BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

197 related articles for article (PubMed ID: 20958979)

  • 1. Evaluation of the endoplasmic reticulum-stress response in eIF2B-mutated lymphocytes and lymphoblasts from CACH/VWM patients.
    Horzinski L; Kantor L; Huyghe A; Schiffmann R; Elroy-Stein O; Boespflug-Tanguy O; Fogli A
    BMC Neurol; 2010 Oct; 10():94. PubMed ID: 20958979
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Heightened stress response in primary fibroblasts expressing mutant eIF2B genes from CACH/VWM leukodystrophy patients.
    Kantor L; Harding HP; Ron D; Schiffmann R; Kaneski CR; Kimball SR; Elroy-Stein O
    Hum Genet; 2005 Oct; 118(1):99-106. PubMed ID: 16041584
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A point mutation in translation initiation factor 2B leads to a continuous hyper stress state in oligodendroglial-derived cells.
    Kantor L; Pinchasi D; Mintz M; Hathout Y; Vanderver A; Elroy-Stein O
    PLoS One; 2008; 3(11):e3783. PubMed ID: 19023445
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Eukaryotic initiation factor 2B (eIF2B) GEF activity as a diagnostic tool for EIF2B-related disorders.
    Horzinski L; Huyghe A; Cardoso MC; Gonthier C; Ouchchane L; Schiffmann R; Blanc P; Boespflug-Tanguy O; Fogli A
    PLoS One; 2009 Dec; 4(12):e8318. PubMed ID: 20016818
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A yeast purification system for human translation initiation factors eIF2 and eIF2Bε and their use in the diagnosis of CACH/VWM disease.
    de Almeida RA; Fogli A; Gaillard M; Scheper GC; Boesflug-Tanguy O; Pavitt GD
    PLoS One; 2013; 8(1):e53958. PubMed ID: 23335982
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Vanishing white matter: deregulated integrated stress response as therapy target.
    Abbink TEM; Wisse LE; Jaku E; Thiecke MJ; Voltolini-González D; Fritsen H; Bobeldijk S; Ter Braak TJ; Polder E; Postma NL; Bugiani M; Struijs EA; Verheijen M; Straat N; van der Sluis S; Thomas AAM; Molenaar D; van der Knaap MS
    Ann Clin Transl Neurol; 2019 Aug; 6(8):1407-1422. PubMed ID: 31402619
    [TBL] [Abstract][Full Text] [Related]  

  • 7. [Eukaryotic translation initiation factor 2B and leukoencephalopathy with vanishing white matter].
    Pan YX; Wu Y; Niu ZP; Jiang YW
    Beijing Da Xue Xue Bao Yi Xue Ban; 2009 Oct; 41(5):608-10. PubMed ID: 19829687
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Toll-like receptor activation suppresses ER stress factor CHOP and translation inhibition through activation of eIF2B.
    Woo CW; Kutzler L; Kimball SR; Tabas I
    Nat Cell Biol; 2012 Jan; 14(2):192-200. PubMed ID: 22231169
    [TBL] [Abstract][Full Text] [Related]  

  • 9. eIF2B: recent structural and functional insights into a key regulator of translation.
    Wortham NC; Proud CG
    Biochem Soc Trans; 2015 Dec; 43(6):1234-40. PubMed ID: 26614666
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Decreased guanine nucleotide exchange factor activity in eIF2B-mutated patients.
    Fogli A; Schiffmann R; Hugendubler L; Combes P; Bertini E; Rodriguez D; Kimball SR; Boespflug-Tanguy O
    Eur J Hum Genet; 2004 Jul; 12(7):561-6. PubMed ID: 15054402
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Energy Status of Astrocytes Is the Achilles' Heel of eIF2B-Leukodystrophy.
    Herrero M; Daw M; Atzmon A; Elroy-Stein O
    Cells; 2021 Jul; 10(8):. PubMed ID: 34440627
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Different Eukaryotic Initiation Factor 2Bε Mutations Lead to Various Degrees of Intolerance to the Stress of Endoplasmic Reticulum in Oligodendrocytes.
    Chen N; Jiang YW; Hao HJ; Ban TT; Gao K; Zhang ZB; Wang JM; Wu Y
    Chin Med J (Engl); 2015 Jul; 128(13):1772-7. PubMed ID: 26112719
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA.
    Galehdar Z; Swan P; Fuerth B; Callaghan SM; Park DS; Cregan SP
    J Neurosci; 2010 Dec; 30(50):16938-48. PubMed ID: 21159964
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of fatty acid synthase induces endoplasmic reticulum stress in tumor cells.
    Little JL; Wheeler FB; Fels DR; Koumenis C; Kridel SJ
    Cancer Res; 2007 Feb; 67(3):1262-9. PubMed ID: 17283163
    [TBL] [Abstract][Full Text] [Related]  

  • 15.
    Moon SL; Parker R
    RNA; 2018 Jun; 24(6):841-852. PubMed ID: 29632131
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Poor cerebral inflammatory response in eIF2B knock-in mice: implications for the aetiology of vanishing white matter disease.
    Cabilly Y; Barbi M; Geva M; Marom L; Chetrit D; Ehrlich M; Elroy-Stein O
    PLoS One; 2012; 7(10):e46715. PubMed ID: 23056417
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Paradoxical Sensitivity to an Integrated Stress Response Blocking Mutation in Vanishing White Matter Cells.
    Sekine Y; Zyryanova A; Crespillo-Casado A; Amin-Wetzel N; Harding HP; Ron D
    PLoS One; 2016; 11(11):e0166278. PubMed ID: 27812215
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Endoplasmic reticulum stress intolerance in EIF2B3 mutant oligodendrocytes is modulated by depressed autophagy.
    Chen N; Dai L; Jiang Y; Wang J; Hao H; Ren Y; Leng X; Zang L; Wu Y
    Brain Dev; 2016 May; 38(5):507-15. PubMed ID: 26625702
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cell death induced by the ER stressor thapsigargin involves death receptor 5, a non-autophagic function of MAP1LC3B, and distinct contributions from unfolded protein response components.
    Lindner P; Christensen SB; Nissen P; Møller JV; Engedal N
    Cell Commun Signal; 2020 Jan; 18(1):12. PubMed ID: 31987044
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Severity of vanishing white matter disease does not correlate with deficits in eIF2B activity or the integrity of eIF2B complexes.
    Liu R; van der Lei HD; Wang X; Wortham NC; Tang H; van Berkel CG; Mufunde TA; Huang W; van der Knaap MS; Scheper GC; Proud CG
    Hum Mutat; 2011 Sep; 32(9):1036-45. PubMed ID: 21560189
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.