BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 21030983)

  • 1. Pre-B-cell leukemias in Btk/Slp65-deficient mice arise independently of ongoing V(D)J recombination activity.
    Ta VB; de Haan AB; de Bruijn MJ; Dingjan GM; Hendriks RW
    Leukemia; 2011 Jan; 25(1):48-56. PubMed ID: 21030983
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Highly restricted usage of Ig H chain VH14 family gene segments in Slp65-deficient pre-B cell leukemia in mice.
    Ta VB; de Bruijn MJ; Matheson L; Zoller M; Bach MP; Wardemann H; Jumaa H; Corcoran A; Hendriks RW
    J Immunol; 2012 Nov; 189(10):4842-51. PubMed ID: 23066158
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Malignant transformation of Slp65-deficient pre-B cells involves disruption of the Arf-Mdm2-p53 tumor suppressor pathway.
    Ta VB; de Bruijn MJ; ter Brugge PJ; van Hamburg JP; Diepstraten HJ; van Loo PF; Kersseboom R; Hendriks RW
    Blood; 2010 Feb; 115(7):1385-93. PubMed ID: 20008789
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The BCR-ABL1 kinase bypasses selection for the expression of a pre-B cell receptor in pre-B acute lymphoblastic leukemia cells.
    Klein F; Feldhahn N; Harder L; Wang H; Wartenberg M; Hofmann WK; Wernet P; Siebert R; Müschen M
    J Exp Med; 2004 Mar; 199(5):673-85. PubMed ID: 14993251
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SLP65 deficiency results in perpetual V(D)J recombinase activity in pre-B-lymphoblastic leukemia and B-cell lymphoma cells.
    Sprangers M; Feldhahn N; Liedtke S; Jumaa H; Siebert R; Müschen M
    Oncogene; 2006 Aug; 25(37):5180-6. PubMed ID: 16636677
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bruton's tyrosine kinase cooperates with the B cell linker protein SLP-65 as a tumor suppressor in Pre-B cells.
    Kersseboom R; Middendorp S; Dingjan GM; Dahlenborg K; Reth M; Jumaa H; Hendriks RW
    J Exp Med; 2003 Jul; 198(1):91-8. PubMed ID: 12835482
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Bruton's tyrosine kinase and SLP-65 regulate pre-B cell differentiation and the induction of Ig light chain gene rearrangement.
    Kersseboom R; Ta VB; Zijlstra AJ; Middendorp S; Jumaa H; van Loo PF; Hendriks RW
    J Immunol; 2006 Apr; 176(8):4543-52. PubMed ID: 16585544
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A truncated heavy chain protein relieves the requirement for surrogate light chains in early B cell development.
    Shaffer AL; Schlissel MS
    J Immunol; 1997 Aug; 159(3):1265-75. PubMed ID: 9233622
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Surface mu heavy chain signals down-regulation of the V(D)J-recombinase machinery in the absence of surrogate light chain components.
    Galler GR; Mundt C; Parker M; Pelanda R; Mårtensson IL; Winkler TH
    J Exp Med; 2004 Jun; 199(11):1523-32. PubMed ID: 15173209
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Deficiency of Bruton's tyrosine kinase in B cell precursor leukemia cells.
    Feldhahn N; Río P; Soh BN; Liedtke S; Sprangers M; Klein F; Wernet P; Jumaa H; Hofmann WK; Hanenberg H; Rowley JD; Müschen M
    Proc Natl Acad Sci U S A; 2005 Sep; 102(37):13266-71. PubMed ID: 16141323
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Bruton's tyrosine kinase regulates the activation of gene rearrangements at the lambda light chain locus in precursor B cells in the mouse.
    Dingjan GM; Middendorp S; Dahlenborg K; Maas A; Grosveld F; Hendriks RW
    J Exp Med; 2001 May; 193(10):1169-78. PubMed ID: 11369788
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Involvement of SLP-65 and Btk in tumor suppression and malignant transformation of pre-B cells.
    Hendriks RW; Kersseboom R
    Semin Immunol; 2006 Feb; 18(1):67-76. PubMed ID: 16300960
    [TBL] [Abstract][Full Text] [Related]  

  • 13. B cell defects in SLP65/BLNK-deficient mice can be partially corrected by the absence of CD22, an inhibitory coreceptor for BCR signaling.
    Gerlach J; Ghosh S; Jumaa H; Reth M; Wienands J; Chan AC; Nitschke L
    Eur J Immunol; 2003 Dec; 33(12):3418-26. PubMed ID: 14635051
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The SRC family kinase LYN redirects B cell receptor signaling in human SLP65-deficient B cell lymphoma cells.
    Sprangers M; Feldhahn N; Herzog S; Hansmann ML; Reppel M; Hescheler J; Jumaa H; Siebert R; Müschen M
    Oncogene; 2006 Aug; 25(36):5056-62. PubMed ID: 16568084
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bruton's tyrosine kinase is not essential for Bcr-Abl-mediated transformation of lymphoid or myeloid cells.
    MacPartlin M; Smith AM; Druker BJ; Honigberg LA; Deininger MW
    Leukemia; 2008 Jul; 22(7):1354-60. PubMed ID: 18548107
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Surrogate-light-chain silencing is not critical for the limitation of pre-B cell expansion but is for the termination of constitutive signaling.
    van Loo PF; Dingjan GM; Maas A; Hendriks RW
    Immunity; 2007 Sep; 27(3):468-80. PubMed ID: 17869135
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cellular maturation defects in Bruton's tyrosine kinase-deficient immature B cells are amplified by premature B cell receptor expression and reduced by receptor editing.
    Middendorp S; Hendriks RW
    J Immunol; 2004 Feb; 172(3):1371-9. PubMed ID: 14734712
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genetic interaction between PARP and DNA-PK in V(D)J recombination and tumorigenesis.
    Morrison C; Smith GC; Stingl L; Jackson SP; Wagner EF; Wang ZQ
    Nat Genet; 1997 Dec; 17(4):479-82. PubMed ID: 9398855
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pre-B cell receptor-mediated selection of pre-B cells synthesizing functional mu heavy chains.
    Kline GH; Hartwell L; Beck-Engeser GB; Keyna U; Zaharevitz S; Klinman NR; Jäck HM
    J Immunol; 1998 Aug; 161(4):1608-18. PubMed ID: 9712022
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The absence of SLP65 and Btk blocks B cell development at the preB cell receptor-positive stage.
    Jumaa H; Mitterer M; Reth M; Nielsen PJ
    Eur J Immunol; 2001 Jul; 31(7):2164-9. PubMed ID: 11449370
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.