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5. The targeted oral, once-daily phosphodiesterase 4 inhibitor roflumilast and the leukotriene receptor antagonist montelukast do not exhibit significant pharmacokinetic interactions. Böhmer GM; Nassr N; Wenger M; Hünnemeyer A; Lahu G; Templin S; Gleiter CH; Hermann R J Clin Pharmacol; 2009 Apr; 49(4):389-97. PubMed ID: 19318692 [TBL] [Abstract][Full Text] [Related]
6. Absence of pharmacokinetic interaction between roflumilast and digoxin in healthy adults. Eckermann G; Lahu G; Nassr N; Bethke TD J Clin Pharmacol; 2012 Feb; 52(2):251-7. PubMed ID: 21257799 [TBL] [Abstract][Full Text] [Related]
7. Effect of fluvoxamine on the pharmacokinetics of roflumilast and roflumilast N-oxide. von Richter O; Lahu G; Huennemeyer A; Herzog R; Zech K; Hermann R Clin Pharmacokinet; 2007; 46(7):613-22. PubMed ID: 17596106 [TBL] [Abstract][Full Text] [Related]
8. Single-dose pharmacokinetics of roflumilast in children and adolescents. Neville KA; Szefler SJ; Abdel-Rahman SM; Lahu G; Zech K; Herzog R; Bethke TD; Gleason MC; Kearns GL J Clin Pharmacol; 2008 Aug; 48(8):978-85. PubMed ID: 18508947 [TBL] [Abstract][Full Text] [Related]
9. No dose adjustment on coadministration of the PDE4 inhibitor roflumilast with a weak CYP3A, CYP1A2, and CYP2C19 inhibitor: an investigation using cimetidine. Böhmer GM; Gleiter CH; Mörike K; Nassr N; Walz A; Lahu G J Clin Pharmacol; 2011 Apr; 51(4):594-602. PubMed ID: 20484614 [TBL] [Abstract][Full Text] [Related]
10. Steady-state pharmacokinetics of roflumilast and roflumilast N-oxide in patients with mild and moderate liver cirrhosis. Hermann R; Nassr N; Lahu G; Péterfai E; Knoerzer D; Herzog R; Zech K; de Mey C Clin Pharmacokinet; 2007; 46(5):403-16. PubMed ID: 17465639 [TBL] [Abstract][Full Text] [Related]
11. Roflumilast, a once-daily oral phosphodiesterase 4 inhibitor, lacks relevant pharmacokinetic interactions with inhaled salbutamol when co-administered in healthy subjects. Bethke TD; Giessmann T; Westphal K; Weinbrenner A; Hauns B; Hauschke D; David M; Lahu G; Zech K; Hermann R; Siegmund W Int J Clin Pharmacol Ther; 2006 Nov; 44(11):572-9. PubMed ID: 17176624 [TBL] [Abstract][Full Text] [Related]
12. Effect of single and repeated doses of ketoconazole on the pharmacokinetics of roflumilast and roflumilast N-oxide. Lahu G; Huennemeyer A; von Richter O; Hermann R; Herzog R; McCracken N; Zech K J Clin Pharmacol; 2008 Nov; 48(11):1339-49. PubMed ID: 18757786 [TBL] [Abstract][Full Text] [Related]
13. Magnesium hydroxide/aluminium hydroxide-containing antacid does not affect the pharmacokinetics of the targeted phosphodiesterase 4 inhibitor roflumilast. Nassr N; Lahu G; Hünnemeyer A; von Richter O; Knoerzer D; Reutter F; Zech K; Hermann R J Clin Pharmacol; 2007 May; 47(5):660-6. PubMed ID: 17374735 [No Abstract] [Full Text] [Related]
14. Influence of renal impairment on the pharmacokinetics of oral roflumilast: an open-label, parallel-group, single-center study. Bethke TD; Hartmann M; Hünnemeyer A; Lahu G; Gleiter CH Int J Clin Pharmacol Ther; 2011 Aug; 49(8):491-9. PubMed ID: 21781649 [TBL] [Abstract][Full Text] [Related]
15. Effect of steady-state enoxacin on single-dose pharmacokinetics of roflumilast and roflumilast N-oxide. Lahu G; Nassr N; Herzog R; Elmlinger M; Ruth P; Hinder M; Huennemeyer A J Clin Pharmacol; 2011 Apr; 51(4):586-93. PubMed ID: 20466871 [TBL] [Abstract][Full Text] [Related]
16. Supra-therapeutic doses of roflumilast have no effect on cardiac repolarization in healthy subjects. Huennemeyer A; Nassr N; Bredenbröker D; Lahu G Expert Opin Drug Saf; 2011 Jul; 10(4):509-19. PubMed ID: 21585288 [TBL] [Abstract][Full Text] [Related]
17. Pharmacokinetics of single- and multiple-dose roflumilast: an open-label, three-way crossover study in healthy Chinese volunteers. Huang J; Fu CX; Yang XY; Cui C; Yang S; Kuang Y; Guo CX; Hu P; Pei Q; Yang GP Drug Des Devel Ther; 2018; 12():4047-4057. PubMed ID: 30538429 [TBL] [Abstract][Full Text] [Related]
18. Pharmacokinetics of Roflumilast and Its Active Metabolite Roflumilast N-Oxide in Healthy Chinese Subjects After Single and Multiple Oral Doses. Li Q; Wang Y; Liu L; Ma P; Ding L Eur J Drug Metab Pharmacokinet; 2017 Jun; 42(3):371-381. PubMed ID: 27306372 [TBL] [Abstract][Full Text] [Related]
19. Simultaneous quantification and pharmacokinetic evaluation of roflumilast and its N-oxide in cynomolgus monkey plasma by LC-MS/MS method. Qu H; Zhang K; Fu C; Qiu F Biomed Chromatogr; 2021 Feb; 35(2):e4973. PubMed ID: 32840886 [TBL] [Abstract][Full Text] [Related]
20. Lack of a pharmacokinetic interaction between steady-state roflumilast and single-dose midazolam in healthy subjects. Nassr N; Lahu G; von Richter O; Reutter F; Knoerzer D; Zech K; Erb KA; Schug B; Blume H; Hermann R Br J Clin Pharmacol; 2007 Mar; 63(3):365-70. PubMed ID: 16981901 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]