330 related articles for article (PubMed ID: 20978925)
1. Novel histone deacetylase inhibitor CG200745 induces clonogenic cell death by modulating acetylation of p53 in cancer cells.
Oh ET; Park MT; Choi BH; Ro S; Choi EK; Jeong SY; Park HJ
Invest New Drugs; 2012 Apr; 30(2):435-42. PubMed ID: 20978925
[TBL] [Abstract][Full Text] [Related]
2. Acetylation of p53 at lysine 373/382 by the histone deacetylase inhibitor depsipeptide induces expression of p21(Waf1/Cip1).
Zhao Y; Lu S; Wu L; Chai G; Wang H; Chen Y; Sun J; Yu Y; Zhou W; Zheng Q; Wu M; Otterson GA; Zhu WG
Mol Cell Biol; 2006 Apr; 26(7):2782-90. PubMed ID: 16537920
[TBL] [Abstract][Full Text] [Related]
3. A novel histone deacetylase inhibitor, CG200745, potentiates anticancer effect of docetaxel in prostate cancer via decreasing Mcl-1 and Bcl-XL.
Hwang JJ; Kim YS; Kim T; Kim MJ; Jeong IG; Lee JH; Choi J; Jang S; Ro S; Kim CS
Invest New Drugs; 2012 Aug; 30(4):1434-42. PubMed ID: 21773733
[TBL] [Abstract][Full Text] [Related]
4. Inhibitors of histone deacetylase (HDAC) restore the p53 pathway in neuroblastoma cells.
Condorelli F; Gnemmi I; Vallario A; Genazzani AA; Canonico PL
Br J Pharmacol; 2008 Feb; 153(4):657-68. PubMed ID: 18059320
[TBL] [Abstract][Full Text] [Related]
5. Trichostatin A causes p53 to switch oxidative-damaged colorectal cancer cells from cell cycle arrest into apoptosis.
Habold C; Poehlmann A; Bajbouj K; Hartig R; Korkmaz KS; Roessner A; Schneider-Stock R
J Cell Mol Med; 2008 Apr; 12(2):607-21. PubMed ID: 18419600
[TBL] [Abstract][Full Text] [Related]
6. Green tea polyphenols causes cell cycle arrest and apoptosis in prostate cancer cells by suppressing class I histone deacetylases.
Thakur VS; Gupta K; Gupta S
Carcinogenesis; 2012 Feb; 33(2):377-84. PubMed ID: 22114073
[TBL] [Abstract][Full Text] [Related]
7. Histone deacetylase inhibitor induces cell apoptosis and cycle arrest in lung cancer cells via mitochondrial injury and p53 up-acetylation.
Bao L; Diao H; Dong N; Su X; Wang B; Mo Q; Yu H; Wang X; Chen C
Cell Biol Toxicol; 2016 Dec; 32(6):469-482. PubMed ID: 27423454
[TBL] [Abstract][Full Text] [Related]
8. Green tea polyphenols increase p53 transcriptional activity and acetylation by suppressing class I histone deacetylases.
Thakur VS; Gupta K; Gupta S
Int J Oncol; 2012 Jul; 41(1):353-61. PubMed ID: 22552582
[TBL] [Abstract][Full Text] [Related]
9. Modulation of the cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by Zac1 through the antagonistic regulators p53 and histone deacetylase 1 in HeLa Cells.
Liu PY; Chan JY; Lin HC; Wang SL; Liu ST; Ho CL; Chang LC; Huang SM
Mol Cancer Res; 2008 Jul; 6(7):1204-14. PubMed ID: 18644983
[TBL] [Abstract][Full Text] [Related]
10. Induction of PIG3 and NOXA through acetylation of p53 at 320 and 373 lysine residues as a mechanism for apoptotic cell death by histone deacetylase inhibitors.
