BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 20947411)

  • 1. Apoptosis assays for quantifying the bioactivity of anticancer drug products.
    Brunelle JK; Zhang B
    Drug Resist Updat; 2010 Dec; 13(6):172-9. PubMed ID: 20947411
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Benzethonium chloride: a novel anticancer agent identified by using a cell-based small-molecule screen.
    Yip KW; Mao X; Au PY; Hedley DW; Chow S; Dalili S; Mocanu JD; Bastianutto C; Schimmer A; Liu FF
    Clin Cancer Res; 2006 Sep; 12(18):5557-69. PubMed ID: 17000693
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evaluation of cell proliferation and cell death based assays in chemosensitivity testing.
    Gerçel-Taylor C; Ackermann MA; Taylor DD
    Anticancer Res; 2001; 21(4A):2761-8. PubMed ID: 11724352
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Rapid fluorescence-based reporter-gene assays to evaluate the cytotoxicity and antitumor drug potential of platinum complexes.
    Sandman KE; Marla SS; Zlokarnik G; Lippard SJ
    Chem Biol; 1999 Aug; 6(8):541-51. PubMed ID: 10421759
    [TBL] [Abstract][Full Text] [Related]  

  • 5. High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth.
    Iljin K; Ketola K; Vainio P; Halonen P; Kohonen P; Fey V; Grafström RC; Perälä M; Kallioniemi O
    Clin Cancer Res; 2009 Oct; 15(19):6070-8. PubMed ID: 19789329
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Apoptosis: mediator or mode of cell killing by anticancer agents?
    Brown JM; Wouters BG
    Drug Resist Updat; 2001 Apr; 4(2):135-6. PubMed ID: 11512523
    [No Abstract]   [Full Text] [Related]  

  • 7. A polymer microstructure array for the formation, culturing, and high throughput drug screening of breast cancer spheroids.
    Markovitz-Bishitz Y; Tauber Y; Afrimzon E; Zurgil N; Sobolev M; Shafran Y; Deutsch A; Howitz S; Deutsch M
    Biomaterials; 2010 Nov; 31(32):8436-44. PubMed ID: 20692698
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of substituted N-phenyl nicotinamides as potent inducers of apoptosis using a cell- and caspase-based high throughput screening assay.
    Cai SX; Nguyen B; Jia S; Herich J; Guastella J; Reddy S; Tseng B; Drewe J; Kasibhatla S
    J Med Chem; 2003 Jun; 46(12):2474-81. PubMed ID: 12773051
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 1. Structure-activity relationships of the 4-aryl group.
    Kemnitzer W; Drewe J; Jiang S; Zhang H; Wang Y; Zhao J; Jia S; Herich J; Labreque D; Storer R; Meerovitch K; Bouffard D; Rej R; Denis R; Blais C; Lamothe S; Attardo G; Gourdeau H; Tseng B; Kasibhatla S; Cai SX
    J Med Chem; 2004 Dec; 47(25):6299-310. PubMed ID: 15566300
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2: Structure-activity relationships of the 4-, 5-, 6-, 7- and 8-positions.
    Kemnitzer W; Kuemmerle J; Jiang S; Sirisoma N; Kasibhatla S; Crogan-Grundy C; Tseng B; Drewe J; Cai SX
    Bioorg Med Chem Lett; 2009 Jul; 19(13):3481-4. PubMed ID: 19467598
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Screening for compounds that induce apoptosis of cancer cells grown as multicellular spheroids.
    Herrmann R; Fayad W; Schwarz S; Berndtsson M; Linder S
    J Biomol Screen; 2008 Jan; 13(1):1-8. PubMed ID: 18040052
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Problems in the design of anticancer agents.
    D'Incalci M; Balconi G; Broggini M; Colombo T; Marzola M; Morali F; Pang Y; Sen S; Spinelli L
    Cancer Surv; 1989; 8(3):535-55. PubMed ID: 2701084
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Screening of natural products for therapeutic activity against solid tumors.
    El-Menshawi BS; Fayad W; Mahmoud K; El-Hallouty SM; El-Manawaty M; Olofsson MH; Linder S
    Indian J Exp Biol; 2010 Mar; 48(3):258-64. PubMed ID: 21046978
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanisms of induction of apoptosis by anthraquinone anticancer drugs aclarubicin and mitoxantrone in comparison with doxorubicin: relation to drug cytotoxicity and caspase-3 activation.
    Koceva-Chyła A; Jedrzejczak M; Skierski J; Kania K; Jóźwiak Z
    Apoptosis; 2005 Dec; 10(6):1497-514. PubMed ID: 16215684
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database.
    Nikolovska-Coleska Z; Xu L; Hu Z; Tomita Y; Li P; Roller PP; Wang R; Fang X; Guo R; Zhang M; Lippman ME; Yang D; Wang S
    J Med Chem; 2004 May; 47(10):2430-40. PubMed ID: 15115387
    [TBL] [Abstract][Full Text] [Related]  

  • 16. High-throughput screening of natural products for cancer therapy.
    Harvey AL; Cree IA
    Planta Med; 2010 Aug; 76(11):1080-6. PubMed ID: 20635309
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evaluation of indenoisoquinoline topoisomerase I inhibitors using a hollow fiber assay.
    Morrell A; Jayaraman M; Nagarajan M; Fox BM; Meckley MR; Ioanoviciu A; Pommier Y; Antony S; Hollingshead M; Cushman M
    Bioorg Med Chem Lett; 2006 Aug; 16(16):4395-9. PubMed ID: 16750365
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis of 4β-N-polyaromatic substituted podophyllotoxins: DNA topoisomerase inhibition, anticancer and apoptosis-inducing activities.
    Kamal A; Kumar BA; Suresh P; Agrawal SK; Chashoo G; Singh SK; Saxena AK
    Bioorg Med Chem; 2010 Dec; 18(24):8493-500. PubMed ID: 21074444
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The contemporary drug development process: advances and challenges in preclinical and clinical development.
    Garrett MD; Walton MI; McDonald E; Judson I; Workman P
    Prog Cell Cycle Res; 2003; 5():145-58. PubMed ID: 14593708
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of substituted 4-anilino-2-(2-pyridyl)pyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. Part 1: structure-activity relationships of the 4-anilino group.
    Sirisoma N; Kasibhatla S; Nguyen B; Pervin A; Wang Y; Claassen G; Tseng B; Drewe J; Cai SX
    Bioorg Med Chem; 2006 Dec; 14(23):7761-73. PubMed ID: 16919962
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.