BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 20941725)

  • 1. Development of an activity-based probe for autotaxin.
    Cavalli S; Houben AJ; Albers HM; van Tilburg EW; de Ru A; Aoki J; van Veelen P; Moolenaar WH; Ovaa H
    Chembiochem; 2010 Nov; 11(16):2311-7. PubMed ID: 20941725
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of non-lipid autotaxin inhibitors.
    Hoeglund AB; Howard AL; Wanjala IW; Pham TC; Parrill AL; Baker DL
    Bioorg Med Chem; 2010 Jan; 18(2):769-76. PubMed ID: 20005724
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Discovery and optimization of boronic acid based inhibitors of autotaxin.
    Albers HM; van Meeteren LA; Egan DA; van Tilburg EW; Moolenaar WH; Ovaa H
    J Med Chem; 2010 Jul; 53(13):4958-67. PubMed ID: 20536182
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pharmacophore development and application toward the identification of novel, small-molecule autotaxin inhibitors.
    North EJ; Howard AL; Wanjala IW; Pham TC; Baker DL; Parrill AL
    J Med Chem; 2010 Apr; 53(8):3095-105. PubMed ID: 20349977
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Kinetic analysis of autotaxin reveals substrate-specific catalytic pathways and a mechanism for lysophosphatidic acid distribution.
    Saunders LP; Cao W; Chang WC; Albright RA; Braddock DT; De La Cruz EM
    J Biol Chem; 2011 Aug; 286(34):30130-41. PubMed ID: 21719699
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development.
    van Meeteren LA; Ruurs P; Stortelers C; Bouwman P; van Rooijen MA; Pradère JP; Pettit TR; Wakelam MJ; Saulnier-Blache JS; Mummery CL; Moolenaar WH; Jonkers J
    Mol Cell Biol; 2006 Jul; 26(13):5015-22. PubMed ID: 16782887
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional invalidation of the autotaxin gene by a single amino acid mutation in mouse is lethal.
    Ferry G; Giganti A; Cogé F; Bertaux F; Thiam K; Boutin JA
    FEBS Lett; 2007 Jul; 581(18):3572-8. PubMed ID: 17628547
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Fluorogenic phospholipid substrate to detect lysophospholipase D/autotaxin activity.
    Ferguson CG; Bigman CS; Richardson RD; van Meeteren LA; Moolenaar WH; Prestwich GD
    Org Lett; 2006 May; 8(10):2023-6. PubMed ID: 16671772
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Benzyl and naphthalene methylphosphonic acid inhibitors of autotaxin with anti-invasive and anti-metastatic activity.
    Gupte R; Patil R; Liu J; Wang Y; Lee SC; Fujiwara Y; Fells J; Bolen AL; Emmons-Thompson K; Yates CR; Siddam A; Panupinthu N; Pham TC; Baker DL; Parrill AL; Mills GB; Tigyi G; Miller DD
    ChemMedChem; 2011 May; 6(5):922-35. PubMed ID: 21465666
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation and biological activities of the autotaxin-LPA axis.
    van Meeteren LA; Moolenaar WH
    Prog Lipid Res; 2007 Mar; 46(2):145-60. PubMed ID: 17459484
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Lysophosphatidylmethanol is a pan lysophosphatidic acid receptor agonist and is produced by autotaxin in blood.
    Endo T; Kano K; Motoki R; Hama K; Okudaira S; Ishida M; Ogiso H; Tanaka M; Matsuki N; Taguchi R; Kanai M; Shibasaki M; Arai H; Aoki J
    J Biochem; 2009 Aug; 146(2):283-93. PubMed ID: 19416959
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mammary tumorigenesis through LPA receptor signaling.
    Jonkers J; Moolenaar WH
    Cancer Cell; 2009 Jun; 15(6):457-9. PubMed ID: 19477423
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel point mutations attenuate autotaxin activity.
    Koh E; Bandle RW; Roberts DD; Stracke ML; Clair T
    Lipids Health Dis; 2009 Feb; 8():4. PubMed ID: 19222837
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of phosphonate derivatives as autotaxin (ATX) inhibitors.
    Cui P; Tomsig JL; McCalmont WF; Lee S; Becker CJ; Lynch KR; Macdonald TL
    Bioorg Med Chem Lett; 2007 Mar; 17(6):1634-40. PubMed ID: 17257836
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and structure-activity relationships of tyrosine-based inhibitors of autotaxin (ATX).
    East JE; Kennedy AJ; Tomsig JL; De Leon AR; Lynch KR; Macdonald TL
    Bioorg Med Chem Lett; 2010 Dec; 20(23):7132-6. PubMed ID: 20951039
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Autotaxin is induced by TSA through HDAC3 and HDAC7 inhibition and antagonizes the TSA-induced cell apoptosis.
    Li S; Wang B; Xu Y; Zhang J
    Mol Cancer; 2011 Feb; 10():18. PubMed ID: 21314984
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Autotaxin promotes cancer invasion via the lysophosphatidic acid receptor 4: participation of the cyclic AMP/EPAC/Rac1 signaling pathway in invadopodia formation.
    Harper K; Arsenault D; Boulay-Jean S; Lauzier A; Lucien F; Dubois CM
    Cancer Res; 2010 Jun; 70(11):4634-43. PubMed ID: 20484039
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Scalable purification and characterization of the extracellular domain of human autotaxin from prokaryotic cells.
    Haga A; Hashimoto K; Tanaka N; Nakamura KT; Deyashiki Y
    Protein Expr Purif; 2008 May; 59(1):9-17. PubMed ID: 18249559
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate.
    van Meeteren LA; Ruurs P; Christodoulou E; Goding JW; Takakusa H; Kikuchi K; Perrakis A; Nagano T; Moolenaar WH
    J Biol Chem; 2005 Jun; 280(22):21155-61. PubMed ID: 15769751
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Anticancer activity of FTY720: phosphorylated FTY720 inhibits autotaxin, a metastasis-enhancing and angiogenic lysophospholipase D.
    van Meeteren LA; Brinkmann V; Saulnier-Blache JS; Lynch KR; Moolenaar WH
    Cancer Lett; 2008 Aug; 266(2):203-8. PubMed ID: 18378389
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.