These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

205 related articles for article (PubMed ID: 20945503)

  • 1. Unveiling the methylation status of CpG dinucleotides in the substituted segment of the human p53 knock-in (Hupki) mouse genome.
    Kim SI; Hollstein M; Pfeifer GP; Besaratinia A
    Mol Carcinog; 2010 Dec; 49(12):999-1006. PubMed ID: 20945503
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Applications of the human p53 knock-in (Hupki) mouse model for human carcinogen testing.
    Besaratinia A; Pfeifer GP
    FASEB J; 2010 Aug; 24(8):2612-9. PubMed ID: 20371617
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Linking environmental carcinogen exposure to TP53 mutations in human tumours using the human TP53 knock-in (Hupki) mouse model.
    Kucab JE; Phillips DH; Arlt VM
    FEBS J; 2010 Jun; 277(12):2567-83. PubMed ID: 20553493
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Methylated CpG dinucleotides are the preferential targets for G-to-T transversion mutations induced by benzo[a]pyrene diol epoxide in mammalian cells: similarities with the p53 mutation spectrum in smoking-associated lung cancers.
    Yoon JH; Smith LE; Feng Z; Tang M; Lee CS; Pfeifer GP
    Cancer Res; 2001 Oct; 61(19):7110-7. PubMed ID: 11585742
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Knock-in mice with a chimeric human/murine p53 gene develop normally and show wild-type p53 responses to DNA damaging agents: a new biomedical research tool.
    Luo JL; Yang Q; Tong WM; Hergenhahn M; Wang ZQ; Hollstein M
    Oncogene; 2001 Jan; 20(3):320-8. PubMed ID: 11313961
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Damage-inducible intragenic demethylation of the human TP53 tumor suppressor gene is associated with transcription from an alternative intronic promoter.
    Blackburn J; Roden DL; Ng R; Wu J; Bosman A; Epstein RJ
    Mol Carcinog; 2016 Dec; 55(12):1940-1951. PubMed ID: 26676339
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human tumor p53 mutations are selected for in mouse embryonic fibroblasts harboring a humanized p53 gene.
    Liu Z; Hergenhahn M; Schmeiser HH; Wogan GN; Hong A; Hollstein M
    Proc Natl Acad Sci U S A; 2004 Mar; 101(9):2963-8. PubMed ID: 14976251
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Complete and tissue-independent methylation of CpG sites in the p53 gene: implications for mutations in human cancers.
    Tornaletti S; Pfeifer GP
    Oncogene; 1995 Apr; 10(8):1493-9. PubMed ID: 7731703
    [TBL] [Abstract][Full Text] [Related]  

  • 9. UV-induced DNA damage and mutations in Hupki (human p53 knock-in) mice recapitulate p53 hotspot alterations in sun-exposed human skin.
    Luo JL; Tong WM; Yoon JH; Hergenhahn M; Koomagi R; Yang Q; Galendo D; Pfeifer GP; Wang ZQ; Hollstein M
    Cancer Res; 2001 Nov; 61(22):8158-63. PubMed ID: 11719445
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cytosine methylation determines hot spots of DNA damage in the human P53 gene.
    Denissenko MF; Chen JX; Tang MS; Pfeifer GP
    Proc Natl Acad Sci U S A; 1997 Apr; 94(8):3893-8. PubMed ID: 9108075
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Non-CpG cytosine methylation of p53 exon 5 in non-small cell lung carcinoma.
    Kouidou S; Agidou T; Kyrkou A; Andreou A; Katopodi T; Georgiou E; Krikelis D; Dimitriadou A; Spanos P; Tsilikas C; Destouni H; Tzimagiorgis G
    Lung Cancer; 2005 Dec; 50(3):299-307. PubMed ID: 16125822
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutagenicity of acrylamide and glycidamide in human TP53 knock-in (Hupki) mouse embryo fibroblasts.
    Hölzl-Armstrong L; Kucab JE; Moody S; Zwart EP; Loutkotová L; Duffy V; Luijten M; Gamboa da Costa G; Stratton MR; Phillips DH; Arlt VM
    Arch Toxicol; 2020 Dec; 94(12):4173-4196. PubMed ID: 32886187
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Methylation of CpG dinucleotides in the lacI gene of the Big Blue transgenic mouse.
    You YH; Halangoda A; Buettner V; Hill K; Sommer S; Pfeifer G
    Mutat Res; 1998 Dec; 420(1-3):55-65. PubMed ID: 9838042
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Monitoring methylation changes in cancer.
    Beier V; Mund C; Hoheisel JD
    Adv Biochem Eng Biotechnol; 2007; 104():1-11. PubMed ID: 17290816
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Aflatoxin-B exposure does not lead to p53 mutations but results in enhanced liver cancer of Hupki (human p53 knock-in) mice.
    Tong WM; Lee MK; Galendo D; Wang ZQ; Sabapathy K
    Int J Cancer; 2006 Aug; 119(4):745-9. PubMed ID: 16557586
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of CpG methylation on recognition of DNA by the tumour suppressor p53.
    Petrovich M; Veprintsev DB
    J Mol Biol; 2009 Feb; 386(1):72-80. PubMed ID: 19084536
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutational spectra of human cancer.
    Pfeifer GP; Besaratinia A
    Hum Genet; 2009 Jun; 125(5-6):493-506. PubMed ID: 19308457
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Symmetric and asymmetric DNA methylation in the human IGF2-H19 imprinted region.
    Vu TH; Li T; Nguyen D; Nguyen BT; Yao XM; Hu JF; Hoffman AR
    Genomics; 2000 Mar; 64(2):132-43. PubMed ID: 10729220
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Resolution of the DNA methylation state of single CpG dyads using in silico strand annealing and WGBS data.
    Xu C; Corces VG
    Nat Protoc; 2019 Jan; 14(1):202-216. PubMed ID: 30542058
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evidence for non-CpG methylation in mammals.
    Yan J; Zierath JR; Barrès R
    Exp Cell Res; 2011 Nov; 317(18):2555-61. PubMed ID: 21925168
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.