These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

121 related articles for article (PubMed ID: 20954731)

  • 1. Properties and synthesis of 2-{2-fluoro (or bromo)-4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid: nonsteroidal anti-inflammatory drugs with low membrane permeabilizing and gastric lesion-producing activities.
    Yamakawa N; Suemasu S; Matoyama M; Kimoto A; Takeda M; Tanaka K; Ishihara T; Katsu T; Okamoto Y; Otsuka M; Mizushima T
    J Med Chem; 2010 Nov; 53(21):7879-82. PubMed ID: 20954731
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and biological evaluation of loxoprofen derivatives.
    Yamakawa N; Suemasu S; Matoyama M; Tanaka K; Katsu T; Miyata K; Okamoto Y; Otsuka M; Mizushima T
    Bioorg Med Chem; 2011 Jun; 19(11):3299-311. PubMed ID: 21570308
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and biological evaluation of derivatives of 2-{2-fluoro-4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid: nonsteroidal anti-inflammatory drugs with low gastric ulcerogenic activity.
    Yamakawa N; Suemasu S; Okamoto Y; Tanaka K; Ishihara T; Asano T; Miyata K; Otsuka M; Mizushima T
    J Med Chem; 2012 Jun; 55(11):5143-50. PubMed ID: 22404396
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel nonsteroidal antiinflammatory drugs possessing a nitric oxide donor diazen-1-ium-1,2-diolate moiety: design, synthesis, biological evaluation, and nitric oxide release studies.
    Velázquez C; Praveen Rao PN; Knaus EE
    J Med Chem; 2005 Jun; 48(12):4061-7. PubMed ID: 15943479
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ethanesulfohydroxamic acid ester prodrugs of nonsteroidal anti-inflammatory drugs (NSAIDs): synthesis, nitric oxide and nitroxyl release, cyclooxygenase inhibition, anti-inflammatory, and ulcerogenicity index studies.
    Huang Z; Velázquez CA; Abdellatif KR; Chowdhury MA; Reisz JA; DuMond JF; King SB; Knaus EE
    J Med Chem; 2011 Mar; 54(5):1356-64. PubMed ID: 21280601
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gastrointestinal mucosal injury following repeated daily oral administration of conventional formulations of indometacin and other non-steroidal anti-inflammatory drugs to pigs: a model for human gastrointestinal disease.
    Rainsford KD; Stetsko PI; Sirko SP; Debski S
    J Pharm Pharmacol; 2003 May; 55(5):661-8. PubMed ID: 12831509
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 1. Thiazolone and oxazolone series.
    Song Y; Connor DT; Doubleday R; Sorenson RJ; Sercel AD; Unangst PC; Roth BD; Gilbertsen RB; Chan K; Schrier DJ; Guglietta A; Bornemeier DA; Dyer RD
    J Med Chem; 1999 Apr; 42(7):1151-60. PubMed ID: 10197959
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-activity relationship of celecoxib and rofecoxib for the membrane permeabilizing activity.
    Yamakawa N; Suzuki K; Yamashita Y; Katsu T; Hanaya K; Shoji M; Sugai T; Mizushima T
    Bioorg Med Chem; 2014 Apr; 22(8):2529-34. PubMed ID: 24650702
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chlorzoxazone esters of some non-steroidal anti-inflammatory (NSAI) carboxylic acids as mutual prodrugs: design, synthesis, pharmacological investigations and docking studies.
    Abdel-Azeem AZ; Abdel-Hafez AA; El-Karamany GS; Farag HH
    Bioorg Med Chem; 2009 May; 17(10):3665-70. PubMed ID: 19398345
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Co-administration of water containing magnesium ion prevents loxoprofen-induced lesions in gastric mucosa of adjuvant-induced arthritis rat.
    Nagai N; Takeda A; Itanami Y; Ito Y
    Biol Pharm Bull; 2012; 35(12):2230-7. PubMed ID: 23207775
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of direct cytotoxic effects of NSAIDs in the induction of gastric lesions.
    Tomisato W; Tsutsumi S; Hoshino T; Hwang HJ; Mio M; Tsuchiya T; Mizushima T
    Biochem Pharmacol; 2004 Feb; 67(3):575-85. PubMed ID: 15037209
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Membrane permeabilization by non-steroidal anti-inflammatory drugs.
    Tomisato W; Tanaka K; Katsu T; Kakuta H; Sasaki K; Tsutsumi S; Hoshino T; Aburaya M; Li D; Tsuchiya T; Suzuki K; Yokomizo K; Mizushima T
    Biochem Biophys Res Commun; 2004 Oct; 323(3):1032-9. PubMed ID: 15381103
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ulcerogenicity and effect on inhibition of prostaglandin generation of indometacin farnesil, a prodrug of indomethacin, in rat gastric mucosa: comparison with indomethacin or loxoprofen.
    Arakawa T; Fukuda T; Nakagawa K; Higuchi K; Watanabe T; Tominaga K; Kobayashi K
    Drugs Exp Clin Res; 1995; 21(3):85-8. PubMed ID: 7555616
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Lafutidine prevents low-dose aspirin and loxoprofen induced gastric injury: a randomized, double-blinded, placebo controlled study.
    Kato M; Kamada G; Yamamoto K; Nishida U; Imai A; Yoshida T; Ono S; Nakagawa M; Nakagawa S; Shimizu Y; Asaka M
    J Gastroenterol Hepatol; 2010 Oct; 25(10):1631-5. PubMed ID: 20880171
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [Gastropathy caused by nonsteroidal anti-inflammatory agents].
    Márquez-Murillo MF; Suazo J; Poo JL
    Rev Invest Clin; 1997; 49(3):241-54. PubMed ID: 9380979
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NSAIDs, coxibs, CINOD and H2S-releasing NSAIDs: what lies beyond the horizon.
    Fiorucci S; Santucci L; Distrutti E
    Dig Liver Dis; 2007 Dec; 39(12):1043-51. PubMed ID: 17997373
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NSAID-induced gastric mucosal damage.
    Semble EL; Wu WC
    Am Fam Physician; 1987 Jun; 35(6):101-8. PubMed ID: 3332745
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of a unique nsaid, fluoro-loxoprofen with gastroprotective activity.
    Suemasu S; Yamakawa N; Ishihara T; Asano T; Tahara K; Tanaka K; Matsui H; Okamoto Y; Otsuka M; Takeuchi K; Suzuki H; Mizushima T
    Biochem Pharmacol; 2012 Dec; 84(11):1470-81. PubMed ID: 23022227
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Low direct cytotoxicity of loxoprofen on gastric mucosal cells.
    Yamakawa N; Suemasu S; Kimoto A; Arai Y; Ishihara T; Yokomizo K; Okamoto Y; Otsuka M; Tanaka K; Mizushima T
    Biol Pharm Bull; 2010; 33(3):398-403. PubMed ID: 20190399
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 2. 1,3,4- and 1,2,4-thiadiazole series.
    Song Y; Connor DT; Sercel AD; Sorenson RJ; Doubleday R; Unangst PC; Roth BD; Beylin VG; Gilbertsen RB; Chan K; Schrier DJ; Guglietta A; Bornemeier DA; Dyer RD
    J Med Chem; 1999 Apr; 42(7):1161-9. PubMed ID: 10197960
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.