398 related articles for article (PubMed ID: 20933468)
1. The role of conformational ensembles of seven transmembrane receptors in functional selectivity.
Vaidehi N; Kenakin T
Curr Opin Pharmacol; 2010 Dec; 10(6):775-81. PubMed ID: 20933468
[TBL] [Abstract][Full Text] [Related]
2. Conformational complexity of G-protein-coupled receptors.
Kobilka BK; Deupi X
Trends Pharmacol Sci; 2007 Aug; 28(8):397-406. PubMed ID: 17629961
[TBL] [Abstract][Full Text] [Related]
3. Agonist-induced conformational changes in bovine rhodopsin: insight into activation of G-protein-coupled receptors.
Bhattacharya S; Hall SE; Vaidehi N
J Mol Biol; 2008 Oct; 382(2):539-55. PubMed ID: 18638482
[TBL] [Abstract][Full Text] [Related]
4. The role of conformational ensembles in ligand recognition in G-protein coupled receptors.
Niesen MJ; Bhattacharya S; Vaidehi N
J Am Chem Soc; 2011 Aug; 133(33):13197-204. PubMed ID: 21766860
[TBL] [Abstract][Full Text] [Related]
5. Collateral efficacy in drug discovery: taking advantage of the good (allosteric) nature of 7TM receptors.
Kenakin T
Trends Pharmacol Sci; 2007 Aug; 28(8):407-15. PubMed ID: 17629960
[TBL] [Abstract][Full Text] [Related]
6. Molecular dynamics simulations of the effect of the G-protein and diffusible ligands on the β2-adrenergic receptor.
Goetz A; Lanig H; Gmeiner P; Clark T
J Mol Biol; 2011 Dec; 414(4):611-23. PubMed ID: 22037586
[TBL] [Abstract][Full Text] [Related]
7. Structural basis for ligand binding and specificity in adrenergic receptors: implications for GPCR-targeted drug discovery.
Huber T; Menon S; Sakmar TP
Biochemistry; 2008 Oct; 47(42):11013-23. PubMed ID: 18821775
[TBL] [Abstract][Full Text] [Related]
8. Switching modes for G protein-coupled receptor activation.
Vilardaga JP
Nat Chem Biol; 2006 Aug; 2(8):395-6. PubMed ID: 16850011
[No Abstract] [Full Text] [Related]
9. When simple agonism is not enough: emerging modalities of GPCR ligands.
Smith NJ; Bennett KA; Milligan G
Mol Cell Endocrinol; 2011 Jan; 331(2):241-7. PubMed ID: 20654693
[TBL] [Abstract][Full Text] [Related]
10. G protein coupled receptors as allosteric proteins and the role of allosteric modulators.
Kenakin T
J Recept Signal Transduct Res; 2010 Oct; 30(5):313-21. PubMed ID: 20858023
[TBL] [Abstract][Full Text] [Related]
11. Ligand- and heterodimer-directed signaling of the CB(1) cannabinoid receptor.
Hudson BD; Hébert TE; Kelly ME
Mol Pharmacol; 2010 Jan; 77(1):1-9. PubMed ID: 19837905
[TBL] [Abstract][Full Text] [Related]
12. Versatility of GPCR recognition by drugs: from biological implications to therapeutic relevance.
Bosier B; Hermans E
Trends Pharmacol Sci; 2007 Aug; 28(8):438-46. PubMed ID: 17629964
[TBL] [Abstract][Full Text] [Related]
13. Inverse agonists: tools to reveal ligand-specific conformations of G protein-coupled receptors.
Prather PL
Sci STKE; 2004 Jan; 2004(215):pe1. PubMed ID: 14722344
[TBL] [Abstract][Full Text] [Related]
14. Molecular dynamics of a biophysical model for beta2-adrenergic and G protein-coupled receptor activation.
Rubenstein LA; Zauhar RJ; Lanzara RG
J Mol Graph Model; 2006 Dec; 25(4):396-409. PubMed ID: 16574446
[TBL] [Abstract][Full Text] [Related]
15. Conformational rearrangements and signaling cascades involved in ligand-biased mitogen-activated protein kinase signaling through the beta1-adrenergic receptor.
Galandrin S; Oligny-Longpré G; Bonin H; Ogawa K; Galés C; Bouvier M
Mol Pharmacol; 2008 Jul; 74(1):162-72. PubMed ID: 18403719
[TBL] [Abstract][Full Text] [Related]
16. Distinct signaling profiles of beta1 and beta2 adrenergic receptor ligands toward adenylyl cyclase and mitogen-activated protein kinase reveals the pluridimensionality of efficacy.
Galandrin S; Bouvier M
Mol Pharmacol; 2006 Nov; 70(5):1575-84. PubMed ID: 16901982
[TBL] [Abstract][Full Text] [Related]
17. Insights into signaling from the beta2-adrenergic receptor structure.
Audet M; Bouvier M
Nat Chem Biol; 2008 Jul; 4(7):397-403. PubMed ID: 18560432
[TBL] [Abstract][Full Text] [Related]
18. Membrane signalling complexes: implications for development of functionally selective ligands modulating heptahelical receptor signalling.
Piñeyro G
Cell Signal; 2009 Feb; 21(2):179-85. PubMed ID: 18790047
[TBL] [Abstract][Full Text] [Related]
19. Functional selectivity through protean and biased agonism: who steers the ship?
Kenakin T
Mol Pharmacol; 2007 Dec; 72(6):1393-401. PubMed ID: 17901198
[TBL] [Abstract][Full Text] [Related]
20. Functional differences between full and partial agonists: evidence for ligand-specific receptor conformations.
Seifert R; Wenzel-Seifert K; Gether U; Kobilka BK
J Pharmacol Exp Ther; 2001 Jun; 297(3):1218-26. PubMed ID: 11356949
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
