185 related articles for article (PubMed ID: 21035456)
1. Inhibition of nonsense-mediated mRNA decay by antisense morpholino oligonucleotides restores functional expression of hERG nonsense and frameshift mutations in long-QT syndrome.
Gong Q; Stump MR; Zhou Z
J Mol Cell Cardiol; 2011 Jan; 50(1):223-9. PubMed ID: 21035456
[TBL] [Abstract][Full Text] [Related]
2. Position of premature termination codons determines susceptibility of hERG mutations to nonsense-mediated mRNA decay in long QT syndrome.
Gong Q; Stump MR; Zhou Z
Gene; 2014 Apr; 539(2):190-7. PubMed ID: 24530480
[TBL] [Abstract][Full Text] [Related]
3. Nonsense-mediated mRNA decay caused by a frameshift mutation in a large kindred of type 2 long QT syndrome.
Zarraga IG; Zhang L; Stump MR; Gong Q; Vincent GM; Zhou Z
Heart Rhythm; 2011 Aug; 8(8):1200-6. PubMed ID: 21419236
[TBL] [Abstract][Full Text] [Related]
4. Nonsense mutations in hERG cause a decrease in mutant mRNA transcripts by nonsense-mediated mRNA decay in human long-QT syndrome.
Gong Q; Zhang L; Vincent GM; Horne BD; Zhou Z
Circulation; 2007 Jul; 116(1):17-24. PubMed ID: 17576861
[TBL] [Abstract][Full Text] [Related]
5. Early LQT2 nonsense mutation generates N-terminally truncated hERG channels with altered gating properties by the reinitiation of translation.
Stump MR; Gong Q; Packer JD; Zhou Z
J Mol Cell Cardiol; 2012 Nov; 53(5):725-33. PubMed ID: 22964610
[TBL] [Abstract][Full Text] [Related]
6. Nonsense-Mediated mRNA Decay of hERG Mutations in Long QT Syndrome.
Gong Q; Zhou Z
Methods Mol Biol; 2018; 1684():37-49. PubMed ID: 29058182
[TBL] [Abstract][Full Text] [Related]
7. Deciphering HERG mutation in long QT syndrome type 2 using antisense oligonucleotide-mediated techniques: Lessons from cystic fibrosis.
Zheng Z; Song Y; Tan X
Heart Rhythm; 2023 Aug; 20(8):1169-1177. PubMed ID: 37121422
[TBL] [Abstract][Full Text] [Related]
8. LQT2 nonsense mutations generate trafficking defective NH2-terminally truncated channels by the reinitiation of translation.
Stump MR; Gong Q; Zhou Z
Am J Physiol Heart Circ Physiol; 2013 Nov; 305(9):H1397-404. PubMed ID: 23997099
[TBL] [Abstract][Full Text] [Related]
9. Recurrent intrauterine fetal loss due to near absence of HERG: clinical and functional characterization of a homozygous nonsense HERG Q1070X mutation.
Bhuiyan ZA; Momenah TS; Gong Q; Amin AS; Ghamdi SA; Carvalho JS; Homfray T; Mannens MM; Zhou Z; Wilde AA
Heart Rhythm; 2008 Apr; 5(4):553-61. PubMed ID: 18362022
[TBL] [Abstract][Full Text] [Related]
10. A novel nonsense mutation Y652X in the S6/pore region of human ether-go-go gene found in a long QT syndrome family.
Sun Y; Zhang P; Li X; Zhang H; Li J; Liu G; Guo J
Scand Cardiovasc J; 2009 Jun; 43(3):181-6. PubMed ID: 19034806
[TBL] [Abstract][Full Text] [Related]
11. Aminoglycoside antibiotics restore functional expression of truncated HERG channels produced by nonsense mutations.
Yao Y; Teng S; Li N; Zhang Y; Boyden PA; Pu J
Heart Rhythm; 2009 Apr; 6(4):553-60. PubMed ID: 19324319
[TBL] [Abstract][Full Text] [Related]
12. A novel deletion-frameshift mutation in the S1 region of HERG gene in a Chinese family with long QT syndrome.
Gao Y; Zhang P; Li XB; Wu CC; Guo JH
Chin Med J (Engl); 2013 Aug; 126(16):3093-6. PubMed ID: 23981618
[TBL] [Abstract][Full Text] [Related]
13. Defective assembly and trafficking of mutant HERG channels with C-terminal truncations in long QT syndrome.
Gong Q; Keeney DR; Robinson JC; Zhou Z
J Mol Cell Cardiol; 2004 Dec; 37(6):1225-33. PubMed ID: 15572053
[TBL] [Abstract][Full Text] [Related]
14. Multiple splicing defects caused by hERG splice site mutation 2592+1G>A associated with long QT syndrome.
Stump MR; Gong Q; Zhou Z
Am J Physiol Heart Circ Physiol; 2011 Jan; 300(1):H312-8. PubMed ID: 21057041
[TBL] [Abstract][Full Text] [Related]
15. Most LQT2 mutations reduce Kv11.1 (hERG) current by a class 2 (trafficking-deficient) mechanism.
Anderson CL; Delisle BP; Anson BD; Kilby JA; Will ML; Tester DJ; Gong Q; Zhou Z; Ackerman MJ; January CT
Circulation; 2006 Jan; 113(3):365-73. PubMed ID: 16432067
[TBL] [Abstract][Full Text] [Related]
16. Upregulation of functional Kv11.1 isoform expression by inhibition of intronic polyadenylation with antisense morpholino oligonucleotides.
Gong Q; Stump MR; Zhou Z
J Mol Cell Cardiol; 2014 Nov; 76():26-32. PubMed ID: 25128783
[TBL] [Abstract][Full Text] [Related]
17. Properties of WT and mutant hERG K(+) channels expressed in neonatal mouse cardiomyocytes.
Lin EC; Holzem KM; Anson BD; Moungey BM; Balijepalli SY; Tester DJ; Ackerman MJ; Delisle BP; Balijepalli RC; January CT
Am J Physiol Heart Circ Physiol; 2010 Jun; 298(6):H1842-9. PubMed ID: 20363883
[TBL] [Abstract][Full Text] [Related]
18. Antisense suppression of the nonsense mediated decay factor Upf3b as a potential treatment for diseases caused by nonsense mutations.
Huang L; Low A; Damle SS; Keenan MM; Kuntz S; Murray SF; Monia BP; Guo S
Genome Biol; 2018 Jan; 19(1):4. PubMed ID: 29334995
[TBL] [Abstract][Full Text] [Related]
19. Novel C-terminus frameshift mutation, 1122fs/147, of HERG in LQT2: additional amino acids generated by frameshift cause accelerated inactivation.
Sasano T; Ueda K; Orikabe M; Hirano Y; Kawano S; Yasunami M; Isobe M; Kimura A; Hiraoka M
J Mol Cell Cardiol; 2004 Dec; 37(6):1205-11. PubMed ID: 15572050
[TBL] [Abstract][Full Text] [Related]
20. HERG mutation predicts short QT based on channel kinetics but causes long QT by heterotetrameric trafficking deficiency.
Paulussen AD; Raes A; Jongbloed RJ; Gilissen RA; Wilde AA; Snyders DJ; Smeets HJ; Aerssens J
Cardiovasc Res; 2005 Aug; 67(3):467-75. PubMed ID: 15958262
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]