BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 21035945)

  • 21. Disulfiram treatment facilitates phosphoinositide 3-kinase inhibition in human breast cancer cells in vitro and in vivo.
    Zhang H; Chen D; Ringler J; Chen W; Cui QC; Ethier SP; Dou QP; Wu G
    Cancer Res; 2010 May; 70(10):3996-4004. PubMed ID: 20424113
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Pyrrolidine dithiocarbamate-induced apoptosis depends on cell type, density, and the presence of Cu(2+) and Zn(2+).
    Erl W; Weber C; Hansson GK
    Am J Physiol Cell Physiol; 2000 Jun; 278(6):C1116-25. PubMed ID: 10837339
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Two clinical drugs deubiquitinase inhibitor auranofin and aldehyde dehydrogenase inhibitor disulfiram trigger synergistic anti-tumor effects in vitro and in vivo.
    Huang H; Liao Y; Liu N; Hua X; Cai J; Yang C; Long H; Zhao C; Chen X; Lan X; Zang D; Wu J; Li X; Shi X; Wang X; Liu J
    Oncotarget; 2016 Jan; 7(3):2796-808. PubMed ID: 26625200
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Copper-binding compounds as proteasome inhibitors and apoptosis inducers in human cancer.
    Daniel KG; Chen D; Yan B; Dou QP
    Front Biosci; 2007 Jan; 12():135-44. PubMed ID: 17127289
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Potent anticancer activity of pyrrolidine dithiocarbamate-copper complex against cisplatin-resistant neuroblastoma cells.
    Zhang H; Wu JS; Peng F
    Anticancer Drugs; 2008 Feb; 19(2):125-32. PubMed ID: 18176108
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Pyrrolidine dithiocarbamate inhibits enterovirus 71 replication by down-regulating ubiquitin-proteasome system.
    Lin L; Qin Y; Wu H; Chen Y; Wu S; Si X; Wang H; Wang T; Zhong X; Zhai X; Tong L; Pan B; Zhang F; Zhong Z; Wang Y; Zhao W
    Virus Res; 2015 Jan; 195():207-16. PubMed ID: 25456405
    [TBL] [Abstract][Full Text] [Related]  

  • 27. S-methyl N,N-diethylthiocarbamate sulfone, a potential metabolite of disulfiram and potent inhibitor of low Km mitochondrial aldehyde dehydrogenase.
    Mays DC; Nelson AN; Fauq AH; Shriver ZH; Veverka KA; Naylor S; Lipsky JJ
    Biochem Pharmacol; 1995 Mar; 49(5):693-700. PubMed ID: 7887984
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Involvement of activating transcription factors JNK, NF-kappaB, and AP-1 in apoptosis induced by pyrrolidine dithiocarbamate/Cu complex.
    Chen SH; Lin JK; Liang YC; Pan MH; Liu SH; Lin-Shiau SY
    Eur J Pharmacol; 2008 Oct; 594(1-3):9-17. PubMed ID: 18671963
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Disulfiram promotes the conversion of carcinogenic cadmium to a proteasome inhibitor with pro-apoptotic activity in human cancer cells.
    Li L; Yang H; Chen D; Cui C; Dou QP
    Toxicol Appl Pharmacol; 2008 Jun; 229(2):206-14. PubMed ID: 18304598
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Disulfiram/copper targets stem cell-like ALDH
    Jin N; Zhu X; Cheng F; Zhang L
    J Cell Biochem; 2018 Aug; 119(8):6882-6893. PubMed ID: 29665144
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Novel 8-hydroxylquinoline analogs induce copper-dependent proteasome inhibition and cell death in human breast cancer cells.
    Milacic V; Jiao P; Zhang B; Yan B; Dou QP
    Int J Oncol; 2009 Dec; 35(6):1481-91. PubMed ID: 19885572
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Inhibition of proteasome activity, nuclear factor-KappaB translocation and cell survival by the antialcoholism drug disulfiram.
    Lövborg H; Oberg F; Rickardson L; Gullbo J; Nygren P; Larsson R
    Int J Cancer; 2006 Mar; 118(6):1577-80. PubMed ID: 16206267
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Disulfiram modulates ROS accumulation and overcomes synergistically cisplatin resistance in breast cancer cell lines.
    Yang Z; Guo F; Albers AE; Sehouli J; Kaufmann AM
    Biomed Pharmacother; 2019 May; 113():108727. PubMed ID: 30870721
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Dithiocarbamate toxicity toward thymocytes involves their copper-catalyzed conversion to thiuram disulfides, which oxidize glutathione in a redox cycle without the release of reactive oxygen species.
    Burkitt MJ; Bishop HS; Milne L; Tsang SY; Provan GJ; Nobel CS; Orrenius S; Slater AF
    Arch Biochem Biophys; 1998 May; 353(1):73-84. PubMed ID: 9578602
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Death signaling pathway induced by pyrrolidine dithiocarbamate-Cu(2+) complex in the cultured rat cortical astrocytes.
    Chen SH; Liu SH; Liang YC; Lin JK; Lin-Shiau SY
    Glia; 2000 Sep; 31(3):249-61. PubMed ID: 10941151
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Inhibition of human erythrocyte and leukocyte aldehyde dehydrogenase activities by diethylthiocarbamic acid methyl ester. An in vivo metabolite of disulfiram.
    Helander A; Johansson B
    Biochem Pharmacol; 1989 Jul; 38(13):2195-8. PubMed ID: 2735956
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Novel biphasic effect of pyrrolidine dithiocarbamate on neuronal cell viability is mediated by the differential regulation of intracellular zinc and copper ion levels, NF-kappaB, and MAP kinases.
    Chung KC; Park JH; Kim CH; Lee HW; Sato N; Uchiyama Y; Ahn YS
    J Neurosci Res; 2000 Jan; 59(1):117-25. PubMed ID: 10658192
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The thiocarbamate disulphide drug, disulfiram induces osteopenia in rats by inhibition of osteoblast function due to suppression of acetaldehyde dehydrogenase activity.
    Mittal M; Khan K; Pal S; Porwal K; China SP; Barbhuyan TK; Baghel KS; Rawat T; Sanyal S; Bhadauria S; Sharma VL; Chattopadhyay N
    Toxicol Sci; 2014 May; 139(1):257-70. PubMed ID: 24496638
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Dithiocarbamate-based coordination compounds as potent proteasome inhibitors in human cancer cells.
    Buac D; Schmitt S; Ventro G; Kona FR; Dou QP
    Mini Rev Med Chem; 2012 Oct; 12(12):1193-201. PubMed ID: 22931591
    [TBL] [Abstract][Full Text] [Related]  

  • 40. In Vivo Anti-Tumor Effects of Citral on 4T1 Breast Cancer Cells via Induction of Apoptosis and Downregulation of Aldehyde Dehydrogenase Activity.
    Nigjeh SE; Yeap SK; Nordin N; Rahman H; Rosli R
    Molecules; 2019 Sep; 24(18):. PubMed ID: 31492037
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.