng R; Walsh C; Tang Y; McDonald TV
Pacing Clin Electrophysiol; 2012 Jan; 35(1):3-16. PubMed ID: 21951015
[TBL] [Abstract][Full Text] [Related]
7. Novel mechanism associated with an inherited cardiac arrhythmia: defective protein trafficking by the mutant HERG (G601S) potassium channel.
Furutani M; Trudeau MC; Hagiwara N; Seki A; Gong Q; Zhou Z; Imamura S; Nagashima H; Kasanuki H; Takao A; Momma K; January CT; Robertson GA; Matsuoka R
Circulation; 1999 May; 99(17):2290-4. PubMed ID: 10226095
[TBL] [Abstract][Full Text] [Related]
8. Trafficking defect and proteasomal degradation contribute to the phenotype of a novel KCNH2 long QT syndrome mutation.
Mihic A; Chauhan VS; Gao X; Oudit GY; Tsushima RG
PLoS One; 2011 Mar; 6(3):e18273. PubMed ID: 21483829
[TBL] [Abstract][Full Text] [Related]
9. Trafficking-deficient hERG K⁺ channels linked to long QT syndrome are regulated by a microtubule-dependent quality control compartment in the ER.
Smith JL; McBride CM; Nataraj PS; Bartos DC; January CT; Delisle BP
Am J Physiol Cell Physiol; 2011 Jul; 301(1):C75-85. PubMed ID: 21490315
[TBL] [Abstract][Full Text] [Related]
10. Pharmacologic Approach to Defective Protein Trafficking in the E637K-hERG Mutant with PD-118057 and Thapsigargin.
Mao H; Lu X; Karush JM; Huang X; Yang X; Ba Y; Wang Y; Liu N; Zhou J; Lian J
PLoS One; 2013; 8(6):e65481. PubMed ID: 23840331
[TBL] [Abstract][Full Text] [Related]
11. Defective assembly and trafficking of mutant HERG channels with C-terminal truncations in long QT syndrome.
Gong Q; Keeney DR; Robinson JC; Zhou Z
J Mol Cell Cardiol; 2004 Dec; 37(6):1225-33. PubMed ID: 15572053
[TBL] [Abstract][Full Text] [Related]
12. Identification and functional characterization of the human ether-a-go-go-related gene Q738X mutant associated with hereditary long QT syndrome type 2.
Han SN; Yang SH; Zhang Y; Sun XY; Duan YY; Hu XJ; Fan TL; Huang CZ; Yang G; Zhang Z; Zhang L
Int J Mol Med; 2014 Sep; 34(3):810-5. PubMed ID: 24993425
[TBL] [Abstract][Full Text] [Related]
13. Trafficking-deficient G572R-hERG and E637K-hERG activate stress and clearance pathways in endoplasmic reticulum.
Wang Y; Huang X; Zhou J; Yang X; Li D; Mao H; Sun HH; Liu N; Lian J
PLoS One; 2012; 7(1):e29885. PubMed ID: 22242185
[TBL] [Abstract][Full Text] [Related]
14. HERG mutation predicts short QT based on channel kinetics but causes long QT by heterotetrameric trafficking deficiency.
Paulussen AD; Raes A; Jongbloed RJ; Gilissen RA; Wilde AA; Snyders DJ; Smeets HJ; Aerssens J
Cardiovasc Res; 2005 Aug; 67(3):467-75. PubMed ID: 15958262
[TBL] [Abstract][Full Text] [Related]
15. [Progress in research on defective protein trafficking and functional restoration in HERG-associated long QT syndrome].
Fang P; Lian J
Zhonghua Yi Xue Yi Chuan Xue Za Zhi; 2016 Feb; 33(1):101-4. PubMed ID: 26829745
[TBL] [Abstract][Full Text] [Related]
16. Correction of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effects.
Zhou Z; Gong Q; January CT
J Biol Chem; 1999 Oct; 274(44):31123-6. PubMed ID: 10531299
[TBL] [Abstract][Full Text] [Related]
17. Pharmacological correction of long QT-linked mutations in KCNH2 (hERG) increases the trafficking of Kv11.1 channels stored in the transitional endoplasmic reticulum.
Smith JL; Reloj AR; Nataraj PS; Bartos DC; Schroder EA; Moss AJ; Ohno S; Horie M; Anderson CL; January CT; Delisle BP
Am J Physiol Cell Physiol; 2013 Nov; 305(9):C919-30. PubMed ID: 23864605
[TBL] [Abstract][Full Text] [Related]
18. LQT2 nonsense mutations generate trafficking defective NH2-terminally truncated channels by the reinitiation of translation.
Stump MR; Gong Q; Zhou Z
Am J Physiol Heart Circ Physiol; 2013 Nov; 305(9):H1397-404. PubMed ID: 23997099
[TBL] [Abstract][Full Text] [Related]
19. Identification and functional characterization of the novel human ether-a-go-go-related gene (hERG) R744P mutant associated with hereditary long QT syndrome 2.
Aidery P; Kisselbach J; Gaspar H; Baldea I; Schweizer PA; Becker R; Katus HA; Thomas D
Biochem Biophys Res Commun; 2012 Feb; 418(4):830-5. PubMed ID: 22314138
[TBL] [Abstract][Full Text] [Related]
20. Mechanism of loss of Kv11.1 K+ current in mutant T421M-Kv11.1-expressing rat ventricular myocytes: interaction of trafficking and gating.
Balijepalli SY; Lim E; Concannon SP; Chew CL; Holzem KE; Tester DJ; Ackerman MJ; Delisle BP; Balijepalli RC; January CT
Circulation; 2012 Dec; 126(24):2809-18. PubMed ID: 23136156
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
