BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 20972709)

  • 21. Impact of somatic PI3K pathway and ERBB family mutations on pathological complete response (pCR) in HER2-positive breast cancer patients who received neoadjuvant HER2-targeted therapies.
    Toomey S; Eustace AJ; Fay J; Sheehan KM; Carr A; Milewska M; Madden SF; Teiserskiene A; Kay EW; O'Donovan N; Gallagher W; Grogan L; Breathnach O; Walshe J; Kelly C; Moulton B; Kennedy MJ; Gullo G; Hill AD; Power C; Duke D; Hambly N; Crown J; Hennessy BT
    Breast Cancer Res; 2017 Jul; 19(1):87. PubMed ID: 28750640
    [TBL] [Abstract][Full Text] [Related]  

  • 22. New strategies in HER2-overexpressing breast cancer: many combinations of targeted drugs available.
    Abramson V; Arteaga CL
    Clin Cancer Res; 2011 Mar; 17(5):952-8. PubMed ID: 21248299
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Multiple molecular mechanisms underlying trastuzumab and lapatinib resistance in JIMT-1 breast cancer cells.
    Köninki K; Barok M; Tanner M; Staff S; Pitkänen J; Hemmilä P; Ilvesaro J; Isola J
    Cancer Lett; 2010 Aug; 294(2):211-9. PubMed ID: 20193978
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Overcoming treatment resistance in HER2-positive breast cancer: potential strategies.
    Puglisi F; Minisini AM; De Angelis C; Arpino G
    Drugs; 2012 Jun; 72(9):1175-93. PubMed ID: 22686613
    [TBL] [Abstract][Full Text] [Related]  

  • 25. MiR-221 promotes trastuzumab-resistance and metastasis in HER2-positive breast cancers by targeting PTEN.
    Ye X; Bai W; Zhu H; Zhang X; Chen Y; Wang L; Yang A; Zhao J; Jia L
    BMB Rep; 2014 May; 47(5):268-73. PubMed ID: 24286315
    [TBL] [Abstract][Full Text] [Related]  

  • 26. HER2-amplified breast cancer: mechanisms of trastuzumab resistance and novel targeted therapies.
    Gajria D; Chandarlapaty S
    Expert Rev Anticancer Ther; 2011 Feb; 11(2):263-75. PubMed ID: 21342044
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Yes1 signaling mediates the resistance to Trastuzumab/Lap atinib in breast cancer.
    Takeda T; Yamamoto H; Kanzaki H; Suzawa K; Yoshioka T; Tomida S; Cui X; Murali R; Namba K; Sato H; Torigoe H; Watanabe M; Shien K; Soh J; Asano H; Tsukuda K; Kitamura Y; Miyoshi S; Sendo T; Toyooka S
    PLoS One; 2017; 12(2):e0171356. PubMed ID: 28158234
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Dacomitinib (PF-00299804), an irreversible Pan-HER inhibitor, inhibits proliferation of HER2-amplified breast cancer cell lines resistant to trastuzumab and lapatinib.
    Kalous O; Conklin D; Desai AJ; O'Brien NA; Ginther C; Anderson L; Cohen DJ; Britten CD; Taylor I; Christensen JG; Slamon DJ; Finn RS
    Mol Cancer Ther; 2012 Sep; 11(9):1978-87. PubMed ID: 22761403
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Evolving strategies for overcoming resistance to HER2-directed therapy: targeting the PI3K/Akt/mTOR pathway.
    Nahta R; O'Regan RM
    Clin Breast Cancer; 2010 Nov; 10 Suppl 3():S72-8. PubMed ID: 21115425
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Association between gain-of-function mutations in PIK3CA and resistance to HER2-targeted agents in HER2-amplified breast cancer cell lines.
    Kataoka Y; Mukohara T; Shimada H; Saijo N; Hirai M; Minami H
    Ann Oncol; 2010 Feb; 21(2):255-262. PubMed ID: 19633047
    [TBL] [Abstract][Full Text] [Related]  

  • 31. [New treatment approaches in breast cancer].
    Spirig C; Thürlimann B; Huober J
    Ther Umsch; 2008 Apr; 65(4):207-10. PubMed ID: 18622912
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Lapatinib induces apoptosis in trastuzumab-resistant breast cancer cells: effects on insulin-like growth factor I signaling.
    Nahta R; Yuan LX; Du Y; Esteva FJ
    Mol Cancer Ther; 2007 Feb; 6(2):667-74. PubMed ID: 17308062
    [TBL] [Abstract][Full Text] [Related]  

  • 33. PI3 kinase activation and response to Trastuzumab Therapy: what's neu with herceptin resistance?
    Park BH; Davidson NE
    Cancer Cell; 2007 Oct; 12(4):297-9. PubMed ID: 17936554
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Mechanisms of Acquired Resistance to Trastuzumab Emtansine in Breast Cancer Cells.
    Li G; Guo J; Shen BQ; Yadav DB; Sliwkowski MX; Crocker LM; Lacap JA; Phillips GDL
    Mol Cancer Ther; 2018 Jul; 17(7):1441-1453. PubMed ID: 29695635
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Mechanisms of disease: understanding resistance to HER2-targeted therapy in human breast cancer.
    Nahta R; Yu D; Hung MC; Hortobagyi GN; Esteva FJ
    Nat Clin Pract Oncol; 2006 May; 3(5):269-80. PubMed ID: 16683005
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Presence of HER4 associates with increased sensitivity to Herceptin in patients with metastatic breast cancer.
    Sassen A; Diermeier-Daucher S; Sieben M; Ortmann O; Hofstaedter F; Schwarz S; Brockhoff G
    Breast Cancer Res; 2009; 11(4):R50. PubMed ID: 19624808
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Beyond trastuzumab: overcoming resistance to targeted HER-2 therapy in breast cancer.
    Bedard PL; de Azambuja E; Cardoso F
    Curr Cancer Drug Targets; 2009 Mar; 9(2):148-62. PubMed ID: 19275756
    [TBL] [Abstract][Full Text] [Related]  

  • 38. [Principles and method of action of targeted therapies].
    Singer CF
    Wien Med Wochenschr; 2010 Nov; 160(19-20):501-5. PubMed ID: 21080269
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Activated phosphoinositide 3-kinase/AKT signaling confers resistance to trastuzumab but not lapatinib.
    O'Brien NA; Browne BC; Chow L; Wang Y; Ginther C; Arboleda J; Duffy MJ; Crown J; O'Donovan N; Slamon DJ
    Mol Cancer Ther; 2010 Jun; 9(6):1489-502. PubMed ID: 20501798
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Trastuzumab and breast cancer: developments and current status.
    Tokunaga E; Oki E; Nishida K; Koga T; Egashira A; Morita M; Kakeji Y; Maehara Y
    Int J Clin Oncol; 2006 Jun; 11(3):199-208. PubMed ID: 16850126
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.