BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

364 related articles for article (PubMed ID: 20970440)

  • 1. Application of toxicogenomics in hepatic systems toxicology for risk assessment: acetaminophen as a case study.
    Kienhuis AS; Bessems JG; Pennings JL; Driessen M; Luijten M; van Delft JH; Peijnenburg AA; van der Ven LT
    Toxicol Appl Pharmacol; 2011 Jan; 250(2):96-107. PubMed ID: 20970440
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Parallelogram approach using rat-human in vitro and rat in vivo toxicogenomics predicts acetaminophen-induced hepatotoxicity in humans.
    Kienhuis AS; van de Poll MC; Wortelboer H; van Herwijnen M; Gottschalk R; Dejong CH; Boorsma A; Paules RS; Kleinjans JC; Stierum RH; van Delft JH
    Toxicol Sci; 2009 Feb; 107(2):544-52. PubMed ID: 19008212
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Utilizing toxicogenomic data to understand chemical mechanism of action in risk assessment.
    Wilson VS; Keshava N; Hester S; Segal D; Chiu W; Thompson CM; Euling SY
    Toxicol Appl Pharmacol; 2013 Sep; 271(3):299-308. PubMed ID: 21295051
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Toxicogenomics-based prediction of acetaminophen-induced liver injury using human hepatic cell systems.
    Rodrigues RM; Heymans A; De Boe V; Sachinidis A; Chaudhari U; Govaere O; Roskams T; Vanhaecke T; Rogiers V; De Kock J
    Toxicol Lett; 2016 Jan; 240(1):50-9. PubMed ID: 26497421
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Systems toxicology: applications of toxicogenomics, transcriptomics, proteomics and metabolomics in toxicology.
    Heijne WH; Kienhuis AS; van Ommen B; Stierum RH; Groten JP
    Expert Rev Proteomics; 2005 Oct; 2(5):767-80. PubMed ID: 16209655
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Integrating toxicogenomics into human health risk assessment: lessons learned from the benzo[a]pyrene case study.
    Chepelev NL; Moffat ID; Labib S; Bourdon-Lacombe J; Kuo B; Buick JK; Lemieux F; Malik AI; Halappanavar S; Williams A; Yauk CL
    Crit Rev Toxicol; 2015 Jan; 45(1):44-52. PubMed ID: 25605027
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Current and future use of genomics data in toxicology: opportunities and challenges for regulatory applications.
    Goetz AK; Singh BP; Battalora M; Breier JM; Bailey JP; Chukwudebe AC; Janus ER
    Regul Toxicol Pharmacol; 2011 Nov; 61(2):141-53. PubMed ID: 21840362
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Toxicogenomics for the prediction of toxicity related to herbs from traditional Chinese medicine.
    Youns M; Hoheisel JD; Efferth T
    Planta Med; 2010 Dec; 76(17):2019-25. PubMed ID: 20957595
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Development of novel tools for the in vitro investigation of drug-induced liver injury.
    Jiang J; Wolters JE; van Breda SG; Kleinjans JC; de Kok TM
    Expert Opin Drug Metab Toxicol; 2015; 11(10):1523-37. PubMed ID: 26155718
    [TBL] [Abstract][Full Text] [Related]  

  • 10. dbZach toxicogenomic information management system.
    Burgoon LD; Zacharewski TR
    Pharmacogenomics; 2007 Mar; 8(3):287-91. PubMed ID: 17324117
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The use of genomics in model in vitro systems.
    Casciano DA
    Adv Exp Med Biol; 2012; 745():210-20. PubMed ID: 22437820
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Contribution of new technologies to characterization and prediction of adverse effects.
    Rouquié D; Heneweer M; Botham J; Ketelslegers H; Markell L; Pfister T; Steiling W; Strauss V; Hennes C
    Crit Rev Toxicol; 2015 Feb; 45(2):172-83. PubMed ID: 25615431
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Utilization of causal reasoning of hepatic gene expression in rats to identify molecular pathways of idiosyncratic drug-induced liver injury.
    Laifenfeld D; Qiu L; Swiss R; Park J; Macoritto M; Will Y; Younis HS; Lawton M
    Toxicol Sci; 2014 Jan; 137(1):234-48. PubMed ID: 24136188
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Toxicogenomics: regulatory perspective on current position.
    Battershill JM
    Hum Exp Toxicol; 2005 Jan; 24(1):35-40. PubMed ID: 15727054
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The human hepatocyte TXG-MAPr: gene co-expression network modules to support mechanism-based risk assessment.
    Callegaro G; Kunnen SJ; Trairatphisan P; Grosdidier S; Niemeijer M; den Hollander W; Guney E; Piñero Gonzalez J; Furlong L; Webster YW; Saez-Rodriguez J; Sutherland JJ; Mollon J; Stevens JL; van de Water B
    Arch Toxicol; 2021 Dec; 95(12):3745-3775. PubMed ID: 34626214
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Application of toxicogenomics to toxicology: basic concepts in the analysis of microarray data.
    Irwin RD; Boorman GA; Cunningham ML; Heinloth AN; Malarkey DE; Paules RS
    Toxicol Pathol; 2004; 32 Suppl 1():72-83. PubMed ID: 15209406
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Use of toxicogenomics to understand mechanisms of drug-induced hepatotoxicity during drug discovery and development.
    Blomme EA; Yang Y; Waring JF
    Toxicol Lett; 2009 Apr; 186(1):22-31. PubMed ID: 18996174
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Toxicogenomic profiling of chemically exposed humans in risk assessment.
    McHale CM; Zhang L; Hubbard AE; Smith MT
    Mutat Res; 2010 Dec; 705(3):172-83. PubMed ID: 20382258
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking water.
    Moffat I; Chepelev N; Labib S; Bourdon-Lacombe J; Kuo B; Buick JK; Lemieux F; Williams A; Halappanavar S; Malik A; Luijten M; Aubrecht J; Hyduke DR; Fornace AJ; Swartz CD; Recio L; Yauk CL
    Crit Rev Toxicol; 2015 Jan; 45(1):1-43. PubMed ID: 25605026
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Toxicogenomics concepts and applications to study hepatic effects of food additives and chemicals.
    Stierum R; Heijne W; Kienhuis A; van Ommen B; Groten J
    Toxicol Appl Pharmacol; 2005 Sep; 207(2 Suppl):179-88. PubMed ID: 16139318
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.