BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

676 related articles for article (PubMed ID: 20981528)

  • 1. LEAP into the Pfizer Global Virtual Library (PGVL) space: creation of readily synthesizable design ideas automatically.
    Hu Q; Peng Z; Kostrowicki J; Kuki A
    Methods Mol Biol; 2011; 685():253-76. PubMed ID: 20981528
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PGVL Hub: An integrated desktop tool for medicinal chemists to streamline design and synthesis of chemical libraries and singleton compounds.
    Peng Z; Yang B; Mattaparti S; Shulok T; Thacher T; Kong J; Kostrowicki J; Hu Q; Na J; Zhou JZ; Klatte D; Chao B; Ito S; Clark J; Sciammetta N; Coner B; Waller C; Kuki A
    Methods Mol Biol; 2011; 685():295-320. PubMed ID: 20981530
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure-based and property-compliant library design of 11β-HSD1 adamantyl amide inhibitors.
    Paderes GD; Dress K; Huang B; Elleraas J; Rejto PA; Pauly T
    Methods Mol Biol; 2011; 685():191-215. PubMed ID: 20981525
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Searching chemical space with the Bayesian Idea Generator.
    van Hoorn WP; Bell AS
    J Chem Inf Model; 2009 Oct; 49(10):2211-20. PubMed ID: 19788263
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Chemoinformatics and library design.
    Zhou JZ
    Methods Mol Biol; 2011; 685():27-52. PubMed ID: 20981517
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Charting, navigating, and populating natural product chemical space for drug discovery.
    Lachance H; Wetzel S; Kumar K; Waldmann H
    J Med Chem; 2012 Jul; 55(13):5989-6001. PubMed ID: 22537178
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Combinatorial library design from reagent pharmacophore fingerprints.
    Chen H; Engkvist O; Blomberg N
    Methods Mol Biol; 2011; 685():135-52. PubMed ID: 20981522
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular library design using multi-objective optimization methods.
    Nicolaou CA; Kannas CC
    Methods Mol Biol; 2011; 685():53-69. PubMed ID: 20981518
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Docking methods for structure-based library design.
    Cavasotto CN; Phatak SS
    Methods Mol Biol; 2011; 685():155-74. PubMed ID: 20981523
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Automatic tailoring and transplanting: a practical method that makes virtual screening more useful.
    Li Y; Zhao Y; Liu Z; Wang R
    J Chem Inf Model; 2011 Jun; 51(6):1474-91. PubMed ID: 21520918
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Unconventional 2D shape similarity method affords comparable enrichment as a 3D shape method in virtual screening experiments.
    Ebalunode JO; Zheng W
    J Chem Inf Model; 2009 Jun; 49(6):1313-20. PubMed ID: 19480404
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ultrafast shape recognition: evaluating a new ligand-based virtual screening technology.
    Ballester PJ; Finn PW; Richards WG
    J Mol Graph Model; 2009 Apr; 27(7):836-45. PubMed ID: 19188082
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pfizer Global Virtual Library (PGVL): a chemistry design tool powered by experimentally validated parallel synthesis information.
    Hu Q; Peng Z; Sutton SC; Na J; Kostrowicki J; Yang B; Thacher T; Kong X; Mattaparti S; Zhou JZ; Gonzalez J; Ramirez-Weinhouse M; Kuki A
    ACS Comb Sci; 2012 Nov; 14(11):579-89. PubMed ID: 23020747
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design of targeted libraries against the human Chk1 kinase using PGVL Hub.
    Peng Z; Hu Q
    Methods Mol Biol; 2011; 685():321-36. PubMed ID: 20981531
    [TBL] [Abstract][Full Text] [Related]  

  • 15. FSees: Customized Enumeration of Chemical Subspaces with Limited Main Memory Consumption.
    Lauck F; Rarey M
    J Chem Inf Model; 2016 Sep; 56(9):1641-53. PubMed ID: 27617881
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Application of Free-Wilson selectivity analysis for combinatorial library design.
    Sciabola S; Stanton RV; Johnson TL; Xi H
    Methods Mol Biol; 2011; 685():91-109. PubMed ID: 20981520
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Chemical-text hybrid search engines.
    Zhou Y; Zhou B; Jiang S; King FJ
    J Chem Inf Model; 2010 Jan; 50(1):47-54. PubMed ID: 20047295
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A scalable approach to combinatorial library design.
    Sharma P; Salapaka S; Beck C
    Methods Mol Biol; 2011; 685():71-89. PubMed ID: 20981519
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Similarity searching and scaffold hopping in synthetically accessible combinatorial chemistry spaces.
    Boehm M; Wu TY; Claussen H; Lemmen C
    J Med Chem; 2008 Apr; 51(8):2468-80. PubMed ID: 18380426
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SymDex: increasing the efficiency of chemical fingerprint similarity searches for comparing large chemical libraries by using query set indexing.
    Tai D; Fang J
    J Chem Inf Model; 2012 Aug; 52(8):1926-35. PubMed ID: 22849555
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 34.