BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

284 related articles for article (PubMed ID: 20934403)

  • 1. TGFβ induces proHB-EGF shedding and EGFR transactivation through ADAM activation in gastric cancer cells.
    Ebi M; Kataoka H; Shimura T; Kubota E; Hirata Y; Mizushima T; Mizoshita T; Tanaka M; Mabuchi M; Tsukamoto H; Tanida S; Kamiya T; Higashiyama S; Joh T
    Biochem Biophys Res Commun; 2010 Nov; 402(3):449-54. PubMed ID: 20934403
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Suppression of proHB-EGF carboxy-terminal fragment nuclear translocation: a new molecular target therapy for gastric cancer.
    Shimura T; Kataoka H; Ogasawara N; Kubota E; Sasaki M; Tanida S; Joh T
    Clin Cancer Res; 2008 Jun; 14(12):3956-65. PubMed ID: 18559618
    [TBL] [Abstract][Full Text] [Related]  

  • 3. HB-EGF release mediates glucose-induced activation of the epidermal growth factor receptor in mesangial cells.
    Uttarwar L; Peng F; Wu D; Kumar S; Gao B; Ingram AJ; Krepinsky JC
    Am J Physiol Renal Physiol; 2011 Apr; 300(4):F921-31. PubMed ID: 21289053
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Telmisartan inhibits cell proliferation by blocking nuclear translocation of ProHB-EGF C-terminal fragment in colon cancer cells.
    Ozeki K; Tanida S; Morimoto C; Inoue Y; Mizoshita T; Tsukamoto H; Shimura T; Kataoka H; Kamiya T; Nishiwaki E; Ishiguro H; Higashiyama S; Joh T
    PLoS One; 2013; 8(2):e56770. PubMed ID: 23451083
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nuclear translocation of the cytoplasmic domain of HB-EGF induces gastric cancer invasion.
    Shimura T; Yoshida M; Fukuda S; Ebi M; Hirata Y; Mizoshita T; Tanida S; Kataoka H; Kamiya T; Higashiyama S; Joh T
    BMC Cancer; 2012 May; 12():205. PubMed ID: 22646534
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Insulin-induced ectodomain shedding of heparin-binding epidermal growth factor-like growth factor in adipocytes in vitro.
    Yamamoto T; Suganami T; Kiso-Narita M; Scherle PA; Kamei Y; Isobe M; Higashiyama S; Ogawa Y
    Obesity (Silver Spring); 2010 Oct; 18(10):1888-94. PubMed ID: 20111015
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Clinical significance of heparin-binding epidermal growth factor-like growth factor and a disintegrin and metalloprotease 17 expression in human ovarian cancer.
    Tanaka Y; Miyamoto S; Suzuki SO; Oki E; Yagi H; Sonoda K; Yamazaki A; Mizushima H; Maehara Y; Mekada E; Nakano H
    Clin Cancer Res; 2005 Jul; 11(13):4783-92. PubMed ID: 16000575
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ADAM-mediated ectodomain shedding of HB-EGF in receptor cross-talk.
    Higashiyama S; Nanba D
    Biochim Biophys Acta; 2005 Aug; 1751(1):110-7. PubMed ID: 16054021
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 5-HT2A receptor induces ERK phosphorylation and proliferation through ADAM-17 tumor necrosis factor-alpha-converting enzyme (TACE) activation and heparin-bound epidermal growth factor-like growth factor (HB-EGF) shedding in mesangial cells.
    Göőz M; Göőz P; Luttrell LM; Raymond JR
    J Biol Chem; 2006 Jul; 281(30):21004-21012. PubMed ID: 16737974
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A Lactobacillus rhamnosus GG-derived soluble protein, p40, stimulates ligand release from intestinal epithelial cells to transactivate epidermal growth factor receptor.
    Yan F; Liu L; Dempsey PJ; Tsai YH; Raines EW; Wilson CL; Cao H; Cao Z; Liu L; Polk DB
    J Biol Chem; 2013 Oct; 288(42):30742-30751. PubMed ID: 24043629
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ERK1/2 mediate wounding- and G-protein-coupled receptor ligands-induced EGFR activation via regulating ADAM17 and HB-EGF shedding.
    Yin J; Yu FS
    Invest Ophthalmol Vis Sci; 2009 Jan; 50(1):132-9. PubMed ID: 18658095
    [TBL] [Abstract][Full Text] [Related]  

  • 12. IL-8 promotes cell proliferation and migration through metalloproteinase-cleavage proHB-EGF in human colon carcinoma cells.
    Itoh Y; Joh T; Tanida S; Sasaki M; Kataoka H; Itoh K; Oshima T; Ogasawara N; Togawa S; Wada T; Kubota H; Mori Y; Ohara H; Nomura T; Higashiyama S; Itoh M
    Cytokine; 2005 Mar; 29(6):275-82. PubMed ID: 15749028
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transactivation of epidermal growth factor receptor after heparin-binding epidermal growth factor-like growth factor shedding in the migration of prostate cancer cells promoted by bombesin.
    Madarame J; Higashiyama S; Kiyota H; Madachi A; Toki F; Shimomura T; Tani N; Oishi Y; Matsuura N
    Prostate; 2003 Nov; 57(3):187-95. PubMed ID: 14518027
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Intranuclear translocation signaling of HB-EGF carboxy-terminal fragment and mucosal defense through cell proliferation and migration in digestive tracts.
    Tanida S; Kataoka H; Mizoshita T; Shimura T; Kamiya T; Joh T
    Digestion; 2010; 82(3):145-9. PubMed ID: 20588025
    [TBL] [Abstract][Full Text] [Related]  

  • 15. G protein coupling and second messenger generation are indispensable for metalloprotease-dependent, heparin-binding epidermal growth factor shedding through angiotensin II type-1 receptor.
    Mifune M; Ohtsu H; Suzuki H; Nakashima H; Brailoiu E; Dun NJ; Frank GD; Inagami T; Higashiyama S; Thomas WG; Eckhart AD; Dempsey PJ; Eguchi S
    J Biol Chem; 2005 Jul; 280(28):26592-9. PubMed ID: 15905175
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Wound-induced ATP release and EGF receptor activation in epithelial cells.
    Yin J; Xu K; Zhang J; Kumar A; Yu FS
    J Cell Sci; 2007 Mar; 120(Pt 5):815-25. PubMed ID: 17284517
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Insulin-induced epidermal growth factor activation in vascular smooth muscle cells is ADAM-dependent.
    Roztocil E; Nicholl SM; Davies MG
    Surgery; 2008 Aug; 144(2):245-51. PubMed ID: 18656632
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cell migration in response to the amino-terminal fragment of urokinase requires epidermal growth factor receptor activation through an ADAM-mediated mechanism.
    Bakken AM; Protack CD; Roztocil E; Nicholl SM; Davies MG
    J Vasc Surg; 2009 May; 49(5):1296-303. PubMed ID: 19394555
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ectodomain shedding of HB-EGF: a potential target for cancer therapy.
    Miyazono K
    J Biochem; 2012 Jan; 151(1):1-3. PubMed ID: 21976708
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Epithelial cell ADAM17 activation by Helicobacter pylori: role of ADAM17 C-terminus and Threonine-735 phosphorylation.
    McClurg UL; Danjo K; King HO; Scott GB; Robinson PA; Crabtree JE
    Microbes Infect; 2015 Mar; 17(3):205-14. PubMed ID: 25499189
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.