BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 20960027)

  • 1. Sensitivity of BRCA2 mutated human cell lines to Aurora kinase inhibition.
    Vidarsdottir L; Steingrimsdottir G; Bodvarsdottir SK; Ogmundsdottir HM; Eyfjord JE
    Invest New Drugs; 2012 Apr; 30(2):425-34. PubMed ID: 20960027
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of the aurora kinase inhibitors AZD1152-HQPA and ZM447439 on growth arrest and polyploidy in acute myeloid leukemia cell lines and primary blasts.
    Walsby E; Walsh V; Pepper C; Burnett A; Mills K
    Haematologica; 2008 May; 93(5):662-9. PubMed ID: 18367484
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ZM447439, the Aurora kinase B inhibitor, suppresses the growth of cervical cancer SiHa cells and enhances the chemosensitivity to cisplatin.
    Zhang L; Zhang S
    J Obstet Gynaecol Res; 2011 Jun; 37(6):591-600. PubMed ID: 21159048
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer.
    Gully CP; Zhang F; Chen J; Yeung JA; Velazquez-Torres G; Wang E; Yeung SC; Lee MH
    Mol Cancer; 2010 Feb; 9():42. PubMed ID: 20175926
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Determinants for the efficiency of anticancer drugs targeting either Aurora-A or Aurora-B kinases in human colon carcinoma cells.
    Kaestner P; Stolz A; Bastians H
    Mol Cancer Ther; 2009 Jul; 8(7):2046-56. PubMed ID: 19584233
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Aurora-A amplification associated with BRCA2 mutation in breast tumours.
    Bodvarsdottir SK; Hilmarsdottir H; Birgisdottir V; Steinarsdottir M; Jonasson JG; Eyfjord JE
    Cancer Lett; 2007 Apr; 248(1):96-102. PubMed ID: 16860930
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ZM447439, a novel promising aurora kinase inhibitor, provokes antiproliferative and proapoptotic effects alone and in combination with bio- and chemotherapeutic agents in gastroenteropancreatic neuroendocrine tumor cell lines.
    Georgieva I; Koychev D; Wang Y; Holstein J; Hopfenmüller W; Zeitz M; Grabowski P
    Neuroendocrinology; 2010; 91(2):121-30. PubMed ID: 19923785
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Aurora B kinase inhibition in mitosis: strategies for optimising the use of aurora kinase inhibitors such as AT9283.
    Curry J; Angove H; Fazal L; Lyons J; Reule M; Thompson N; Wallis N
    Cell Cycle; 2009 Jun; 8(12):1921-9. PubMed ID: 19440047
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores.
    Ditchfield C; Johnson VL; Tighe A; Ellston R; Haworth C; Johnson T; Mortlock A; Keen N; Taylor SS
    J Cell Biol; 2003 Apr; 161(2):267-80. PubMed ID: 12719470
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Preclinical evaluation of AMG 900, a novel potent and highly selective pan-aurora kinase inhibitor with activity in taxane-resistant tumor cell lines.
    Payton M; Bush TL; Chung G; Ziegler B; Eden P; McElroy P; Ross S; Cee VJ; Deak HL; Hodous BL; Nguyen HN; Olivieri PR; Romero K; Schenkel LB; Bak A; Stanton M; Dussault I; Patel VF; Geuns-Meyer S; Radinsky R; Kendall RL
    Cancer Res; 2010 Dec; 70(23):9846-54. PubMed ID: 20935223
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of Aurora kinases enhances chemosensitivity to temozolomide and causes radiosensitization in glioblastoma cells.
    Borges KS; Castro-Gamero AM; Moreno DA; da Silva Silveira V; Brassesco MS; de Paula Queiroz RG; de Oliveira HF; Carlotti CG; Scrideli CA; Tone LG
    J Cancer Res Clin Oncol; 2012 Mar; 138(3):405-14. PubMed ID: 22160182
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evolution of resistance to Aurora kinase B inhibitors in leukaemia cells.
    Failes TW; Mitic G; Abdel-Halim H; Po'uha ST; Liu M; Hibbs DE; Kavallaris M
    PLoS One; 2012; 7(2):e30734. PubMed ID: 22359551
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The induction of polyploidy or apoptosis by the Aurora A kinase inhibitor MK8745 is p53-dependent.
    Nair JS; Ho AL; Schwartz GK
    Cell Cycle; 2012 Feb; 11(4):807-17. PubMed ID: 22293494
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Short and long-term tumor cell responses to Aurora kinase inhibitors.
    Dreier MR; Grabovich AZ; Katusin JD; Taylor WR
    Exp Cell Res; 2009 Apr; 315(7):1085-99. PubMed ID: 19233169
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Aurora B kinase regulates the postmitotic endoreduplication checkpoint via phosphorylation of the retinoblastoma protein at serine 780.
    Nair JS; Ho AL; Tse AN; Coward J; Cheema H; Ambrosini G; Keen N; Schwartz GK
    Mol Biol Cell; 2009 Apr; 20(8):2218-28. PubMed ID: 19225156
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tetraploidization increases sensitivity to Aurora B kinase inhibition.
    Marxer M; Foucar CE; Man WY; Chen Y; Ma HT; Poon RY
    Cell Cycle; 2012 Jul; 11(13):2567-77. PubMed ID: 22722494
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mitotic requirement for aurora A kinase is bypassed in the absence of aurora B kinase.
    Yang H; Burke T; Dempsey J; Diaz B; Collins E; Toth J; Beckmann R; Ye X
    FEBS Lett; 2005 Jun; 579(16):3385-91. PubMed ID: 15922328
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibitor of Aurora Kinase B Induces Differentially Cell Death and Polyploidy via DNA Damage Response Pathways in Neurological Malignancy: Shedding New Light on the Challenge of Resistance to AZD1152-HQPA.
    Zekri A; Ghaffari SH; Yaghmaie M; Estiar MA; Alimoghaddam K; Modarressi MH; Ghavamzadeh A
    Mol Neurobiol; 2016 Apr; 53(3):1808-1823. PubMed ID: 25752998
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Predictive biomarkers of sensitivity to the aurora and angiogenic kinase inhibitor ENMD-2076 in preclinical breast cancer models.
    Diamond JR; Eckhardt SG; Tan AC; Newton TP; Selby HM; Brunkow KL; Kachaeva MI; Varella-Garcia M; Pitts TM; Bray MR; Fletcher GC; Tentler JJ
    Clin Cancer Res; 2013 Jan; 19(1):291-303. PubMed ID: 23136197
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Aurora kinase inhibitor AZD1152 negatively affects the growth and survival of HTLV-1-infected T lymphocytes in vitro.
    Tomita M; Tanaka Y; Mori N
    Int J Cancer; 2010 Oct; 127(7):1584-94. PubMed ID: 20091867
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.