BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

161 related articles for article (PubMed ID: 20932552)

  • 1. Evaluation of the noncovalent binding interactions between polycyclic aromatic hydrocarbon metabolites and human p53 cDNA.
    Wei Y; Lin Y; Zhang AQ; Guo LH; Cao J
    Sci Total Environ; 2010 Nov; 408(24):6285-90. PubMed ID: 20932552
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential c-myc expression profiles in normal human bronchial epithelial cells following treatment with benzo[a]pyrene, benzo[a]pyrene-4,5 epoxide, and benzo[a]pyrene-7,8-9,10 diol epoxide.
    Fields WR; Desiderio JG; Leonard RM; Burger EE; Brown BG; Doolittle DJ
    Mol Carcinog; 2004 Jun; 40(2):79-89. PubMed ID: 15170813
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Comparison of p53 mutations induced by PAH o-quinones with those caused by anti-benzo[a]pyrene diol epoxide in vitro: role of reactive oxygen and biological selection.
    Shen YM; Troxel AB; Vedantam S; Penning TM; Field J
    Chem Res Toxicol; 2006 Nov; 19(11):1441-50. PubMed ID: 17112231
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Polycyclic aromatic hydrocarbons: 15 Listings - benz[a]anthracene, benzo[b]fluoranthene, benzo[j]fluoranthene, benzo[k]fluoranthene, benzo[a]pyrene, dibenz[a,h]acridine, dibenz[a,j]acridine, dibenz[a,h]anthracene, 7H-dibenzo[c,g]carbazole, dibenzo[a,e]pyrene, dibenzo[a,h]pyrene, dibenzo[a,i]pyrene, dibenzo[a,l]pyrene, indeno[1,2,3-cd]pyrene, 5-methylchrysene.
    National Toxicology Program
    Rep Carcinog; 2011; 12():353-61. PubMed ID: 21863085
    [No Abstract]   [Full Text] [Related]  

