These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

379 related articles for article (PubMed ID: 21040903)

  • 1. Friedreich's ataxia induced pluripotent stem cells model intergenerational GAA⋅TTC triplet repeat instability.
    Ku S; Soragni E; Campau E; Thomas EA; Altun G; Laurent LC; Loring JF; Napierala M; Gottesfeld JM
    Cell Stem Cell; 2010 Nov; 7(5):631-7. PubMed ID: 21040903
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Alleviating GAA Repeat Induced Transcriptional Silencing of the Friedreich's Ataxia Gene During Somatic Cell Reprogramming.
    Polak U; Li Y; Butler JS; Napierala M
    Stem Cells Dev; 2016 Dec; 25(23):1788-1800. PubMed ID: 27615158
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of mismatch repair enzymes in GAA·TTC triplet-repeat expansion in Friedreich ataxia induced pluripotent stem cells.
    Du J; Campau E; Soragni E; Ku S; Puckett JW; Dervan PB; Gottesfeld JM
    J Biol Chem; 2012 Aug; 287(35):29861-72. PubMed ID: 22798143
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A novel GAA-repeat-expansion-based mouse model of Friedreich's ataxia.
    Anjomani Virmouni S; Ezzatizadeh V; Sandi C; Sandi M; Al-Mahdawi S; Chutake Y; Pook MA
    Dis Model Mech; 2015 Mar; 8(3):225-35. PubMed ID: 25681319
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Friedreich's ataxia--a case of aberrant transcription termination?
    Butler JS; Napierala M
    Transcription; 2015; 6(2):33-6. PubMed ID: 25831023
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transcriptional profiling of isogenic Friedreich ataxia neurons and effect of an HDAC inhibitor on disease signatures.
    Lai JI; Nachun D; Petrosyan L; Throesch B; Campau E; Gao F; Baldwin KK; Coppola G; Gottesfeld JM; Soragni E
    J Biol Chem; 2019 Feb; 294(6):1846-1859. PubMed ID: 30552117
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DNA Base Damage Repair Crosstalks with Chromatin Structures to Contract Expanded GAA Repeats in Friedreich's Ataxia.
    Lai Y; Diaz N; Armbrister R; Agoulnik I; Liu Y
    Biomolecules; 2024 Jul; 14(7):. PubMed ID: 39062522
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A GAA repeat expansion reporter model of Friedreich's ataxia recapitulates the genomic context and allows rapid screening of therapeutic compounds.
    Lufino MM; Silva AM; Németh AH; Alegre-Abarrategui J; Russell AJ; Wade-Martins R
    Hum Mol Genet; 2013 Dec; 22(25):5173-87. PubMed ID: 23943791
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Generation and characterization of iPSC lines from Friedreich's ataxia patient (FRDA) with GAA.TTC repeat expansion in the Frataxin (FXN) gene's first intron (IGIBi016-A) and a non-FRDA healthy control individual (IGIBi017-A).
    Ahmad I; Kamai A; Zahra S; Kapoor H; Kumar Srivastava A; Faruq M
    Stem Cell Res; 2024 Jun; 77():103382. PubMed ID: 38484450
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Generation of two human induced pluripotent stem cell lines, IGIBi012-A and IGIBi013-A from Friedreich's ataxia (FRDA) patients with homozygous GAA repeat expansion in FXN gene.
    Ahmad I; Kapoor H; Srivastava AK; Faruq M
    Stem Cell Res; 2024 Apr; 76():103340. PubMed ID: 38367363
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Generation of transgene-free iPSC lines from three patients with Friedreich's ataxia (FRDA) carrying GAA triplet expansions in the first intron of FXN gene.
    Kelekçi S; Uğurlu-Çimen D; Demir AB; Özçimen B; Burak Yıldız A; Batuhan Karakuş M; Börklü Yücel E; Önder TT
    Stem Cell Res; 2021 Jul; 54():102438. PubMed ID: 34214898
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Stalled DNA Replication Forks at the Endogenous GAA Repeats Drive Repeat Expansion in Friedreich's Ataxia Cells.
    Gerhardt J; Bhalla AD; Butler JS; Puckett JW; Dervan PB; Rosenwaks Z; Napierala M
    Cell Rep; 2016 Aug; 16(5):1218-1227. PubMed ID: 27425605
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Excision of the expanded GAA repeats corrects cardiomyopathy phenotypes of iPSC-derived Friedreich's ataxia cardiomyocytes.
    Li J; Rozwadowska N; Clark A; Fil D; Napierala JS; Napierala M
    Stem Cell Res; 2019 Oct; 40():101529. PubMed ID: 31446150
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Friedreich's ataxia: new insights.
    Krasilnikova MM; Humphries CL; Shinsky EM
    Emerg Top Life Sci; 2023 Dec; 7(3):313-323. PubMed ID: 37698160
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A Comprehensive Transcriptome Analysis Identifies FXN and BDNF as Novel Targets of miRNAs in Friedreich's Ataxia Patients.
    Misiorek JO; Schreiber AM; Urbanek-Trzeciak MO; Jazurek-Ciesiołka M; Hauser LA; Lynch DR; Napierala JS; Napierala M
    Mol Neurobiol; 2020 Jun; 57(6):2639-2653. PubMed ID: 32291635
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich's ataxia.
    Hick A; Wattenhofer-Donzé M; Chintawar S; Tropel P; Simard JP; Vaucamps N; Gall D; Lambot L; André C; Reutenauer L; Rai M; Teletin M; Messaddeq N; Schiffmann SN; Viville S; Pearson CE; Pandolfo M; Puccio H
    Dis Model Mech; 2013 May; 6(3):608-21. PubMed ID: 23136396
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Heterochromatinization induced by GAA-repeat hyperexpansion in Friedreich's ataxia can be reduced upon HDAC inhibition by vitamin B3.
    Chan PK; Torres R; Yandim C; Law PP; Khadayate S; Mauri M; Grosan C; Chapman-Rothe N; Giunti P; Pook M; Festenstein R
    Hum Mol Genet; 2013 Jul; 22(13):2662-75. PubMed ID: 23474817
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Somatic instability of the expanded GAA repeats in Friedreich's ataxia.
    Long A; Napierala JS; Polak U; Hauser L; Koeppen AH; Lynch DR; Napierala M
    PLoS One; 2017; 12(12):e0189990. PubMed ID: 29261783
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Complete FXN deletion in a patient with Friedreich's ataxia.
    van den Ouweland AM; van Minkelen R; Bolman GM; Wouters CH; Becht-Noordermeer C; Deelen WH; Deelen-Manders JM; Ippel EP; Saris J; Halley DJ
    Genet Test Mol Biomarkers; 2012 Sep; 16(9):1015-8. PubMed ID: 22691228
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Generation and characterization of two human iPSC lines, IGIBi014-A and IGIBi015-A, from Friedreich's ataxia (FRDA) patients with pathogenic (GAA/TTC)n repeat expansion in first intron of the Frataxin (FXN) gene.
    Ahmad I; Kapoor H; Kumar Srivastava A; Faruq M
    Stem Cell Res; 2024 Feb; 74():103289. PubMed ID: 38141359
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.