220 related articles for article (PubMed ID: 20978346)
1. Loss of Nix in Pdx1-deficient mice prevents apoptotic and necrotic β cell death and diabetes.
Fujimoto K; Ford EL; Tran H; Wice BM; Crosby SD; Dorn GW; Polonsky KS
J Clin Invest; 2010 Nov; 120(11):4031-9. PubMed ID: 20978346
[TBL] [Abstract][Full Text] [Related]
2. Role of BH3-only molecules Bim and Puma in β-cell death in Pdx1 deficiency.
Ren D; Sun J; Wang C; Ye H; Mao L; Cheng EH; Bell GI; Polonsky KS
Diabetes; 2014 Aug; 63(8):2744-50. PubMed ID: 24658302
[TBL] [Abstract][Full Text] [Related]
3. Targeting cyclophilin D and the mitochondrial permeability transition enhances beta-cell survival and prevents diabetes in Pdx1 deficiency.
Fujimoto K; Chen Y; Polonsky KS; Dorn GW
Proc Natl Acad Sci U S A; 2010 Jun; 107(22):10214-9. PubMed ID: 20479245
[TBL] [Abstract][Full Text] [Related]
4. Critical role for the Tsc1-mTORC1 pathway in β-cell mass in Pdx1-deficient mice.
Sun J; Mao L; Yang H; Ren D
J Endocrinol; 2018 Aug; 238(2):151-163. PubMed ID: 29875165
[TBL] [Abstract][Full Text] [Related]
5. Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress.
Sachdeva MM; Claiborn KC; Khoo C; Yang J; Groff DN; Mirmira RG; Stoffers DA
Proc Natl Acad Sci U S A; 2009 Nov; 106(45):19090-5. PubMed ID: 19855005
[TBL] [Abstract][Full Text] [Related]
6. Pancreatic β-Cell Death due to Pdx-1 Deficiency Requires Multi-BH Domain Protein Bax but Not Bak.
Sun J; Mao LQ; Polonsky KS; Ren DC
J Biol Chem; 2016 Jun; 291(26):13529-34. PubMed ID: 27137932
[TBL] [Abstract][Full Text] [Related]
7. A PDX1-ATF transcriptional complex governs β cell survival during stress.
Juliana CA; Yang J; Cannon CE; Good AL; Haemmerle MW; Stoffers DA
Mol Metab; 2018 Nov; 17():39-48. PubMed ID: 30174228
[TBL] [Abstract][Full Text] [Related]
8. Genome-wide analysis of PDX1 target genes in human pancreatic progenitors.
Wang X; Sterr M; Burtscher I; Chen S; Hieronimus A; Machicao F; Staiger H; Häring HU; Lederer G; Meitinger T; Cernilogar FM; Schotta G; Irmler M; Beckers J; Hrabě de Angelis M; Ray M; Wright CVE; Bakhti M; Lickert H
Mol Metab; 2018 Mar; 9():57-68. PubMed ID: 29396371
[TBL] [Abstract][Full Text] [Related]
9. Autophagy regulates pancreatic beta cell death in response to Pdx1 deficiency and nutrient deprivation.
Fujimoto K; Hanson PT; Tran H; Ford EL; Han Z; Johnson JD; Schmidt RE; Green KG; Wice BM; Polonsky KS
J Biol Chem; 2009 Oct; 284(40):27664-73. PubMed ID: 19654319
[TBL] [Abstract][Full Text] [Related]
10. Coxsackievirus B Type 4 Infection in β Cells Downregulates the Chaperone Prefoldin URI to Induce a MODY4-like Diabetes via
Bernard H; Teijeiro A; Chaves-Pérez A; Perna C; Satish B; Novials A; Wang JP; Djouder N
Cell Rep Med; 2020 Oct; 1(7):100125. PubMed ID: 33205075
[TBL] [Abstract][Full Text] [Related]
11. Dracorhodin perchlorate protects pancreatic β-cells against glucotoxicity- or lipotoxicity-induced dysfunction and apoptosis in vitro and in vivo.
