These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

622 related articles for article (PubMed ID: 21037563)

  • 1. The structural basis for membrane binding and pore formation by lymphocyte perforin.
    Law RH; Lukoyanova N; Voskoboinik I; Caradoc-Davies TT; Baran K; Dunstone MA; D'Angelo ME; Orlova EV; Coulibaly F; Verschoor S; Browne KA; Ciccone A; Kuiper MJ; Bird PI; Trapani JA; Saibil HR; Whisstock JC
    Nature; 2010 Nov; 468(7322):447-51. PubMed ID: 21037563
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cholesterol-dependent cytolysins.
    Gilbert RJ
    Adv Exp Med Biol; 2010; 677():56-66. PubMed ID: 20687480
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Defining the interaction of perforin with calcium and the phospholipid membrane.
    Traore DA; Brennan AJ; Law RH; Dogovski C; Perugini MA; Lukoyanova N; Leung EW; Norton RS; Lopez JA; Browne KA; Yagita H; Lloyd GJ; Ciccone A; Verschoor S; Trapani JA; Whisstock JC; Voskoboinik I
    Biochem J; 2013 Dec; 456(3):323-35. PubMed ID: 24070258
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A common fold mediates vertebrate defense and bacterial attack.
    Rosado CJ; Buckle AM; Law RH; Butcher RE; Kan WT; Bird CH; Ung K; Browne KA; Baran K; Bashtannyk-Puhalovich TA; Faux NG; Wong W; Porter CJ; Pike RN; Ellisdon AM; Pearce MC; Bottomley SP; Emsley J; Smith AI; Rossjohn J; Hartland EL; Voskoboinik I; Trapani JA; Bird PI; Dunstone MA; Whisstock JC
    Science; 2007 Sep; 317(5844):1548-51. PubMed ID: 17717151
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack.
    Lopez JA; Susanto O; Jenkins MR; Lukoyanova N; Sutton VR; Law RH; Johnston A; Bird CH; Bird PI; Whisstock JC; Trapani JA; Saibil HR; Voskoboinik I
    Blood; 2013 Apr; 121(14):2659-68. PubMed ID: 23377437
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Stepwise visualization of membrane pore formation by suilysin, a bacterial cholesterol-dependent cytolysin.
    Leung C; Dudkina NV; Lukoyanova N; Hodel AW; Farabella I; Pandurangan AP; Jahan N; Pires Damaso M; Osmanović D; Reboul CF; Dunstone MA; Andrew PW; Lonnen R; Topf M; Saibil HR; Hoogenboom BW
    Elife; 2014 Dec; 3():e04247. PubMed ID: 25457051
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The perforin pore facilitates the delivery of cationic cargos.
    Stewart SE; Kondos SC; Matthews AY; D'Angelo ME; Dunstone MA; Whisstock JC; Trapani JA; Bird PI
    J Biol Chem; 2014 Mar; 289(13):9172-81. PubMed ID: 24558045
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Stonefish toxin defines an ancient branch of the perforin-like superfamily.
    Ellisdon AM; Reboul CF; Panjikar S; Huynh K; Oellig CA; Winter KL; Dunstone MA; Hodgson WC; Seymour J; Dearden PK; Tweten RK; Whisstock JC; McGowan S
    Proc Natl Acad Sci U S A; 2015 Dec; 112(50):15360-5. PubMed ID: 26627714
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Structural Basis for a Transition State That Regulates Pore Formation in a Bacterial Toxin.
    Wade KR; Lawrence SL; Farrand AJ; Hotze EM; Kuiper MJ; Gorman MA; Christie MP; Panjikar S; Morton CJ; Parker MW; Tweten RK
    mBio; 2019 Apr; 10(2):. PubMed ID: 31015325
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure of C8alpha-MACPF reveals mechanism of membrane attack in complement immune defense.
    Hadders MA; Beringer DX; Gros P
    Science; 2007 Sep; 317(5844):1552-4. PubMed ID: 17872444
    [TBL] [Abstract][Full Text] [Related]  

  • 11. X-ray and Cryo-electron Microscopy Structures of Monalysin Pore-forming Toxin Reveal Multimerization of the Pro-form.
    Leone P; Bebeacua C; Opota O; Kellenberger C; Klaholz B; Orlov I; Cambillau C; Lemaitre B; Roussel A
    J Biol Chem; 2015 May; 290(21):13191-201. PubMed ID: 25847242
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Membrane interactions and cellular effects of MACPF/CDC proteins.
    Cajnko MM; Mikelj M; Turk T; Podobnik M; Anderluh G
    Subcell Biochem; 2014; 80():119-44. PubMed ID: 24798010
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Conformational changes during pore formation by the perforin-related protein pleurotolysin.
    Lukoyanova N; Kondos SC; Farabella I; Law RH; Reboul CF; Caradoc-Davies TT; Spicer BA; Kleifeld O; Traore DA; Ekkel SM; Voskoboinik I; Trapani JA; Hatfaludi T; Oliver K; Hotze EM; Tweten RK; Whisstock JC; Topf M; Saibil HR; Dunstone MA
    PLoS Biol; 2015 Feb; 13(2):e1002049. PubMed ID: 25654333
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Friend or foe: the same fold for attack and defense.
    Lukoyanova N; Saibil HR
    Trends Immunol; 2008 Feb; 29(2):51-3. PubMed ID: 18248850
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells.
    Thiery J; Keefe D; Boulant S; Boucrot E; Walch M; Martinvalet D; Goping IS; Bleackley RC; Kirchhausen T; Lieberman J
    Nat Immunol; 2011 Jun; 12(8):770-7. PubMed ID: 21685908
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An Intermolecular π-Stacking Interaction Drives Conformational Changes Necessary to β-Barrel Formation in a Pore-Forming Toxin.
    Burns JR; Morton CJ; Parker MW; Tweten RK
    mBio; 2019 Jul; 10(4):. PubMed ID: 31266869
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Packing a punch: the mechanism of pore formation by cholesterol dependent cytolysins and membrane attack complex/perforin-like proteins.
    Dunstone MA; Tweten RK
    Curr Opin Struct Biol; 2012 Jun; 22(3):342-9. PubMed ID: 22658510
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pore-forming proteins and their role in cancer and inflammation: Mechanistic insights and plausible druggable targets.
    Sankar J; Arora S; Joshi G; Kumar R
    Chem Biol Interact; 2022 Oct; 366():110127. PubMed ID: 36055376
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Real-time visualization of perforin nanopore assembly.
    Leung C; Hodel AW; Brennan AJ; Lukoyanova N; Tran S; House CM; Kondos SC; Whisstock JC; Dunstone MA; Trapani JA; Voskoboinik I; Saibil HR; Hoogenboom BW
    Nat Nanotechnol; 2017 May; 12(5):467-473. PubMed ID: 28166206
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Membrane cholesterol and sphingomyelin, and ostreolysin A are obligatory for pore-formation by a MACPF/CDC-like pore-forming protein, pleurotolysin B.
    Ota K; Leonardi A; Mikelj M; Skočaj M; Wohlschlager T; Künzler M; Aebi M; Narat M; Križaj I; Anderluh G; Sepčić K; Maček P
    Biochimie; 2013 Oct; 95(10):1855-64. PubMed ID: 23806422
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 32.