BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

290 related articles for article (PubMed ID: 20959633)

  • 1. Zebrafish model of tuberous sclerosis complex reveals cell-autonomous and non-cell-autonomous functions of mutant tuberin.
    Kim SH; Speirs CK; Solnica-Krezel L; Ess KC
    Dis Model Mech; 2011 Mar; 4(2):255-67. PubMed ID: 20959633
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Localization of tuberous sclerosis 2 mRNA and its protein product tuberin in normal human brain and in cerebral lesions of patients with tuberous sclerosis.
    Kerfoot C; Wienecke R; Menchine M; Emelin J; Maize JC; Welsh CT; Norman MG; DeClue JE; Vinters HV
    Brain Pathol; 1996 Oct; 6(4):367-75. PubMed ID: 8944308
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb.
    Tee AR; Manning BD; Roux PP; Cantley LC; Blenis J
    Curr Biol; 2003 Aug; 13(15):1259-68. PubMed ID: 12906785
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tuberin and hamartin are aberrantly expressed and linked to clinical outcome in human breast cancer: the role of promoter methylation of TSC genes.
    Jiang WG; Sampson J; Martin TA; Lee-Jones L; Watkins G; Douglas-Jones A; Mokbel K; Mansel RE
    Eur J Cancer; 2005 Jul; 41(11):1628-36. PubMed ID: 15951164
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Heterozygous inactivation of tsc2 enhances tumorigenesis in p53 mutant zebrafish.
    Kim SH; Kowalski ML; Carson RP; Bridges LR; Ess KC
    Dis Model Mech; 2013 Jul; 6(4):925-33. PubMed ID: 23580196
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure of the Tuberous Sclerosis Complex 2 (TSC2) N Terminus Provides Insight into Complex Assembly and Tuberous Sclerosis Pathogenesis.
    Zech R; Kiontke S; Mueller U; Oeckinghaus A; Kümmel D
    J Biol Chem; 2016 Sep; 291(38):20008-20. PubMed ID: 27493206
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Loss of the tuberous sclerosis complex protein tuberin causes Purkinje cell degeneration.
    Reith RM; Way S; McKenna J; Haines K; Gambello MJ
    Neurobiol Dis; 2011 Jul; 43(1):113-22. PubMed ID: 21419848
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tuberous sclerosis as an underlying basis for infantile spasm.
    Yeung RS
    Int Rev Neurobiol; 2002; 49():315-32. PubMed ID: 12040899
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Evidence for separable functions of tuberous sclerosis gene products in mammalian cell cycle regulation.
    Miloloza A; Kubista M; Rosner M; Hengstschläger M
    J Neuropathol Exp Neurol; 2002 Feb; 61(2):154-63. PubMed ID: 11853018
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Establishment of human induced pluripotent stem cell lines, KMUGMCi006, from a patient with Tuberous sclerosis complex (TSC) bearing mosaic nonsense mutations in the Tuberous sclerosis complex 2 (TSC2) gene.
    Ura H; Togi S; Ozaki M; Hatanaka H; Niida Y
    Stem Cell Res; 2023 Aug; 70():103129. PubMed ID: 37271041
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Complex Neurological Phenotype in Mutant Mice Lacking Tsc2 in Excitatory Neurons of the Developing Forebrain(123).
    Crowell B; Lee GH; Nikolaeva I; Dal Pozzo V; D'Arcangelo G
    eNeuro; 2015; 2(6):. PubMed ID: 26693177
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tuberous sclerosis complex and DNA repair.
    Habib SL
    Adv Exp Med Biol; 2010; 685():84-94. PubMed ID: 20687497
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Heterozygosity for the tuberous sclerosis complex (TSC) gene products results in increased astrocyte numbers and decreased p27-Kip1 expression in TSC2+/- cells.
    Uhlmann EJ; Apicelli AJ; Baldwin RL; Burke SP; Bajenaru ML; Onda H; Kwiatkowski D; Gutmann DH
    Oncogene; 2002 Jun; 21(25):4050-9. PubMed ID: 12037687
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mourning Dr. Alfred G. Knudson: the two-hit hypothesis, tumor suppressor genes, and the tuberous sclerosis complex.
    Hino O; Kobayashi T
    Cancer Sci; 2017 Jan; 108(1):5-11. PubMed ID: 27862655
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tsc2 mutation rather than Tsc1 mutation dominantly causes a social deficit in a mouse model of tuberous sclerosis complex.
    Kashii H; Kasai S; Sato A; Hagino Y; Nishito Y; Kobayashi T; Hino O; Mizuguchi M; Ikeda K
    Hum Genomics; 2023 Feb; 17(1):4. PubMed ID: 36732866
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evidence for population variation in TSC1 and TSC2 gene expression.
    Jentarra GM; Rice SG; Olfers S; Saffen D; Narayanan V
    BMC Med Genet; 2011 Feb; 12():29. PubMed ID: 21345208
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tsc2 gene inactivation causes a more severe epilepsy phenotype than Tsc1 inactivation in a mouse model of tuberous sclerosis complex.
    Zeng LH; Rensing NR; Zhang B; Gutmann DH; Gambello MJ; Wong M
    Hum Mol Genet; 2011 Feb; 20(3):445-54. PubMed ID: 21062901
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Developmental expression of the tuberous sclerosis proteins tuberin and hamartin.
    Murthy V; Stemmer-Rachamimov AO; Haddad LA; Roy JE; Cutone AN; Beauchamp RL; Smith N; Louis DN; Ramesh V
    Acta Neuropathol; 2001 Mar; 101(3):202-10. PubMed ID: 11307618
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression of tuberin and hamartin in tuberous sclerosis complex-associated and sporadic cortical dysplasia of Taylor's balloon cell type.
    Grajkowska W; Kotulska K; Matyja E; Larysz-Brysz M; Mandera M; Roszkowski M; Domańska-Pakieła D; Lewik-Kowalik J; Jóźwiak S
    Folia Neuropathol; 2008; 46(1):43-8. PubMed ID: 18368626
    [TBL] [Abstract][Full Text] [Related]  

  • 20. mTOR-related neuropathology in mutant tsc2 zebrafish: Phenotypic, transcriptomic and pharmacological analysis.
    Scheldeman C; Mills JD; Siekierska A; Serra I; Copmans D; Iyer AM; Whalley BJ; Maes J; Jansen AC; Lagae L; Aronica E; de Witte PAM
    Neurobiol Dis; 2017 Dec; 108():225-237. PubMed ID: 28888969
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.