BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

516 related articles for article (PubMed ID: 20937815)

  • 1. Rapamycin inhibits cytoskeleton reorganization and cell motility by suppressing RhoA expression and activity.
    Liu L; Luo Y; Chen L; Shen T; Xu B; Chen W; Zhou H; Han X; Huang S
    J Biol Chem; 2010 Dec; 285(49):38362-73. PubMed ID: 20937815
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rapamycin inhibits cell motility by suppression of mTOR-mediated S6K1 and 4E-BP1 pathways.
    Liu L; Li F; Cardelli JA; Martin KA; Blenis J; Huang S
    Oncogene; 2006 Nov; 25(53):7029-40. PubMed ID: 16715128
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rapamycin attenuates BAFF-extended proliferation and survival via disruption of mTORC1/2 signaling in normal and neoplastic B-lymphoid cells.
    Zeng Q; Qin S; Zhang H; Liu B; Qin J; Wang X; Zhang R; Liu C; Dong X; Zhang S; Huang S; Chen L
    J Cell Physiol; 2018 Jan; 233(1):516-529. PubMed ID: 28300280
    [TBL] [Abstract][Full Text] [Related]  

  • 4. RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells.
    Gordon BS; Kazi AA; Coleman CS; Dennis MD; Chau V; Jefferson LS; Kimball SR
    Cell Signal; 2014 Mar; 26(3):461-7. PubMed ID: 24316235
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion.
    Chen L; Xu B; Liu L; Liu C; Luo Y; Chen X; Barzegar M; Chung J; Huang S
    Oncotarget; 2015 Mar; 6(9):7136-50. PubMed ID: 25762619
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rapamycin inhibits F-actin reorganization and phosphorylation of focal adhesion proteins.
    Liu L; Chen L; Chung J; Huang S
    Oncogene; 2008 Aug; 27(37):4998-5010. PubMed ID: 18504440
    [TBL] [Abstract][Full Text] [Related]  

  • 7. mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways.
    Gulhati P; Bowen KA; Liu J; Stevens PD; Rychahou PG; Chen M; Lee EY; Weiss HL; O'Connor KL; Gao T; Evers BM
    Cancer Res; 2011 May; 71(9):3246-56. PubMed ID: 21430067
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling.
    Woo SY; Kim DH; Jun CB; Kim YM; Haar EV; Lee SI; Hegg JW; Bandhakavi S; Griffin TJ; Kim DH
    J Biol Chem; 2007 Aug; 282(35):25604-12. PubMed ID: 17599906
    [TBL] [Abstract][Full Text] [Related]  

  • 9. mTOR is required for asymmetric division through small GTPases in mouse oocytes.
    Lee SE; Sun SC; Choi HY; Uhm SJ; Kim NH
    Mol Reprod Dev; 2012 May; 79(5):356-66. PubMed ID: 22407942
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility.
    Gulati N; Karsy M; Albert L; Murali R; Jhanwar-Uniyal M
    Int J Oncol; 2009 Oct; 35(4):731-40. PubMed ID: 19724909
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The proline-rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1.
    Oshiro N; Takahashi R; Yoshino K; Tanimura K; Nakashima A; Eguchi S; Miyamoto T; Hara K; Takehana K; Avruch J; Kikkawa U; Yonezawa K
    J Biol Chem; 2007 Jul; 282(28):20329-39. PubMed ID: 17517883
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Site-specific mTOR phosphorylation promotes mTORC1-mediated signaling and cell growth.
    Acosta-Jaquez HA; Keller JA; Foster KG; Ekim B; Soliman GA; Feener EP; Ballif BA; Fingar DC
    Mol Cell Biol; 2009 Aug; 29(15):4308-24. PubMed ID: 19487463
    [TBL] [Abstract][Full Text] [Related]  

  • 13. RhoE inhibits 4E-BP1 phosphorylation and eIF4E function impairing cap-dependent translation.
    Villalonga P; Fernández de Mattos S; Ridley AJ
    J Biol Chem; 2009 Dec; 284(51):35287-96. PubMed ID: 19850923
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CD40-induced signaling in human endothelial cells results in mTORC2- and Akt-dependent expression of vascular endothelial growth factor in vitro and in vivo.
    Dormond O; Contreras AG; Meijer E; Datta D; Flynn E; Pal S; Briscoe DM
    J Immunol; 2008 Dec; 181(11):8088-95. PubMed ID: 19018001
    [TBL] [Abstract][Full Text] [Related]  

  • 15. An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1.
    Thoreen CC; Kang SA; Chang JW; Liu Q; Zhang J; Gao Y; Reichling LJ; Sim T; Sabatini DM; Gray NS
    J Biol Chem; 2009 Mar; 284(12):8023-32. PubMed ID: 19150980
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hydrogen peroxide impairs insulin-stimulated assembly of mTORC1.
    Zhang L; Kimball SR; Jefferson LS; Shenberger JS
    Free Radic Biol Med; 2009 Jun; 46(11):1500-9. PubMed ID: 19281842
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rapamycin inhibits mSin1 phosphorylation independently of mTORC1 and mTORC2.
    Luo Y; Liu L; Wu Y; Singh K; Su B; Zhang N; Liu X; Shen Y; Huang S
    Oncotarget; 2015 Feb; 6(6):4286-98. PubMed ID: 25738366
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Relieving autophagy and 4EBP1 from rapamycin resistance.
    Nyfeler B; Bergman P; Triantafellow E; Wilson CJ; Zhu Y; Radetich B; Finan PM; Klionsky DJ; Murphy LO
    Mol Cell Biol; 2011 Jul; 31(14):2867-76. PubMed ID: 21576371
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rapamycin prevents cadmium-induced neuronal cell death via targeting both mTORC1 and mTORC2 pathways.
    Xu C; Liu C; Liu L; Zhang R; Zhang H; Chen S; Luo Y; Chen L; Huang S
    Neuropharmacology; 2015 Oct; 97():35-45. PubMed ID: 26002629
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PRAS40 is a target for mammalian target of rapamycin complex 1 and is required for signaling downstream of this complex.
    Fonseca BD; Smith EM; Lee VH; MacKintosh C; Proud CG
    J Biol Chem; 2007 Aug; 282(34):24514-24. PubMed ID: 17604271
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.