BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 20933082)

  • 1. Garlic extract induces intestinal P-glycoprotein, but exhibits no effect on intestinal and hepatic CYP3A4 in humans.
    Hajda J; Rentsch KM; Gubler C; Steinert H; Stieger B; Fattinger K
    Eur J Pharm Sci; 2010 Dec; 41(5):729-35. PubMed ID: 20933082
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Variation in oral clearance of saquinavir is predicted by CYP3A5*1 genotype but not by enterocyte content of cytochrome P450 3A5.
    Mouly SJ; Matheny C; Paine MF; Smith G; Lamba J; Lamba V; Pusek SN; Schuetz EG; Stewart PW; Watkins PB
    Clin Pharmacol Ther; 2005 Dec; 78(6):605-18. PubMed ID: 16338276
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanisms of pharmacokinetic enhancement between ritonavir and saquinavir; micro/small dosing tests using midazolam (CYP3A4), fexofenadine (p-glycoprotein), and pravastatin (OATP1B1) as probe drugs.
    Ieiri I; Tsunemitsu S; Maeda K; Ando Y; Izumi N; Kimura M; Yamane N; Okuzono T; Morishita M; Kotani N; Kanda E; Deguchi M; Matsuguma K; Matsuki S; Hirota T; Irie S; Kusuhara H; Sugiyama Y
    J Clin Pharmacol; 2013 Jun; 53(6):654-61. PubMed ID: 23381882
    [TBL] [Abstract][Full Text] [Related]  

  • 4. St John's Wort induces intestinal P-glycoprotein/MDR1 and intestinal and hepatic CYP3A4.
    Dürr D; Stieger B; Kullak-Ublick GA; Rentsch KM; Steinert HC; Meier PJ; Fattinger K
    Clin Pharmacol Ther; 2000 Dec; 68(6):598-604. PubMed ID: 11180019
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Garlic flavonoids and organosulfur compounds: impact on the hepatic pharmacokinetics of saquinavir and darunavir.
    Berginc K; Milisav I; Kristl A
    Drug Metab Pharmacokinet; 2010; 25(6):521-30. PubMed ID: 20930421
    [TBL] [Abstract][Full Text] [Related]  

  • 6. HIV protease inhibitors: garlic supplements and first-pass intestinal metabolism impact on the therapeutic efficacy.
    Berginc K; Trdan T; Trontelj J; Kristl A
    Biopharm Drug Dispos; 2010 Nov; 31(8-9):495-505. PubMed ID: 21104925
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cytochrome P450 3A4 and P-glycoprotein expression in human small intestinal enterocytes and hepatocytes: a comparative analysis in paired tissue specimens.
    von Richter O; Burk O; Fromm MF; Thon KP; Eichelbaum M; Kivistö KT
    Clin Pharmacol Ther; 2004 Mar; 75(3):172-83. PubMed ID: 15001968
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of ursodeoxycholic acid on P-glycoprotein and cytochrome P450 3A4-dependent pharmacokinetics in humans.
    Becquemont L; Glaeser H; Drescher S; Hitzl M; Simon N; Murdter TE; Heinkele G; Hofmann U; Schaefer C; Burk O; Verstuyft C; Eichelbaum M; Fromm MF
    Clin Pharmacol Ther; 2006 May; 79(5):449-60. PubMed ID: 16678547
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The influence of aged garlic extract on the uptake of saquinavir and darunavir into HepG2 cells and rat liver slices.
    Berginc K; Trontelj J; Kristl A
    Drug Metab Pharmacokinet; 2010; 25(3):307-13. PubMed ID: 20610890
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hypericum perforatum: which constituents may induce intestinal MDR1 and CYP3A4 mRNA expression?
    Gutmann H; Poller B; Büter KB; Pfrunder A; Schaffner W; Drewe J
    Planta Med; 2006 Jun; 72(8):685-90. PubMed ID: 16755466
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evaluation of memory enhancing clinically available standardized extract of Bacopa monniera on P-glycoprotein and cytochrome P450 3A in Sprague-Dawley rats.
    Singh R; Panduri J; Kumar D; Kumar D; Chandsana H; Ramakrishna R; Bhatta RS
    PLoS One; 2013; 8(8):e72517. PubMed ID: 24015255
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of Curcuma extracts and curcuminoids on expression of P-glycoprotein and cytochrome P450 3A4 in the intestinal cell culture model LS180.
    Graber-Maier A; Büter KB; Aeschlimann J; Bittel C; Kreuter M; Drewe J; Gutmann H
    Planta Med; 2010 Nov; 76(16):1866-70. PubMed ID: 20509107
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cytochrome P450 3A4 and P-glycoprotein mediate the interaction between an oral erythromycin breath test and rifampin.
    Paine MF; Wagner DA; Hoffmaster KA; Watkins PB
    Clin Pharmacol Ther; 2002 Nov; 72(5):524-35. PubMed ID: 12426516
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of variations in the amounts of P-glycoprotein (ABCB1), BCRP (ABCG2) and CYP3A4 along the human small intestine on PBPK models for predicting intestinal first pass.
    Bruyère A; Declèves X; Bouzom F; Ball K; Marques C; Treton X; Pocard M; Valleur P; Bouhnik Y; Panis Y; Scherrmann JM; Mouly S
    Mol Pharm; 2010 Oct; 7(5):1596-607. PubMed ID: 20604570
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modulation of human cytochrome P450 3A4 (CYP3A4) and P-glycoprotein (P-gp) in Caco-2 cell monolayers by selected commercial-source milk thistle and goldenseal products.
    Budzinski JW; Trudeau VL; Drouin CE; Panahi M; Arnason JT; Foster BC
    Can J Physiol Pharmacol; 2007 Sep; 85(9):966-78. PubMed ID: 18066144
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of lovastatin on the pharmacokinetics of diltiazem and its main metabolite, desacetyldiltiazem, in rats: possible role of cytochrome P450 3A4 and P-glycoprotein inhibition by lovastatin.
    Hong SP; Yang JS; Han JY; Ha SI; Chung JW; Koh YY; Chang KS; Choi DH
    J Pharm Pharmacol; 2011 Jan; 63(1):129-35. PubMed ID: 21189658
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The mechanisms responsible for garlic - drug interactions and their in vivo relevance.
    Berginc K; Kristl A
    Curr Drug Metab; 2013 Jan; 14(1):90-101. PubMed ID: 21838705
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Involvement of cytochrome P450 3A4 and P-glycoprotein in first-pass intestinal extraction of omeprazole in rabbits.
    Fang HM; Xu JM; Mei Q; Diao L; Chen ML; Jin J; Xu XH
    Acta Pharmacol Sin; 2009 Nov; 30(11):1566-72. PubMed ID: 19820718
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Alterations of CYP3A4 and P-glycoprotein activity in vivo with time in renal graft recipients.
    Lemahieu WP; Maes BD; Verbeke K; Vanrenterghem YF
    Kidney Int; 2004 Jul; 66(1):433-40. PubMed ID: 15200453
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of garlic (Allium sativum L.) supplementation on cytochrome P450 2D6 and 3A4 activity in healthy volunteers.
    Markowitz JS; Devane CL; Chavin KD; Taylor RM; Ruan Y; Donovan JL
    Clin Pharmacol Ther; 2003 Aug; 74(2):170-7. PubMed ID: 12891227
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.