Liu L; Liang C; Mei P; Zhu H; Hou M; Yu C; Song Z; Bao Y; Huang Y; Yi J; Wang S; Wu Y; Zheng L; Sun Y; Wang G; Huo M; Yang S; Sun L; Li Y
FEBS J; 2019 Sep; 286(18):3718-3736. PubMed ID: 31349381
[TBL] [Abstract][Full Text] [Related]
12. Suppression of free fatty acid receptor 1 expression in pancreatic β-cells in obese type 2 diabetic db/db mice: a potential role of pancreatic and duodenal homeobox factor 1.
Kohara K; Obata A; Kimura T; Shimoda M; Moriuchi S; Okauchi S; Hirukawa H; Mune T; Kaku K; Kaneto H
Endocr J; 2019 Jan; 66(1):43-50. PubMed ID: 30333365
[TBL] [Abstract][Full Text] [Related]
13. GPR120 protects lipotoxicity-induced pancreatic β-cell dysfunction through regulation of PDX1 expression and inhibition of islet inflammation.
Wang Y; Xie T; Zhang D; Leung PS
Clin Sci (Lond); 2019 Jan; 133(1):101-116. PubMed ID: 30523046
[TBL] [Abstract][Full Text] [Related]
14. Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial-mesenchymal transition in diabetes.
de Jesus DS; Mak TCS; Wang YF; von Ohlen Y; Bai Y; Kane E; Chabosseau P; Chahrour CM; Distaso W; Salem V; Tomas A; Stoffel M; Rutter GA; Latreille M
Mol Metab; 2021 Nov; 53():101248. PubMed ID: 33989778
[TBL] [Abstract][Full Text] [Related]
15. Pancreatic and duodenal homeobox 1 (PDX1) phosphorylation at serine-269 is HIPK2-dependent and affects PDX1 subnuclear localization.
An R; da Silva Xavier G; Semplici F; Vakhshouri S; Hao HX; Rutter J; Pagano MA; Meggio F; Pinna LA; Rutter GA
Biochem Biophys Res Commun; 2010 Aug; 399(2):155-61. PubMed ID: 20637728
[TBL] [Abstract][Full Text] [Related]
16. TAZ promotes PDX1-mediated insulinogenesis.
Jeong MG; Kim HK; Lee G; Won HY; Yoon DH; Hwang ES
Cell Mol Life Sci; 2022 Mar; 79(3):186. PubMed ID: 35279781
[TBL] [Abstract][Full Text] [Related]
17. Hypericin maintians PDX1 expression via the Erk pathway and protects islet β-cells against glucotoxicity and lipotoxicity.
Liang C; Hao F; Yao X; Qiu Y; Liu L; Wang S; Yu C; Song Z; Bao Y; Yi J; Huang Y; Wu Y; Zheng L; Sun Y; Wang G; Yang X; Yang S; Sun L; Li Y
Int J Biol Sci; 2019; 15(7):1472-1487. PubMed ID: 31337977
[TBL] [Abstract][Full Text] [Related]
18. Negative regulation of c-Myc transcription by pancreas duodenum homeobox-1.
Chen L; Yan HX; Chen J; Yang W; Liu Q; Zhai B; Cao HF; Liu SQ; Wu MC; Wang HY
Endocrinology; 2007 May; 148(5):2168-80. PubMed ID: 17317781
[TBL] [Abstract][Full Text] [Related]
19. Transcriptional activity of the islet β cell factor Pdx1 is augmented by lysine methylation catalyzed by the methyltransferase Set7/9.
Maganti AV; Maier B; Tersey SA; Sampley ML; Mosley AL; Özcan S; Pachaiyappan B; Woster PM; Hunter CS; Stein R; Mirmira RG
J Biol Chem; 2015 Apr; 290(15):9812-22. PubMed ID: 25713082
[TBL] [Abstract][Full Text] [Related]
20. Elevated β-cell stress levels promote severe diabetes development in mice with MODY4.
Trojanowski BM; Salem HH; Neubauer H; Simon E; Wagner M; Dorajoo R; Boehm BO; Labriola L; Wirth T; Baumann B
J Endocrinol; 2020 Feb; 244(2):323-337. PubMed ID: 31682591
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
