BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

940 related articles for article (PubMed ID: 20978149)

  • 1. Inactivation of the APC gene is constant in adrenocortical tumors from patients with familial adenomatous polyposis but not frequent in sporadic adrenocortical cancers.
    Gaujoux S; Pinson S; Gimenez-Roqueplo AP; Amar L; Ragazzon B; Launay P; Meatchi T; Libé R; Bertagna X; Audebourg A; Zucman-Rossi J; Tissier F; Bertherat J
    Clin Cancer Res; 2010 Nov; 16(21):5133-41. PubMed ID: 20978149
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ovarian steroid cell tumor with biallelic adenomatous polyposis coli inactivation in a patient with familial adenomatous polyposis.
    Hu PJ; Knoepp SM; Wu R; Cho KR
    Genes Chromosomes Cancer; 2012 Mar; 51(3):283-9. PubMed ID: 22120905
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Analysis of somatic APC mutations in rare extracolonic tumors of patients with familial adenomatous polyposis coli.
    Bläker H; Sutter C; Kadmon M; Otto HF; Von Knebel-Doeberitz M; Gebert J; Helmke BM
    Genes Chromosomes Cancer; 2004 Oct; 41(2):93-8. PubMed ID: 15287021
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Biallelic APC inactivation was responsible for functional adrenocortical adenoma in familial adenomatous polyposis with novel germline mutation of the APC gene: report of a case.
    Hosogi H; Nagayama S; Kanamoto N; Yoshizawa A; Suzuki T; Nakao K; Sakai Y
    Jpn J Clin Oncol; 2009 Dec; 39(12):837-46. PubMed ID: 19684041
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Wnt/beta-catenin and 3',5'-cyclic adenosine 5'-monophosphate/protein kinase A signaling pathways alterations and somatic beta-catenin gene mutations in the progression of adrenocortical tumors.
    Gaujoux S; Tissier F; Groussin L; Libé R; Ragazzon B; Launay P; Audebourg A; Dousset B; Bertagna X; Bertherat J
    J Clin Endocrinol Metab; 2008 Oct; 93(10):4135-40. PubMed ID: 18647815
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Distinctive molecular genetic alterations in sporadic and familial adenomatous polyposis-associated pancreatoblastomas : frequent alterations in the APC/beta-catenin pathway and chromosome 11p.
    Abraham SC; Wu TT; Klimstra DS; Finn LS; Lee JH; Yeo CJ; Cameron JL; Hruban RH
    Am J Pathol; 2001 Nov; 159(5):1619-27. PubMed ID: 11696422
    [TBL] [Abstract][Full Text] [Related]  

  • 7. [Familial adenomatous polyposis syndrome (FAP): pathogenesis and molecular mechanisms].
    Friedrich A; Kullmann F
    Med Klin (Munich); 2003 Dec; 98(12):776-82. PubMed ID: 14685680
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutations of beta-catenin in adrenocortical tumors: activation of the Wnt signaling pathway is a frequent event in both benign and malignant adrenocortical tumors.
    Tissier F; Cavard C; Groussin L; Perlemoine K; Fumey G; Hagneré AM; René-Corail F; Jullian E; Gicquel C; Bertagna X; Vacher-Lavenu MC; Perret C; Bertherat J
    Cancer Res; 2005 Sep; 65(17):7622-7. PubMed ID: 16140927
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Somatic mutations in familial adenomatous polyps. Nuclear translocation of beta-catenin requires more than biallelic APC inactivation.
    Bläker H; Scholten M; Sutter C; Otto HF; Penzel R
    Am J Clin Pathol; 2003 Sep; 120(3):418-23. PubMed ID: 14502807
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sporadic fundic gland polyps with epithelial dysplasia : evidence for preferential targeting for mutations in the adenomatous polyposis coli gene.
    Abraham SC; Park SJ; Mugartegui L; Hamilton SR; Wu TT
    Am J Pathol; 2002 Nov; 161(5):1735-42. PubMed ID: 12414520
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A beta-catenin mutation in a sporadic colorectal tumor of the RER phenotype and absence of beta-catenin germline mutations in FAP patients.
    Müller O; Nimmrich I; Finke U; Friedl W; Hoffmann I
    Genes Chromosomes Cancer; 1998 May; 22(1):37-41. PubMed ID: 9591632
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutation analysis of the adenomatous polyposis coli (APC) gene in northwest Spanish patients with familial adenomatous polyposis (FAP) and sporadic colorectal cancer.
    Ruiz-Ponte C; Vega A; Carracedo A; Barros F
    Hum Mutat; 2001 Oct; 18(4):355. PubMed ID: 11668620
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nuclear accumulation of beta-catenin without an additional somatic mutation in coding region of the APC gene in hepatoblastoma from a familial adenomatous polyposis patient.
    Inukai T; Furuuchi K; Sugita K; Uno K; Ooi A; Sasaki F; Hamada J; Moriuchi T; Nakazawa S
    Oncol Rep; 2004 Jan; 11(1):121-6. PubMed ID: 14654913
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Promoter hypermethylation leads to decreased APC mRNA expression in familial polyposis and sporadic colorectal tumours, but does not substitute for truncating mutations.
    Segditsas S; Sieber OM; Rowan A; Setien F; Neale K; Phillips RK; Ward R; Esteller M; Tomlinson IP
    Exp Mol Pathol; 2008 Dec; 85(3):201-6. PubMed ID: 18977219
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oncogenic KRAS is not necessary for Wnt signalling activation in APC-associated FAP adenomas.
    Obrador-Hevia A; Chin SF; González S; Rees J; Vilardell F; Greenson JK; Cordero D; Moreno V; Caldas C; Capellá G
    J Pathol; 2010 May; 221(1):57-67. PubMed ID: 20196079
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sporadic fundic gland polyposis: a clinical, histological, and molecular analysis.
    Torbenson M; Lee JH; Cruz-Correa M; Ravich W; Rastgar K; Abraham SC; Wu TT
    Mod Pathol; 2002 Jul; 15(7):718-23. PubMed ID: 12118109
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Fundic gland polyps in familial adenomatous polyposis: neoplasms with frequent somatic adenomatous polyposis coli gene alterations.
    Abraham SC; Nobukawa B; Giardiello FM; Hamilton SR; Wu TT
    Am J Pathol; 2000 Sep; 157(3):747-54. PubMed ID: 10980114
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of Familial Adenomatous Polyposis carriers among children with desmoid tumours.
    Kattentidt Mouravieva AA; Geurts-Giele IR; de Krijger RR; van Noesel MM; van de Ven CP; van den Ouweland AM; Kromosoeto JN; Dinjens WN; Dubbink HJ; Smits R; Wagner A
    Eur J Cancer; 2012 Aug; 48(12):1867-74. PubMed ID: 22305464
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CTNNB1 genotyping and APC screening in pediatric desmoid tumors: a proposed algorithm.
    Wang WL; Nero C; Pappo A; Lev D; Lazar AJ; López-Terrada D
    Pediatr Dev Pathol; 2012; 15(5):361-7. PubMed ID: 22372443
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Contribution of the 15 amino acid repeats of truncated APC to beta-catenin degradation and selection of APC mutations in colorectal tumours from FAP patients.
    Kohler EM; Brauburger K; Behrens J; Schneikert J
    Oncogene; 2010 Mar; 29(11):1663-71. PubMed ID: 19966865
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 47.