BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

324 related articles for article (PubMed ID: 20961996)

  • 1. Combinatorial regulation of neuroblastoma tumor progression by N-Myc and hypoxia inducible factor HIF-1alpha.
    Qing G; Skuli N; Mayes PA; Pawel B; Martinez D; Maris JM; Simon MC
    Cancer Res; 2010 Dec; 70(24):10351-61. PubMed ID: 20961996
    [TBL] [Abstract][Full Text] [Related]  

  • 2. LDHA in Neuroblastoma Is Associated with Poor Outcome and Its Depletion Decreases Neuroblastoma Growth Independent of Aerobic Glycolysis.
    Dorneburg C; Fischer M; Barth TFE; Mueller-Klieser W; Hero B; Gecht J; Carter DR; de Preter K; Mayer B; Christner L; Speleman F; Marshall GM; Debatin KM; Beltinger C
    Clin Cancer Res; 2018 Nov; 24(22):5772-5783. PubMed ID: 29925504
    [No Abstract]   [Full Text] [Related]  

  • 3. Hypoxia-Dependent Expression of TG2 Isoforms in Neuroblastoma Cells as Consequence of Different MYCN Amplification Status.
    Currò M; Ferlazzo N; Giunta ML; Montalto AS; Russo T; Arena S; Impellizzeri P; Caccamo D; Romeo C; Ientile R
    Int J Mol Sci; 2020 Feb; 21(4):. PubMed ID: 32085516
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MYCN and HIF-1 directly regulate
    Hains AE; Uppal S; Cao JZ; Salwen HR; Applebaum MA; Cohn SL; Godley LA
    Epigenetics; 2022 Dec; 17(13):2056-2074. PubMed ID: 35942521
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Silencing gastrin-releasing peptide receptor suppresses key regulators of aerobic glycolysis in neuroblastoma cells.
    Rellinger EJ; Romain C; Choi S; Qiao J; Chung DH
    Pediatr Blood Cancer; 2015 Apr; 62(4):581-6. PubMed ID: 25630799
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Recruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma: HIF-2alpha promotes an aggressive phenotype.
    Holmquist-Mengelbier L; Fredlund E; Löfstedt T; Noguera R; Navarro S; Nilsson H; Pietras A; Vallon-Christersson J; Borg A; Gradin K; Poellinger L; Påhlman S
    Cancer Cell; 2006 Nov; 10(5):413-23. PubMed ID: 17097563
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MYCN and MYC regulate tumor proliferation and tumorigenesis directly through BMI1 in human neuroblastomas.
    Huang R; Cheung NK; Vider J; Cheung IY; Gerald WL; Tickoo SK; Holland EC; Blasberg RG
    FASEB J; 2011 Dec; 25(12):4138-49. PubMed ID: 21856782
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas.
    Westermann F; Muth D; Benner A; Bauer T; Henrich KO; Oberthuer A; Brors B; Beissbarth T; Vandesompele J; Pattyn F; Hero B; König R; Fischer M; Schwab M
    Genome Biol; 2008 Oct; 9(10):R150. PubMed ID: 18851746
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cetuximab reverses the Warburg effect by inhibiting HIF-1-regulated LDH-A.
    Lu H; Li X; Luo Z; Liu J; Fan Z
    Mol Cancer Ther; 2013 Oct; 12(10):2187-99. PubMed ID: 23920275
    [TBL] [Abstract][Full Text] [Related]  

  • 10. mtDNA as a Mediator for Expression of Hypoxia-Inducible Factor 1α and ROS in Hypoxic Neuroblastoma Cells.
    Kuo CW; Tsai MH; Lin TK; Tiao MM; Wang PW; Chuang JH; Chen SD; Liou CW
    Int J Mol Sci; 2017 Jun; 18(6):. PubMed ID: 28590414
    [TBL] [Abstract][Full Text] [Related]  