Terui T; Murakami K; Takimoto R; Takahashi M; Takada K; Murakami T; Minami S; Matsunaga T; Takayama T; Kato J; Niitsu Y
Cancer Res; 2003 Dec; 63(24):8948-54. PubMed ID: 14695212
[TBL] [Abstract][Full Text] [Related]
11. First-in-human study of the toxicity, pharmacokinetics, and pharmacodynamics of CG200745, a pan-HDAC inhibitor, in patients with refractory solid malignancies.
Kim KP; Park SJ; Kim JE; Hong YS; Lee JL; Bae KS; Cha H; Kwon SK; Ro S; Cho J; Kim TW
Invest New Drugs; 2015 Oct; 33(5):1048-57. PubMed ID: 26076682
[TBL] [Abstract][Full Text] [Related]
12. Histone deacetylase inhibitors, valproic acid and trichostatin-A induce apoptosis and affect acetylation status of p53 in ERG-positive prostate cancer cells.
Fortson WS; Kayarthodi S; Fujimura Y; Xu H; Matthews R; Grizzle WE; Rao VN; Bhat GK; Reddy ES
Int J Oncol; 2011 Jul; 39(1):111-9. PubMed ID: 21519790
[TBL] [Abstract][Full Text] [Related]
13. Histone deacetylase inhibitors enhance the anticancer activity of nutlin-3 and induce p53 hyperacetylation and downregulation of MDM2 and MDM4 gene expression.
Palani CD; Beck JF; Sonnemann J
Invest New Drugs; 2012 Feb; 30(1):25-36. PubMed ID: 20680659
[TBL] [Abstract][Full Text] [Related]
14. Site-specific acetylation of p53 directs selective transcription complex assembly.
Roy S; Tenniswood M
J Biol Chem; 2007 Feb; 282(7):4765-4771. PubMed ID: 17121856
[TBL] [Abstract][Full Text] [Related]
15. A novel class I histone deacetylase inhibitor, I-7ab, induces apoptosis and arrests cell cycle progression in human colorectal cancer cells.
Yang L; Liang Q; Shen K; Ma L; An N; Deng W; Fei Z; Liu J
Biomed Pharmacother; 2015 Apr; 71():70-8. PubMed ID: 25960218
[TBL] [Abstract][Full Text] [Related]
16. Histone deacetylase inhibitors: signalling towards p21cip1/waf1.
Ocker M; Schneider-Stock R
Int J Biochem Cell Biol; 2007; 39(7-8):1367-74. PubMed ID: 17412634
[TBL] [Abstract][Full Text] [Related]
17. Epigenetic modulation with HDAC inhibitor CG200745 induces anti-proliferation in non-small cell lung cancer cells.
Chun SM; Lee JY; Choi J; Lee JH; Hwang JJ; Kim CS; Suh YA; Jang SJ
PLoS One; 2015; 10(3):e0119379. PubMed ID: 25781604
[TBL] [Abstract][Full Text] [Related]
18. [Histone deacetylase inhibitors cause the TP53-dependent induction of p21/Waf1 in tumor cells carrying mutations in TP53].
Kovalev RA; Shtam TA; Karelov DV; Burdakov VS; Volnitskiy AV; Makarov EM; Filatov MV
Tsitologiia; 2015; 57(3):204-11. PubMed ID: 26021170
[TBL] [Abstract][Full Text] [Related]
19. Incompatible effects of p53 and HDAC inhibition on p21 expression and cell cycle progression.
Sachweh MC; Drummond CJ; Higgins M; Campbell J; Laín S
Cell Death Dis; 2013 Mar; 4(3):e533. PubMed ID: 23470540
[TBL] [Abstract][Full Text] [Related]
20. P53-dependent antiproliferative and pro-apoptotic effects of trichostatin A (TSA) in glioblastoma cells.
Bajbouj K; Mawrin C; Hartig R; Schulze-Luehrmann J; Wilisch-Neumann A; Roessner A; Schneider-Stock R
J Neurooncol; 2012 May; 107(3):503-16. PubMed ID: 22270849
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
