BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

234 related articles for article (PubMed ID: 20935071)

  • 1. Notch dimerization is required for leukemogenesis and T-cell development.
    Liu H; Chi AW; Arnett KL; Chiang MY; Xu L; Shestova O; Wang H; Li YM; Bhandoola A; Aster JC; Blacklow SC; Pear WS
    Genes Dev; 2010 Nov; 24(21):2395-407. PubMed ID: 20935071
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia.
    Yashiro-Ohtani Y; Wang H; Zang C; Arnett KL; Bailis W; Ho Y; Knoechel B; Lanauze C; Louis L; Forsyth KS; Chen S; Chung Y; Schug J; Blobel GA; Liebhaber SA; Bernstein BE; Blacklow SC; Liu XS; Aster JC; Pear WS
    Proc Natl Acad Sci U S A; 2014 Nov; 111(46):E4946-53. PubMed ID: 25369933
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Notch signaling expands a pre-malignant pool of T-cell acute lymphoblastic leukemia clones without affecting leukemia-propagating cell frequency.
    Blackburn JS; Liu S; Raiser DM; Martinez SA; Feng H; Meeker ND; Gentry J; Neuberg D; Look AT; Ramaswamy S; Bernards A; Trede NS; Langenau DM
    Leukemia; 2012 Sep; 26(9):2069-78. PubMed ID: 22538478
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DDX5 is a positive regulator of oncogenic NOTCH1 signaling in T cell acute lymphoblastic leukemia.
    Lin S; Tian L; Shen H; Gu Y; Li JL; Chen Z; Sun X; You MJ; Wu L
    Oncogene; 2013 Oct; 32(40):4845-53. PubMed ID: 23108395
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Oncogenesis of T-ALL and nonmalignant consequences of overexpressing intracellular NOTCH1.
    Li X; Gounari F; Protopopov A; Khazaie K; von Boehmer H
    J Exp Med; 2008 Nov; 205(12):2851-61. PubMed ID: 18981238
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Haploinsufficiency of the c-myc transcriptional repressor FIR, as a dominant negative-alternative splicing model, promoted p53-dependent T-cell acute lymphoblastic leukemia progression by activating Notch1.
    Matsushita K; Kitamura K; Rahmutulla B; Tanaka N; Ishige T; Satoh M; Hoshino T; Miyagi S; Mori T; Itoga S; Shimada H; Tomonaga T; Kito M; Nakajima-Takagi Y; Kubo S; Nakaseko C; Hatano M; Miki T; Matsuo M; Fukuyo M; Kaneda A; Iwama A; Nomura F
    Oncotarget; 2015 Mar; 6(7):5102-17. PubMed ID: 25671302
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Notch ankyrin repeat domain variation influences leukemogenesis and Myc transactivation.
    Aster JC; Bodnar N; Xu L; Karnell F; Milholland JM; Maillard I; Histen G; Nam Y; Blacklow SC; Pear WS
    PLoS One; 2011; 6(10):e25645. PubMed ID: 22022427
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The common oncogenomic program of NOTCH1 and NOTCH3 signaling in T-cell acute lymphoblastic leukemia.
    Choi SH; Severson E; Pear WS; Liu XS; Aster JC; Blacklow SC
    PLoS One; 2017; 12(10):e0185762. PubMed ID: 29023469
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors.
    Aste-Amézaga M; Zhang N; Lineberger JE; Arnold BA; Toner TJ; Gu M; Huang L; Vitelli S; Vo KT; Haytko P; Zhao JZ; Baleydier F; L'Heureux S; Wang H; Gordon WR; Thoryk E; Andrawes MB; Tiyanont K; Stegmaier K; Roti G; Ross KN; Franlin LL; Wang H; Wang F; Chastain M; Bett AJ; Audoly LP; Aster JC; Blacklow SC; Huber HE
    PLoS One; 2010 Feb; 5(2):e9094. PubMed ID: 20161710
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MAFB enhances oncogenic Notch signaling in T cell acute lymphoblastic leukemia.
    Pajcini KV; Xu L; Shao L; Petrovic J; Palasiewicz K; Ohtani Y; Bailis W; Lee C; Wertheim GB; Mani R; Muthusamy N; Li Y; Meijerink JPP; Blacklow SC; Faryabi RB; Cherry S; Pear WS
    Sci Signal; 2017 Nov; 10(505):. PubMed ID: 29138297
    [TBL] [Abstract][Full Text] [Related]  

  • 11. High selective pressure for Notch1 mutations that induce Myc in T-cell acute lymphoblastic leukemia.
    Chiang MY; Wang Q; Gormley AC; Stein SJ; Xu L; Shestova O; Aster JC; Pear WS
    Blood; 2016 Nov; 128(18):2229-2240. PubMed ID: 27670423
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Epigenetic regulation of the Ink4a-Arf (Cdkn2a) tumor suppressor locus in the initiation and progression of Notch1-driven T cell acute lymphoblastic leukemia.
    Volanakis EJ; Boothby MR; Sherr CJ
    Exp Hematol; 2013 Apr; 41(4):377-86. PubMed ID: 23178376
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Lunatic Fringe prolongs Delta/Notch-induced self-renewal of committed αβ T-cell progenitors.
    Yuan JS; Tan JB; Visan I; Matei IR; Urbanellis P; Xu K; Danska JS; Egan SE; Guidos CJ
    Blood; 2011 Jan; 117(4):1184-95. PubMed ID: 21097675
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The NOTCH1-MYC highway toward T-cell acute lymphoblastic leukemia.
    Sanchez-Martin M; Ferrando A
    Blood; 2017 Mar; 129(9):1124-1133. PubMed ID: 28115368
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia.
    Durinck K; Wallaert A; Van de Walle I; Van Loocke W; Volders PJ; Vanhauwaert S; Geerdens E; Benoit Y; Van Roy N; Poppe B; Soulier J; Cools J; Mestdagh P; Vandesompele J; Rondou P; Van Vlierberghe P; Taghon T; Speleman F
    Haematologica; 2014 Dec; 99(12):1808-16. PubMed ID: 25344525
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.
    Yatim A; Benne C; Sobhian B; Laurent-Chabalier S; Deas O; Judde JG; Lelievre JD; Levy Y; Benkirane M
    Mol Cell; 2012 Nov; 48(3):445-58. PubMed ID: 23022380
    [TBL] [Abstract][Full Text] [Related]  

  • 17. β-Catenin is required for T-cell leukemia initiation and MYC transcription downstream of Notch1.
    Gekas C; D'Altri T; Aligué R; González J; Espinosa L; Bigas A
    Leukemia; 2016 Oct; 30(10):2002-2010. PubMed ID: 27125305
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia.
    Vacca A; Felli MP; Palermo R; Di Mario G; Calce A; Di Giovine M; Frati L; Gulino A; Screpanti I
    EMBO J; 2006 Mar; 25(5):1000-8. PubMed ID: 16498412
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Notch1 inhibition targets the leukemia-initiating cells in a Tal1/Lmo2 mouse model of T-ALL.
    Tatarek J; Cullion K; Ashworth T; Gerstein R; Aster JC; Kelliher MA
    Blood; 2011 Aug; 118(6):1579-90. PubMed ID: 21670468
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma.
    Tan Q; Brunetti L; Rousseaux MWC; Lu HC; Wan YW; Revelli JP; Liu Z; Goodell MA; Zoghbi HY
    Proc Natl Acad Sci U S A; 2018 Feb; 115(7):E1511-E1519. PubMed ID: 29382756
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.