BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

369 related articles for article (PubMed ID: 20972333)

  • 21. Oncogenic activating mutations are associated with local copy gain.
    Modrek B; Ge L; Pandita A; Lin E; Mohan S; Yue P; Guerrero S; Lin WM; Pham T; Modrusan Z; Seshagiri S; Stern HM; Waring P; Garraway LA; Chant J; Stokoe D; Cavet G
    Mol Cancer Res; 2009 Aug; 7(8):1244-52. PubMed ID: 19671679
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Significance of KRAS/PAK1/Crk pathway in non-small cell lung cancer oncogenesis.
    Mortazavi F; Lu J; Phan R; Lewis M; Trinidad K; Aljilani A; Pezeshkpour G; Tamanoi F
    BMC Cancer; 2015 May; 15():381. PubMed ID: 25956913
    [TBL] [Abstract][Full Text] [Related]  

  • 23. NOS2 enhances KRAS-induced lung carcinogenesis, inflammation and microRNA-21 expression.
    Okayama H; Saito M; Oue N; Weiss JM; Stauffer J; Takenoshita S; Wiltrout RH; Hussain SP; Harris CC
    Int J Cancer; 2013 Jan; 132(1):9-18. PubMed ID: 22618808
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Mutation of the LXCXE binding cleft of pRb facilitates transformation by ras in vitro but does not promote tumorigenesis in vivo.
    Talluri S; Francis SM; Dick FA
    PLoS One; 2013; 8(8):e72236. PubMed ID: 23936539
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Oncogenic KRAS promotes malignant brain tumors in zebrafish.
    Ju B; Chen W; Orr BA; Spitsbergen JM; Jia S; Eden CJ; Henson HE; Taylor MR
    Mol Cancer; 2015 Feb; 14(1):18. PubMed ID: 25644510
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Scrib heterozygosity predisposes to lung cancer and cooperates with KRas hyperactivation to accelerate lung cancer progression in vivo.
    Elsum IA; Yates LL; Pearson HB; Phesse TJ; Long F; O'Donoghue R; Ernst M; Cullinane C; Humbert PO
    Oncogene; 2014 Nov; 33(48):5523-33. PubMed ID: 24276238
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Phosphorylation at Ser-181 of oncogenic KRAS is required for tumor growth.
    Barceló C; Paco N; Morell M; Alvarez-Moya B; Bota-Rabassedas N; Jaumot M; Vilardell F; Capella G; Agell N
    Cancer Res; 2014 Feb; 74(4):1190-9. PubMed ID: 24371225
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Determination of synthetic lethal interactions in KRAS oncogene-dependent cancer cells reveals novel therapeutic targeting strategies.
    Steckel M; Molina-Arcas M; Weigelt B; Marani M; Warne PH; Kuznetsov H; Kelly G; Saunders B; Howell M; Downward J; Hancock DC
    Cell Res; 2012 Aug; 22(8):1227-45. PubMed ID: 22613949
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Novel AKT1-GLI3-VMP1 pathway mediates KRAS oncogene-induced autophagy in cancer cells.
    Lo Ré AE; Fernández-Barrena MG; Almada LL; Mills LD; Elsawa SF; Lund G; Ropolo A; Molejon MI; Vaccaro MI; Fernandez-Zapico ME
    J Biol Chem; 2012 Jul; 287(30):25325-34. PubMed ID: 22535956
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells.
    Scholl C; Fröhling S; Dunn IF; Schinzel AC; Barbie DA; Kim SY; Silver SJ; Tamayo P; Wadlow RC; Ramaswamy S; Döhner K; Bullinger L; Sandy P; Boehm JS; Root DE; Jacks T; Hahn WC; Gilliland DG
    Cell; 2009 May; 137(5):821-34. PubMed ID: 19490892
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Multiplexed screens identify RAS paralogues HRAS and NRAS as suppressors of KRAS-driven lung cancer growth.
    Tang R; Shuldiner EG; Kelly M; Murray CW; Hebert JD; Andrejka L; Tsai MK; Hughes NW; Parker MI; Cai H; Li YC; Wahl GM; Dunbrack RL; Jackson PK; Petrov DA; Winslow MM
    Nat Cell Biol; 2023 Jan; 25(1):159-169. PubMed ID: 36635501
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Inhibition of TWIST1 leads to activation of oncogene-induced senescence in oncogene-driven non-small cell lung cancer.
    Burns TF; Dobromilskaya I; Murphy SC; Gajula RP; Thiyagarajan S; Chatley SN; Aziz K; Cho YJ; Tran PT; Rudin CM
    Mol Cancer Res; 2013 Apr; 11(4):329-38. PubMed ID: 23364532
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Reduced HRAS G12V-Driven Tumorigenesis of Cell Lines Expressing KRAS C118S.
    Huang L; Counter CM
    PLoS One; 2015; 10(4):e0123918. PubMed ID: 25902334
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Thrombospondin-1 mediates oncogenic Ras-induced senescence in premalignant lung tumors.
    Baek KH; Bhang D; Zaslavsky A; Wang LC; Vachani A; Kim CF; Albelda SM; Evan GI; Ryeom S
    J Clin Invest; 2013 Oct; 123(10):4375-89. PubMed ID: 24018559
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Senescence-associated SIN3B promotes inflammation and pancreatic cancer progression.
    Rielland M; Cantor DJ; Graveline R; Hajdu C; Mara L; Diaz Bde D; Miller G; David G
    J Clin Invest; 2014 May; 124(5):2125-35. PubMed ID: 24691445
    [TBL] [Abstract][Full Text] [Related]  

  • 36. RAGE is essential for oncogenic KRAS-mediated hypoxic signaling in pancreatic cancer.
    Kang R; Hou W; Zhang Q; Chen R; Lee YJ; Bartlett DL; Lotze MT; Tang D; Zeh HJ
    Cell Death Dis; 2014 Oct; 5(10):e1480. PubMed ID: 25341034
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Wnt and Kras signaling-dark siblings in lung cancer.
    Pacheco-Pinedo EC; Morrisey EE
    Oncotarget; 2011 Jul; 2(7):569-74. PubMed ID: 21753228
    [TBL] [Abstract][Full Text] [Related]  

  • 38. TAK1 inhibition promotes apoptosis in KRAS-dependent colon cancers.
    Singh A; Sweeney MF; Yu M; Burger A; Greninger P; Benes C; Haber DA; Settleman J
    Cell; 2012 Feb; 148(4):639-50. PubMed ID: 22341439
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Kruppel-like factor 5 is not required for K-RasG12D lung tumorigenesis, but represses ABCG2 expression and is associated with better disease-specific survival.
    Meyer SE; Hasenstein JR; Baktula A; Velu CS; Xu Y; Wan H; Whitsett JA; Gilks CB; Grimes HL
    Am J Pathol; 2010 Sep; 177(3):1503-13. PubMed ID: 20639455
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Oncogenic KRAS modulates mitochondrial metabolism in human colon cancer cells by inducing HIF-1α and HIF-2α target genes.
    Chun SY; Johnson C; Washburn JG; Cruz-Correa MR; Dang DT; Dang LH
    Mol Cancer; 2010 Nov; 9():293. PubMed ID: 21073737
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 19.