These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

101 related articles for article (PubMed ID: 20932609)

  • 1. Synthesis of novel chiral Δ2-isoxazoline derivatives related to ABT-418 and estimation of their affinity at neuronal nicotinic acetylcholine receptor subtypes.
    Dallanoce C; Magrone P; Matera C; Lo Presti L; De Amici M; Riganti L; Clementi F; Gotti C; De Micheli C
    Eur J Med Chem; 2010 Dec; 45(12):5594-601. PubMed ID: 20932609
    [TBL] [Abstract][Full Text] [Related]  

  • 2. New spirocyclic Δ²-isoxazoline derivatives related to selective agonists of α7 neuronal nicotinic acetylcholine receptors.
    Dallanoce C; Frigerio F; Grazioso G; Matera C; Visconti GL; De Amici M; Pucci L; Pistillo F; Fucile S; Gotti C; Clementi F; De Micheli C
    Eur J Med Chem; 2011 Dec; 46(12):5790-9. PubMed ID: 22014558
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis, and pharmacological characterization of novel spirocyclic quinuclidinyl-Δ2-isoxazoline derivatives as potent and selective agonists of α7 nicotinic acetylcholine receptors.
    Dallanoce C; Magrone P; Matera C; Frigerio F; Grazioso G; De Amici M; Fucile S; Piccari V; Frydenvang K; Pucci L; Gotti C; Clementi F; De Micheli C
    ChemMedChem; 2011 May; 6(5):889-903. PubMed ID: 21365765
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The enantiomers of epiboxidine and of two related analogs: synthesis and estimation of their binding affinity at α4β2 and α7 neuronal nicotinic acetylcholine receptors.
    Dallanoce C; Matera C; De Amici M; Rizzi L; Pucci L; Gotti C; Clementi F; De Micheli C
    Chirality; 2012 Jul; 24(7):543-51. PubMed ID: 22566097
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Epiboxidine and novel-related analogues: a convenient synthetic approach and estimation of their affinity at neuronal nicotinic acetylcholine receptor subtypes.
    Rizzi L; Dallanoce C; Matera C; Magrone P; Pucci L; Gotti C; Clementi F; De Amici M
    Bioorg Med Chem Lett; 2008 Aug; 18(16):4651-4. PubMed ID: 18644719
    [TBL] [Abstract][Full Text] [Related]  

  • 6. New analogues of epiboxidine incorporating the 4,5-dihydroisoxazole nucleus: synthesis, binding affinity at neuronal nicotinic acetylcholine receptors, and molecular modeling investigations.
    Dallanoce C; Magrone P; Bazza P; Grazioso G; Rizzi L; Riganti L; Gotti C; Clementi F; Frydenvang K; De Amici M
    Chem Biodivers; 2009 Feb; 6(2):244-59. PubMed ID: 19235154
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel tricyclic Delta(2)-isoxazoline and 3-oxo-2-methyl-isoxazolidine derivatives: synthesis and binding affinity at neuronal nicotinic acetylcholine receptor subtypes.
    Dallanoce C; Frigerio F; Martelli G; Grazioso G; Matera C; Pomè DY; Pucci L; Clementi F; Gotti C; De Amici M
    Bioorg Med Chem; 2010 Jun; 18(12):4498-508. PubMed ID: 20478710
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis of enantiopure Delta2-isoxazoline derivatives and evaluation of their affinity and efficacy profiles at human beta-adrenergic receptor subtypes.
    Dallanoce C; Meroni G; De Amici M; Hoffmann C; Klotz KN; De Micheli C
    Bioorg Med Chem; 2006 Jul; 14(13):4393-401. PubMed ID: 16530417
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vitro pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107.
    Malysz J; Anderson DJ; Grønlien JH; Ji J; Bunnelle WH; Håkerud M; Thorin-Hagene K; Ween H; Helfrich R; Hu M; Gubbins E; Gopalakrishnan S; Puttfarcken PS; Briggs CA; Li J; Meyer MD; Dyhring T; Ahring PK; Nielsen EØ; Peters D; Timmermann DB; Gopalakrishnan M
    J Pharmacol Exp Ther; 2010 Sep; 334(3):863-74. PubMed ID: 20504915
    [TBL] [Abstract][Full Text] [Related]  

