These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

907 related articles for article (PubMed ID: 21041309)

  • 1. BH3 domains other than Bim and Bid can directly activate Bax/Bak.
    Du H; Wolf J; Schafer B; Moldoveanu T; Chipuk JE; Kuwana T
    J Biol Chem; 2011 Jan; 286(1):491-501. PubMed ID: 21041309
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner.
    Kazi A; Sun J; Doi K; Sung SS; Takahashi Y; Yin H; Rodriguez JM; Becerril J; Berndt N; Hamilton AD; Wang HG; Sebti SM
    J Biol Chem; 2011 Mar; 286(11):9382-92. PubMed ID: 21148306
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak.
    Willis SN; Fletcher JI; Kaufmann T; van Delft MF; Chen L; Czabotar PE; Ierino H; Lee EF; Fairlie WD; Bouillet P; Strasser A; Kluck RM; Adams JM; Huang DC
    Science; 2007 Feb; 315(5813):856-9. PubMed ID: 17289999
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax.
    Hockings C; Anwari K; Ninnis RL; Brouwer J; O'Hely M; Evangelista M; Hinds MG; Czabotar PE; Lee EF; Fairlie WD; Dewson G; Kluck RM
    Cell Death Dis; 2015 Apr; 6(4):e1735. PubMed ID: 25906158
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Distinct lipid effects on tBid and Bim activation of membrane permeabilization by pro-apoptotic Bax.
    Shamas-Din A; Bindner S; Chi X; Leber B; Andrews DW; Fradin C
    Biochem J; 2015 May; 467(3):495-505. PubMed ID: 25714678
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An interconnected hierarchical model of cell death regulation by the BCL-2 family.
    Chen HC; Kanai M; Inoue-Yamauchi A; Tu HC; Huang Y; Ren D; Kim H; Takeda S; Reyna DE; Chan PM; Ganesan YT; Liao CP; Gavathiotis E; Hsieh JJ; Cheng EH
    Nat Cell Biol; 2015 Oct; 17(10):1270-81. PubMed ID: 26344567
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies.
    Kim H; Rafiuddin-Shah M; Tu HC; Jeffers JR; Zambetti GP; Hsieh JJ; Cheng EH
    Nat Cell Biol; 2006 Dec; 8(12):1348-58. PubMed ID: 17115033
    [TBL] [Abstract][Full Text] [Related]  

  • 8. BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program.
    Ren D; Tu HC; Kim H; Wang GX; Bean GR; Takeuchi O; Jeffers JR; Zambetti GP; Hsieh JJ; Cheng EH
    Science; 2010 Dec; 330(6009):1390-3. PubMed ID: 21127253
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization.
    Yamaguchi R; Lartigue L; Perkins G; Scott RT; Dixit A; Kushnareva Y; Kuwana T; Ellisman MH; Newmeyer DD
    Mol Cell; 2008 Aug; 31(4):557-569. PubMed ID: 18691924
    [TBL] [Abstract][Full Text] [Related]  

  • 10. BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly.
    Kuwana T; Bouchier-Hayes L; Chipuk JE; Bonzon C; Sullivan BA; Green DR; Newmeyer DD
    Mol Cell; 2005 Feb; 17(4):525-35. PubMed ID: 15721256
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Bax/Bak activation in the absence of Bid, Bim, Puma, and p53.
    Zhang J; Huang K; O'Neill KL; Pang X; Luo X
    Cell Death Dis; 2016 Jun; 7(6):e2266. PubMed ID: 27310874
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BH3-only proteins target BCL-xL/MCL-1, not BAX/BAK, to initiate apoptosis.
    Huang K; O'Neill KL; Li J; Zhou W; Han N; Pang X; Wu W; Struble L; Borgstahl G; Liu Z; Zhang L; Luo X
    Cell Res; 2019 Nov; 29(11):942-952. PubMed ID: 31551537
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular basis for Bcl-2 homology 3 domain recognition in the Bcl-2 protein family: identification of conserved hot spot interactions.
    Moroy G; Martin E; Dejaegere A; Stote RH
    J Biol Chem; 2009 Jun; 284(26):17499-511. PubMed ID: 19293158
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Glucose induces pancreatic islet cell apoptosis that requires the BH3-only proteins Bim and Puma and multi-BH domain protein Bax.
    McKenzie MD; Jamieson E; Jansen ES; Scott CL; Huang DC; Bouillet P; Allison J; Kay TW; Strasser A; Thomas HE
    Diabetes; 2010 Mar; 59(3):644-52. PubMed ID: 19959756
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis.
    Kim H; Tu HC; Ren D; Takeuchi O; Jeffers JR; Zambetti GP; Hsieh JJ; Cheng EH
    Mol Cell; 2009 Nov; 36(3):487-99. PubMed ID: 19917256
    [TBL] [Abstract][Full Text] [Related]  

  • 16. B cell lymphoma-2 (BCL-2) homology domain 3 (BH3) mimetics demonstrate differential activities dependent upon the functional repertoire of pro- and anti-apoptotic BCL-2 family proteins.
    Renault TT; Elkholi R; Bharti A; Chipuk JE
    J Biol Chem; 2014 Sep; 289(38):26481-26491. PubMed ID: 25096574
    [TBL] [Abstract][Full Text] [Related]  

  • 17. BIM and tBID are not mechanistically equivalent when assisting BAX to permeabilize bilayer membranes.
    Terrones O; Etxebarria A; Landajuela A; Landeta O; Antonsson B; BasaƱez G
    J Biol Chem; 2008 Mar; 283(12):7790-803. PubMed ID: 18195012
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Examining BCL-2 family function with large unilamellar vesicles.
    Asciolla JJ; Renault TT; Chipuk JE
    J Vis Exp; 2012 Oct; (68):. PubMed ID: 23070252
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bax- or Bak-induced mitochondrial fission can be uncoupled from cytochrome C release.
    Sheridan C; Delivani P; Cullen SP; Martin SJ
    Mol Cell; 2008 Aug; 31(4):570-585. PubMed ID: 18722181
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural insight into BH3 domain binding of vaccinia virus antiapoptotic F1L.
    Campbell S; Thibault J; Mehta N; Colman PM; Barry M; Kvansakul M
    J Virol; 2014 Aug; 88(15):8667-77. PubMed ID: 24850748
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 46.