325 related articles for article (PubMed ID: 20981526)
1. Design of screening collections for successful fragment-based lead discovery.
Na J; Hu Q
Methods Mol Biol; 2011; 685():219-40. PubMed ID: 20981526
[TBL] [Abstract][Full Text] [Related]
2. Molecular complexity and fragment-based drug discovery: ten years on.
Leach AR; Hann MM
Curr Opin Chem Biol; 2011 Aug; 15(4):489-96. PubMed ID: 21665521
[TBL] [Abstract][Full Text] [Related]
3. Fragment-based drug design.
Feyfant E; Cross JB; Paris K; Tsao DH
Methods Mol Biol; 2011; 685():241-52. PubMed ID: 20981527
[TBL] [Abstract][Full Text] [Related]
4. New directions in library design and analysis.
Gillet VJ
Curr Opin Chem Biol; 2008 Jun; 12(3):372-8. PubMed ID: 18331851
[TBL] [Abstract][Full Text] [Related]
5. Molecular library design using multi-objective optimization methods.
Nicolaou CA; Kannas CC
Methods Mol Biol; 2011; 685():53-69. PubMed ID: 20981518
[TBL] [Abstract][Full Text] [Related]
6. Structure-directed combinatorial library design.
Zhou JZ
Curr Opin Chem Biol; 2008 Jun; 12(3):379-85. PubMed ID: 18328830
[TBL] [Abstract][Full Text] [Related]
7. Adaptive combinatorial design of focused compound libraries.
Schneider G; Schüller A
Methods Mol Biol; 2009; 572():135-47. PubMed ID: 20694689
[TBL] [Abstract][Full Text] [Related]
8. Advancing fragment binders to lead-like compounds using ligand and protein-based NMR spectroscopy.
Maurer T
Methods Enzymol; 2011; 493():469-85. PubMed ID: 21371602
[TBL] [Abstract][Full Text] [Related]
9. Application of QSAR and shape pharmacophore modeling approaches for targeted chemical library design.
Ebalunode JO; Zheng W; Tropsha A
Methods Mol Biol; 2011; 685():111-33. PubMed ID: 20981521
[TBL] [Abstract][Full Text] [Related]
10. Effective progression of nuclear magnetic resonance-detected fragment hits.
Eaton HL; Wyss DF
Methods Enzymol; 2011; 493():447-68. PubMed ID: 21371601
[TBL] [Abstract][Full Text] [Related]
11. Target immobilization as a strategy for NMR-based fragment screening: comparison of TINS, STD, and SPR for fragment hit identification.
Kobayashi M; Retra K; Figaroa F; Hollander JG; Ab E; Heetebrij RJ; Irth H; Siegal G
J Biomol Screen; 2010 Sep; 15(8):978-89. PubMed ID: 20817886
[TBL] [Abstract][Full Text] [Related]
12. Efficiency of hit generation and structural characterization in fragment-based ligand discovery.
Larsson A; Jansson A; Åberg A; Nordlund P
Curr Opin Chem Biol; 2011 Aug; 15(4):482-8. PubMed ID: 21724447
[TBL] [Abstract][Full Text] [Related]
13. Practical aspects of NMR-based fragment screening.
Lepre CA
Methods Enzymol; 2011; 493():219-39. PubMed ID: 21371593
[TBL] [Abstract][Full Text] [Related]
14. Fragment-based activity space: smaller is better.
Hesterkamp T; Whittaker M
Curr Opin Chem Biol; 2008 Jun; 12(3):260-8. PubMed ID: 18316043
[TBL] [Abstract][Full Text] [Related]
15. Strategies for the use of mixture-based synthetic combinatorial libraries: scaffold ranking, direct testing in vivo, and enhanced deconvolution by computational methods.
Houghten RA; Pinilla C; Giulianotti MA; Appel JR; Dooley CT; Nefzi A; Ostresh JM; Yu Y; Maggiora GM; Medina-Franco JL; Brunner D; Schneider J
J Comb Chem; 2008; 10(1):3-19. PubMed ID: 18067268
[No Abstract] [Full Text] [Related]
16. Using computational techniques in fragment-based drug discovery.
Desjarlais RL
Methods Enzymol; 2011; 493():137-55. PubMed ID: 21371590
[TBL] [Abstract][Full Text] [Related]
17. The synergy between combinatorial chemistry and high-throughput screening.
Diller DJ
Curr Opin Drug Discov Devel; 2008 May; 11(3):346-55. PubMed ID: 18428088
[TBL] [Abstract][Full Text] [Related]
18. Recent trends and observations in the design of high-quality screening collections.
Renner S; Popov M; Schuffenhauer A; Roth HJ; Breitenstein W; Marzinzik A; Lewis I; Krastel P; Nigsch F; Jenkins J; Jacoby E
Future Med Chem; 2011 Apr; 3(6):751-66. PubMed ID: 21554080
[TBL] [Abstract][Full Text] [Related]
19. Combinatorial library design from reagent pharmacophore fingerprints.
Chen H; Engkvist O; Blomberg N
Methods Mol Biol; 2011; 685():135-52. PubMed ID: 20981522
[TBL] [Abstract][Full Text] [Related]
20. Virtual screening of compound libraries.
Cerqueira NM; Sousa SF; Fernandes PA; Ramos MJ
Methods Mol Biol; 2009; 572():57-70. PubMed ID: 20694685
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
