237 related articles for article (PubMed ID: 20962061)
1. Organic cation transporter-mediated renal secretion of ipratropium and tiotropium in rats and humans.
Nakanishi T; Haruta T; Shirasaka Y; Tamai I
Drug Metab Dispos; 2011 Jan; 39(1):117-22. PubMed ID: 20962061
[TBL] [Abstract][Full Text] [Related]
2. Transport of the dopamine D2 agonist pramipexole by rat organic cation transporters OCT1 and OCT2 in kidney.
Ishiguro N; Saito A; Yokoyama K; Morikawa M; Igarashi T; Tamai I
Drug Metab Dispos; 2005 Apr; 33(4):495-9. PubMed ID: 15640376
[TBL] [Abstract][Full Text] [Related]
3. Transport of ipratropium, an anti-chronic obstructive pulmonary disease drug, is mediated by organic cation/carnitine transporters in human bronchial epithelial cells: implications for carrier-mediated pulmonary absorption.
Nakamura T; Nakanishi T; Haruta T; Shirasaka Y; Keogh JP; Tamai I
Mol Pharm; 2010 Feb; 7(1):187-95. PubMed ID: 20020740
[TBL] [Abstract][Full Text] [Related]
4. Oxaliplatin transport mediated by organic cation/carnitine transporters OCTN1 and OCTN2 in overexpressing human embryonic kidney 293 cells and rat dorsal root ganglion neurons.
Jong NN; Nakanishi T; Liu JJ; Tamai I; McKeage MJ
J Pharmacol Exp Ther; 2011 Aug; 338(2):537-47. PubMed ID: 21606177
[TBL] [Abstract][Full Text] [Related]
5. Comparison of the kinetic characteristics of inhibitory effects exerted by biguanides and H2-blockers on human and rat organic cation transporter-mediated transport: Insight into the development of drug candidates.
Umehara KI; Iwatsubo T; Noguchi K; Kamimura H
Xenobiotica; 2007 Jun; 37(6):618-34. PubMed ID: 17614008
[TBL] [Abstract][Full Text] [Related]
6. Identification of human metabolites of (-)-N-{2-[(R)-3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a novel If channel inhibitor, and investigation of the transporter-mediated renal and hepatic excretion of these metabolites.
Umehara K; Shirai N; Iwatsubo T; Noguchi K; Usui T; Kamimura H
Drug Metab Dispos; 2009 Aug; 37(8):1646-57. PubMed ID: 19439489
[TBL] [Abstract][Full Text] [Related]
7. Organic cation transporters OCT1, 2, and 3 mediate high-affinity transport of the mutagenic vital dye ethidium in the kidney proximal tubule.
Lee WK; Reichold M; Edemir B; Ciarimboli G; Warth R; Koepsell H; Thévenod F
Am J Physiol Renal Physiol; 2009 Jun; 296(6):F1504-13. PubMed ID: 19357179
[TBL] [Abstract][Full Text] [Related]
8. Subtype-specific affinity for corticosterone of rat organic cation transporters rOCT1 and rOCT2 depends on three amino acids within the substrate binding region.
Gorboulev V; Shatskaya N; Volk C; Koepsell H
Mol Pharmacol; 2005 May; 67(5):1612-9. PubMed ID: 15662045
[TBL] [Abstract][Full Text] [Related]
9. Substrate- and cell contact-dependent inhibitor affinity of human organic cation transporter 2: studies with two classical organic cation substrates and the novel substrate cd2+.
Thévenod F; Ciarimboli G; Leistner M; Wolff NA; Lee WK; Schatz I; Keller T; Al-Monajjed R; Gorboulev V; Koepsell H
Mol Pharm; 2013 Aug; 10(8):3045-56. PubMed ID: 23763587
[TBL] [Abstract][Full Text] [Related]
10. Functional involvement of the organic cation transporter 2 (rOct2) in the renal uptake of organic cations in rats.
Umehara KI; Iwatsubo T; Noguchi K; Kamimura H
J Int Med Res; 2008; 36(1):123-36. PubMed ID: 18230276
[TBL] [Abstract][Full Text] [Related]
11. Association between tubular toxicity of cisplatin and expression of organic cation transporter rOCT2 (Slc22a2) in the rat.