  • 5. Role and interaction of p53, BAX and the stress-activated protein kinases p38 and JNK in benzo(a)pyrene-diolepoxide induced apoptosis in human colon carcinoma cells.
    Donauer J; Schreck I; Liebel U; Weiss C
    Arch Toxicol; 2012 Feb; 86(2):329-37. PubMed ID: 21983885
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Disposition and biological activity of benzo[a]pyrene-7,8-dione. A genotoxic metabolite generated by dihydrodiol dehydrogenase.
    Flowers L; Bleczinski WF; Burczynski ME; Harvey RG; Penning TM
    Biochemistry; 1996 Oct; 35(42):13664-72. PubMed ID: 8885846
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression of human glutathione S-transferase P1 confers resistance to benzo[a]pyrene or benzo[a]pyrene-7,8-dihydrodiol mutagenesis, macromolecular alkylation and formation of stable N2-Gua-BPDE adducts in stably transfected V79MZ cells co-expressing hCYP1A1.
    Kushman ME; Kabler SL; Fleming MH; Ravoori S; Gupta RC; Doehmer J; Morrow CS; Townsend AJ
    Carcinogenesis; 2007 Jan; 28(1):207-14. PubMed ID: 16885195
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Determination of polycyclic aromatic hydrocarbons in the urine, benzo(a)pyrene diol epoxide-DNA adducts in lymphocyte DNA, and antibodies to the adducts in sera from coke oven workers exposed to measured amounts of polycyclic aromatic hydrocarbons in the work atmosphere.
    Haugen A; Becher G; Benestad C; Vahakangas K; Trivers GE; Newman MJ; Harris CC
    Cancer Res; 1986 Aug; 46(8):4178-83. PubMed ID: 3731085
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Spectral differentiation and immunoaffinity capillary electrophoresis separation of enantiomeric benzo(a)pyrene diol epoxide-derived DNA adducts.
    Miksa B; Chinnappan R; Dang NC; Reppert M; Matter B; Tretyakova N; Grubor NM; Jankowiak R
    Chem Res Toxicol; 2007 Aug; 20(8):1192-9. PubMed ID: 17630708
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Solution conformation of the (-)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove.
    Feng B; Gorin A; Kolbanovskiy A; Hingerty BE; Geacintov NE; Broyde S; Patel DJ
    Biochemistry; 1997 Nov; 36(45):13780-90. PubMed ID: 9374854
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Solution structure of the (+)-cis-anti-benzo[a]pyrene-dA ([BP]dA) adduct opposite dT in a DNA duplex.
    Mao B; Gu Z; Gorin A; Chen J; Hingerty BE; Amin S; Broyde S; Geacintov NE; Patel DJ
    Biochemistry; 1999 Aug; 38(33):10831-42. PubMed ID: 10451380
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of DNA adducts from lung tissue of asphalt fume-exposed mice by nanoflow liquid chromatography quadrupole time-of-flight mass spectrometry.
    Wang JJ; Marshall WD; Frazer DG; Law B; Lewis DM
    Anal Biochem; 2003 Nov; 322(1):79-88. PubMed ID: 14705783
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Production of polycyclic aromatic hydrocarbon metabolites from a peroxynitrite/iron(III) porphyrin biomimetic model and their mutagenicities.
    Luo Y; Dai J; Zhong R; She Y; Liu R; Wei H
    Environ Toxicol Chem; 2011 Mar; 30(3):723-9. PubMed ID: 21298714
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Reactive oxygen species generated by PAH o-quinones cause change-in-function mutations in p53.
    Yu D; Berlin JA; Penning TM; Field J
    Chem Res Toxicol; 2002 Jun; 15(6):832-42. PubMed ID: 12067251
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The pattern of p53 mutations caused by PAH o-quinones is driven by 8-oxo-dGuo formation while the spectrum of mutations is determined by biological selection for dominance.
    Park JH; Gelhaus S; Vedantam S; Oliva AL; Batra A; Blair IA; Troxel AB; Field J; Penning TM
    Chem Res Toxicol; 2008 May; 21(5):1039-49. PubMed ID: 18489080
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Repair of DNA lesions induced by polycyclic aromatic hydrocarbons in human cell-free extracts: involvement of two excision repair mechanisms in vitro.
    Braithwaite E; Wu X; Wang Z
    Carcinogenesis; 1998 Jul; 19(7):1239-46. PubMed ID: 9683183
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lack of contribution of covalent benzo[a]pyrene-7,8-quinone-DNA adducts in benzo[a]pyrene-induced mouse lung tumorigenesis.
    Nesnow S; Nelson G; Padgett WT; George MH; Moore T; King LC; Adams LD; Ross JA
    Chem Biol Interact; 2010 Jul; 186(2):157-65. PubMed ID: 20346927
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Benzo[a]pyrene-induced DNA damage and p53 modulation in human hepatoma HepG2 cells for the identification of potential biomarkers for PAH monitoring and risk assessment.
    Park SY; Lee SM; Ye SK; Yoon SH; Chung MH; Choi J
    Toxicol Lett; 2006 Nov; 167(1):27-33. PubMed ID: 17029827
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Polycyclic aromatic hydrocarbon (PAH) metabolizing enzyme activities in human lung, and their inducibility by exposure to naphthalene, phenanthrene, pyrene, chrysene, and benzo(a)pyrene as shown in the rat lung and liver.
    Elovaara E; Mikkola J; Stockmann-Juvala H; Luukkanen L; Keski-Hynnilä H; Kostiainen R; Pasanen M; Pelkonen O; Vainio H
    Arch Toxicol; 2007 Mar; 81(3):169-82. PubMed ID: 16906435
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Correlation between biomarkers of polycyclic aromatic hydrocarbon exposure and electrophilic tissue burden in a rat model.
    Tzekova A; Thuot R; Viau C
    Arch Toxicol; 2004 Jun; 78(6):351-61. PubMed ID: 14749914
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.