  • 11. HIF-2alpha expression in human fetal paraganglia and neuroblastoma: relation to sympathetic differentiation, glucose deficiency, and hypoxia.
    Nilsson H; Jögi A; Beckman S; Harris AL; Poellinger L; Påhlman S
    Exp Cell Res; 2005 Feb; 303(2):447-56. PubMed ID: 15652356
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1alpha and -2alpha.
    Puppo M; Battaglia F; Ottaviano C; Delfino S; Ribatti D; Varesio L; Bosco MC
    Mol Cancer Ther; 2008 Jul; 7(7):1974-84. PubMed ID: 18645007
    [TBL] [Abstract][Full Text] [Related]  

  • 13. FX11 inhibits aerobic glycolysis and growth of neuroblastoma cells.
    Rellinger EJ; Craig BT; Alvarez AL; Dusek HL; Kim KW; Qiao J; Chung DH
    Surgery; 2017 Mar; 161(3):747-752. PubMed ID: 27919448
    [TBL] [Abstract][Full Text] [Related]  

  • 14. HIF1/2α mediates hypoxia-induced LDHA expression in human pancreatic cancer cells.
    Cui XG; Han ZT; He SH; Wu XD; Chen TR; Shao CH; Chen DL; Su N; Chen YM; Wang T; Wang J; Song DW; Yan WJ; Yang XH; Liu T; Wei HF; Xiao J
    Oncotarget; 2017 Apr; 8(15):24840-24852. PubMed ID: 28193910
    [TBL] [Abstract][Full Text] [Related]  

  • 15. HIF-1alpha induces MXI1 by alternate promoter usage in human neuroblastoma cells.
    Löfstedt T; Fredlund E; Noguera R; Navarro S; Holmquist-Mengelbier L; Beckman S; Påhlman S; Axelson H
    Exp Cell Res; 2009 Jul; 315(11):1924-36. PubMed ID: 19254710
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A splice variant of the human ion channel TRPM2 modulates neuroblastoma tumor growth through hypoxia-inducible factor (HIF)-1/2α.
    Chen SJ; Hoffman NE; Shanmughapriya S; Bao L; Keefer K; Conrad K; Merali S; Takahashi Y; Abraham T; Hirschler-Laszkiewicz I; Wang J; Zhang XQ; Song J; Barrero C; Shi Y; Kawasawa YI; Bayerl M; Sun T; Barbour M; Wang HG; Madesh M; Cheung JY; Miller BA
    J Biol Chem; 2014 Dec; 289(52):36284-302. PubMed ID: 25391657
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Glycolytic inhibitor 2-deoxyglucose simultaneously targets cancer and endothelial cells to suppress neuroblastoma growth in mice.
    Huang CC; Wang SY; Lin LL; Wang PW; Chen TY; Hsu WM; Lin TK; Liou CW; Chuang JH
    Dis Model Mech; 2015 Oct; 8(10):1247-54. PubMed ID: 26398947
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Immunohistochemical analysis of PDK1, PHD3 and HIF-1α expression defines the hypoxic status of neuroblastoma tumors.
    Ognibene M; Cangelosi D; Morini M; Segalerba D; Bosco MC; Sementa AR; Eva A; Varesio L
    PLoS One; 2017; 12(11):e0187206. PubMed ID: 29117193
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 2-Methoxyestradiol synergizes with sorafenib to suppress hepatocellular carcinoma by simultaneously dysregulating hypoxia-inducible factor-1 and -2.
    Ma L; Li G; Zhu H; Dong X; Zhao D; Jiang X; Li J; Qiao H; Ni S; Sun X
    Cancer Lett; 2014 Dec; 355(1):96-105. PubMed ID: 25218350
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: implications for antiangiogenic mechanisms of multikinase inhibitors.
    Nilsson MB; Zage PE; Zeng L; Xu L; Cascone T; Wu HK; Saigal B; Zweidler-McKay PA; Heymach JV
    Oncogene; 2010 May; 29(20):2938-49. PubMed ID: 20208561
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.