These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

188 related articles for article (PubMed ID: 20961378)

  • 1. Nuclear envelope alterations generate an aging-like epigenetic pattern in mice deficient in Zmpste24 metalloprotease.
    Osorio FG; Varela I; Lara E; Puente XS; Espada J; Santoro R; Freije JM; Fraga MF; López-Otín C
    Aging Cell; 2010 Dec; 9(6):947-57. PubMed ID: 20961378
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation.
    Varela I; Cadiñanos J; Pendás AM; Gutiérrez-Fernández A; Folgueras AR; Sánchez LM; Zhou Z; Rodríguez FJ; Stewart CL; Vega JA; Tryggvason K; Freije JM; López-Otín C
    Nature; 2005 Sep; 437(7058):564-8. PubMed ID: 16079796
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient mice.
    Krishnan V; Chow MZ; Wang Z; Zhang L; Liu B; Liu X; Zhou Z
    Proc Natl Acad Sci U S A; 2011 Jul; 108(30):12325-30. PubMed ID: 21746928
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Prelamin A and ZMPSTE24 in premature and physiological aging.
    Worman HJ; Michaelis S
    Nucleus; 2023 Dec; 14(1):2270345. PubMed ID: 37885131
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ZMPSTE24, an integral membrane zinc metalloprotease with a connection to progeroid disorders.
    Barrowman J; Michaelis S
    Biol Chem; 2009 Aug; 390(8):761-73. PubMed ID: 19453269
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans with progeroid syndromes.
    Toth JI; Yang SH; Qiao X; Beigneux AP; Gelb MH; Moulson CL; Miner JH; Young SG; Fong LG
    Proc Natl Acad Sci U S A; 2005 Sep; 102(36):12873-8. PubMed ID: 16129834
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A homozygous ZMPSTE24 null mutation in combination with a heterozygous mutation in the LMNA gene causes Hutchinson-Gilford progeria syndrome (HGPS): insights into the pathophysiology of HGPS.
    Denecke J; Brune T; Feldhaus T; Robenek H; Kranz C; Auchus RJ; Agarwal AK; Marquardt T
    Hum Mutat; 2006 Jun; 27(6):524-31. PubMed ID: 16671095
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Heterozygosity for Lmna deficiency eliminates the progeria-like phenotypes in Zmpste24-deficient mice.
    Fong LG; Ng JK; Meta M; Coté N; Yang SH; Stewart CL; Sullivan T; Burghardt A; Majumdar S; Reue K; Bergo MO; Young SG
    Proc Natl Acad Sci U S A; 2004 Dec; 101(52):18111-6. PubMed ID: 15608054
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A humanized yeast system to analyze cleavage of prelamin A by ZMPSTE24.
    Spear ED; Alford RF; Babatz TD; Wood KM; Mossberg OW; Odinammadu K; Shilagardi K; Gray JJ; Michaelis S
    Methods; 2019 Mar; 157():47-55. PubMed ID: 30625386
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Abnormal nuclear morphology is independent of longevity in a zmpste24-deficient fish model of Hutchinson-Gilford progeria syndrome (HGPS).
    Tonoyama Y; Shinya M; Toyoda A; Kitano T; Oga A; Nishimaki T; Katsumura T; Oota H; Wan MT; Yip BWP; Helen MOL; Chisada S; Deguchi T; Au DWT; Naruse K; Kamei Y; Taniguchi Y
    Comp Biochem Physiol C Toxicol Pharmacol; 2018 Jul; 209():54-62. PubMed ID: 29567411
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cell autonomous and systemic factors in progeria development.
    Osorio FG; Ugalde AP; Mariño G; Puente XS; Freije JM; López-Otín C
    Biochem Soc Trans; 2011 Dec; 39(6):1710-4. PubMed ID: 22103512
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice.
    Pendás AM; Zhou Z; Cadiñanos J; Freije JM; Wang J; Hultenby K; Astudillo A; Wernerson A; Rodríguez F; Tryggvason K; López-Otín C
    Nat Genet; 2002 May; 31(1):94-9. PubMed ID: 11923874
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Proteomic profiling of adipose tissue from Zmpste24-/- mice, a model of lipodystrophy and premature aging, reveals major changes in mitochondrial function and vimentin processing.
    Peinado JR; Quirós PM; Pulido MR; Mariño G; Martínez-Chantar ML; Vázquez-Martínez R; Freije JM; López-Otín C; Malagón MM
    Mol Cell Proteomics; 2011 Nov; 10(11):M111.008094. PubMed ID: 21828285
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MicroRNA-141-3p plays a role in human mesenchymal stem cell aging by directly targeting ZMPSTE24.
    Yu KR; Lee S; Jung JW; Hong IS; Kim HS; Seo Y; Shin TH; Kang KS
    J Cell Sci; 2013 Dec; 126(Pt 23):5422-31. PubMed ID: 24101728
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Loss of ZMPSTE24 (FACE-1) causes autosomal recessive restrictive dermopathy and accumulation of Lamin A precursors.
    Navarro CL; Cadiñanos J; De Sandre-Giovannoli A; Bernard R; Courrier S; Boccaccio I; Boyer A; Kleijer WJ; Wagner A; Giuliano F; Beemer FA; Freije JM; Cau P; Hennekam RC; López-Otín C; Badens C; Lévy N
    Hum Mol Genet; 2005 Jun; 14(11):1503-13. PubMed ID: 15843403
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Homozygous and compound heterozygous mutations in ZMPSTE24 cause the laminopathy restrictive dermopathy.
    Moulson CL; Go G; Gardner JM; van der Wal AC; Smitt JH; van Hagen JM; Miner JH
    J Invest Dermatol; 2005 Nov; 125(5):913-9. PubMed ID: 16297189
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging.
    Varela I; Pereira S; Ugalde AP; Navarro CL; Suárez MF; Cau P; Cadiñanos J; Osorio FG; Foray N; Cobo J; de Carlos F; Lévy N; Freije JM; López-Otín C
    Nat Med; 2008 Jul; 14(7):767-72. PubMed ID: 18587406
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Abolishing the prelamin A ZMPSTE24 cleavage site leads to progeroid phenotypes with near-normal longevity in mice.
    Wang Y; Shilagardi K; Hsu T; Odinammadu KO; Maruyama T; Wu W; Lin CS; Damoci CB; Spear ED; Shin JY; Hsu W; Michaelis S; Worman HJ
    Proc Natl Acad Sci U S A; 2022 Mar; 119(9):. PubMed ID: 35197292
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MicroRNA transcriptome analysis identifies miR-365 as a novel negative regulator of cell proliferation in Zmpste24-deficient mouse embryonic fibroblasts.
    Xiong XD; Jung HJ; Gombar S; Park JY; Zhang CL; Zheng H; Ruan J; Li JB; Kaeberlein M; Kennedy BK; Zhou Z; Liu X; Suh Y
    Mutat Res; 2015 Jul; 777():69-78. PubMed ID: 25983189
    [TBL] [Abstract][Full Text] [Related]  

  • 20.
    Spear ED; Hsu ET; Nie L; Carpenter EP; Hrycyna CA; Michaelis S
    Dis Model Mech; 2018 Jul; 11(7):. PubMed ID: 29794150
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.