  • 10. (5'S)- and (5'R)-5',8-cyclo-2'-deoxyguanosine: mechanistic insights on the 2'-deoxyguanosin-5'-yl radical cyclization.
    Chatgilialoglu C; Bazzanini R; Jimenez LB; Miranda MA
    Chem Res Toxicol; 2007 Dec; 20(12):1820-4. PubMed ID: 17988100
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-activity studies on 2-methyl-3-(2(S)-pyrrolidinylmethoxy) pyridine (ABT-089): an orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties.
    Lin NH; Gunn DE; Ryther KB; Garvey DS; Donnelly-Roberts DL; Decker MW; Brioni JD; Buckley MJ; Rodrigues AD; Marsh KG; Anderson DJ; Buccafusco JJ; Prendergast MA; Sullivan JP; Williams M; Arneric SP; Holladay MW
    J Med Chem; 1997 Jan; 40(3):385-90. PubMed ID: 9022806
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 5-substituted derivatives of 6-halogeno-3-((2-(S)-azetidinyl)methoxy)pyridine and 6-halogeno-3-((2-(S)-pyrrolidinyl)methoxy)pyridine with low picomolar affinity for alpha4beta2 nicotinic acetylcholine receptor and wide range of lipophilicity: potential probes for imaging with positron emission tomography.
    Zhang Y; Pavlova OA; Chefer SI; Hall AW; Kurian V; Brown LL; Kimes AS; Mukhin AG; Horti AG
    J Med Chem; 2004 May; 47(10):2453-65. PubMed ID: 15115389
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design of novel alpha7-subtype-preferring nicotinic acetylcholine receptor agonists: application of docking and MM-PBSA computational approaches, synthetic and pharmacological studies.
    Grazioso G; Pomè DY; Matera C; Frigerio F; Pucci L; Gotti C; Dallanoce C; De Amici M
    Bioorg Med Chem Lett; 2009 Nov; 19(22):6353-7. PubMed ID: 19804970
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Facile synthetic route to enantiopure unsymmetric cis-2,5-disubstituted pyrrolidines.
    Wang PA; Xu ZS; Chen CF; Gao XG; Sun XL; Zhang SY
    Chirality; 2007 Jul; 19(7):581-8. PubMed ID: 17508396
    [TBL] [Abstract][Full Text] [Related]  

  • 15. (S)-3-methyl-5-(1-methyl-2-pyrrolidinyl) isoxazole (ABT 418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: I. In vitro characterization.
    Arneric SP; Sullivan JP; Briggs CA; Donnelly-Roberts D; Anderson DJ; Raszkiewicz JL; Hughes ML; Cadman ED; Adams P; Garvey DS
    J Pharmacol Exp Ther; 1994 Jul; 270(1):310-8. PubMed ID: 7518514
    [TBL] [Abstract][Full Text] [Related]  

  • 16. N-n-alkylnicotinium analogs, a novel class of nicotinic receptor antagonists: interaction with alpha4beta2* and alpha7* neuronal nicotinic receptors.
    Wilkins LH; Grinevich VP; Ayers JT; Crooks PA; Dwoskin LP
    J Pharmacol Exp Ther; 2003 Jan; 304(1):400-10. PubMed ID: 12490617
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel chiral isoxazole derivatives: synthesis and pharmacological characterization at human beta-adrenergic receptor subtypes.
    Dallanoce C; Frigerio F; De Amici M; Dorsch S; Klotz KN; De Micheli C
    Bioorg Med Chem; 2007 Apr; 15(7):2533-43. PubMed ID: 17303428
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel acetylcholine and carbamoylcholine analogues: development of a functionally selective alpha4beta2 nicotinic acetylcholine receptor agonist.
    Hansen CP; Jensen AA; Christensen JK; Balle T; Liljefors T; Frølund B
    J Med Chem; 2008 Dec; 51(23):7380-95. PubMed ID: 18989912
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Characterization of [3H]ABT-418: a novel cholinergic channel ligand.
    Anderson DJ; Williams M; Pauly JR; Raszkiewicz JL; Campbell JE; Rotert G; Surber B; Thomas SB; Wasicak J; Arneric SP
    J Pharmacol Exp Ther; 1995 Jun; 273(3):1434-41. PubMed ID: 7791118
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis, and preliminary pharmacological evaluation of new quinoline derivatives as nicotinic ligands.
    Guandalini L; Norcini M; Varani K; Pistolozzi M; Gotti C; Bazzicalupi C; Martini E; Dei S; Manetti D; Scapecchi S; Teodori E; Bertucci C; Ghelardini C; Romanelli MN
    J Med Chem; 2007 Oct; 50(20):4993-5002. PubMed ID: 17850058
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.