Yonezawa A; Masuda S; Nishihara K; Yano I; Katsura T; Inui K
Biochem Pharmacol; 2005 Dec; 70(12):1823-31. PubMed ID: 16242669
[TBL] [Abstract][Full Text] [Related]
12. The organic cation transporters rOCT1 and hOCT2 are inhibited by cGMP.
Schlatter E; Mönnich V; Cetinkaya I; Mehrens T; Ciarimboli G; Hirsch JR; Popp C; Koepsell H
J Membr Biol; 2002 Oct; 189(3):237-44. PubMed ID: 12395288
[TBL] [Abstract][Full Text] [Related]
13. Effect of cationic drugs on the transporting activity of human and rat OCT/Oct 1-3 in vitro and implications for drug-drug interactions.
Umehara KI; Iwatsubo T; Noguchi K; Usui T; Kamimura H
Xenobiotica; 2008 Sep; 38(9):1203-18. PubMed ID: 18686197
[TBL] [Abstract][Full Text] [Related]
14. Restored expression and activity of organic ion transporters rOAT1, rOAT3 and rOCT2 after hyperuricemia in the rat kidney.
Habu Y; Yano I; Okuda M; Fukatsu A; Inui K
Biochem Pharmacol; 2005 Mar; 69(6):993-9. PubMed ID: 15748710
[TBL] [Abstract][Full Text] [Related]
15. Functional characterization of the human organic cation transporter 2 variant p.270Ala>Ser.
Zolk O; Solbach TF; König J; Fromm MF
Drug Metab Dispos; 2009 Jun; 37(6):1312-8. PubMed ID: 19251820
[TBL] [Abstract][Full Text] [Related]
16. The mitochondrial fluorescent dye rhodamine 123 is a high-affinity substrate for organic cation transporters (OCTs) 1 and 2.
Jouan E; Le Vee M; Denizot C; Da Violante G; Fardel O
Fundam Clin Pharmacol; 2014 Feb; 28(1):65-77. PubMed ID: 22913740
[TBL] [Abstract][Full Text] [Related]
17. Nitric oxide down-regulates the expression of organic cation transporters (OCT) 1 and 2 in rat kidney during endotoxemia.
Heemskerk S; Wouterse AC; Russel FG; Masereeuw R
Eur J Pharmacol; 2008 Apr; 584(2-3):390-7. PubMed ID: 18313662
[TBL] [Abstract][Full Text] [Related]
18. Relevance of the organic cation transporters 1 and 2 for antiretroviral drug therapy in human immunodeficiency virus infection.
Jung N; Lehmann C; Rubbert A; Knispel M; Hartmann P; van Lunzen J; Stellbrink HJ; Faetkenheuer G; Taubert D
Drug Metab Dispos; 2008 Aug; 36(8):1616-23. PubMed ID: 18490433
[TBL] [Abstract][Full Text] [Related]
19. Inhibitory and facilitory actions of isocyanine derivatives at human and rat organic cation transporters 1, 2 and 3: a comparison to human alpha 1- and alpha 2-adrenoceptor subtypes.
Amphoux A; Millan MJ; Cordi A; Bönisch H; Vialou V; Mannoury la Cour C; Dupuis DS; Giros B; Gautron S
Eur J Pharmacol; 2010 May; 634(1-3):1-9. PubMed ID: 20170649
[TBL] [Abstract][Full Text] [Related]
20. Tropane alkaloids as substrates and inhibitors of human organic cation transporters of the SLC22 (OCT) and the SLC47 (MATE) families.
Chen J; Brockmöller J; Seitz T; König J; Chen X; Tzvetkov MV
Biol Chem; 2017 Feb; 398(2):237-249. PubMed ID: 27676604
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
