These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

271 related articles for article (PubMed ID: 21041639)

  • 21. PIP3-binding proteins promote age-dependent protein aggregation and limit survival in C. elegans.
    Ayyadevara S; Balasubramaniam M; Johnson J; Alla R; Mackintosh SG; Shmookler Reis RJ
    Oncotarget; 2016 Aug; 7(31):48870-48886. PubMed ID: 27429199
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Direct evidence for the action of phosphatidylinositol (3,4,5)-trisphosphate-mediated signal transduction in the 2-cell mouse embryo.
    Li Y; Chandrakanthan V; Day ML; O'Neill C
    Biol Reprod; 2007 Nov; 77(5):813-21. PubMed ID: 17634444
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications.
    Carnero A; Blanco-Aparicio C; Renner O; Link W; Leal JF
    Curr Cancer Drug Targets; 2008 May; 8(3):187-98. PubMed ID: 18473732
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Structure of autoinhibited Akt1 reveals mechanism of PIP
    Truebestein L; Hornegger H; Anrather D; Hartl M; Fleming KD; Stariha JTB; Pardon E; Steyaert J; Burke JE; Leonard TA
    Proc Natl Acad Sci U S A; 2021 Aug; 118(33):. PubMed ID: 34385319
    [TBL] [Abstract][Full Text] [Related]  

  • 25. In vitro and in vivo activity of novel small-molecule inhibitors targeting the pleckstrin homology domain of protein kinase B/AKT.
    Moses SA; Ali MA; Zuohe S; Du-Cuny L; Zhou LL; Lemos R; Ihle N; Skillman AG; Zhang S; Mash EA; Powis G; Meuillet EJ
    Cancer Res; 2009 Jun; 69(12):5073-81. PubMed ID: 19491272
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Binding of the PH and polybasic C-terminal domains of ARNO to phosphoinositides and to acidic lipids.
    Macia E; Paris S; Chabre M
    Biochemistry; 2000 May; 39(19):5893-901. PubMed ID: 10801341
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Specific detection of phosphatidylinositol 3,4,5-trisphosphate binding proteins by the PIP3 analogue beads: an application for rapid purification of the PIP3 binding proteins.
    Shirai T; Tanaka K; Terada Y; Sawada T; Shirai R; Hashimoto Y; Nagata S; Iwamatsu A; Okawa K; Li S; Hattori S; Mano H; Fukui Y
    Biochim Biophys Acta; 1998 Apr; 1402(3):292-302. PubMed ID: 9606988
    [TBL] [Abstract][Full Text] [Related]  

  • 28. 3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase.
    Alessi DR; Deak M; Casamayor A; Caudwell FB; Morrice N; Norman DG; Gaffney P; Reese CB; MacDougall CN; Harbison D; Ashworth A; Bownes M
    Curr Biol; 1997 Oct; 7(10):776-89. PubMed ID: 9368760
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Modulation of oncogenic DBL activity by phosphoinositol phosphate binding to pleckstrin homology domain.
    Russo C; Gao Y; Mancini P; Vanni C; Porotto M; Falasca M; Torrisi MR; Zheng Y; Eva A
    J Biol Chem; 2001 Jun; 276(22):19524-31. PubMed ID: 11278560
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Identification and characterization of pleckstrin-homology-domain-dependent and isoenzyme-specific Akt inhibitors.
    Barnett SF; Defeo-Jones D; Fu S; Hancock PJ; Haskell KM; Jones RE; Kahana JA; Kral AM; Leander K; Lee LL; Malinowski J; McAvoy EM; Nahas DD; Robinson RG; Huber HE
    Biochem J; 2005 Jan; 385(Pt 2):399-408. PubMed ID: 15456405
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Regulation of PTEN inhibition by the pleckstrin homology domain of P-REX2 during insulin signaling and glucose homeostasis.
    Hodakoski C; Hopkins BD; Barrows D; Mense SM; Keniry M; Anderson KE; Kern PA; Hawkins PT; Stephens LR; Parsons R
    Proc Natl Acad Sci U S A; 2014 Jan; 111(1):155-60. PubMed ID: 24367090
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Critical role of the pleckstrin homology and cysteine-rich domains in Vav signaling and transforming activity.
    Palmby TR; Abe K; Der CJ
    J Biol Chem; 2002 Oct; 277(42):39350-9. PubMed ID: 12177050
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Phosphatidylinositol Phosphate 5-Kinase Iγ and Phosphoinositide 3-Kinase/Akt Signaling Couple to Promote Oncogenic Growth.
    Thapa N; Choi S; Tan X; Wise T; Anderson RA
    J Biol Chem; 2015 Jul; 290(30):18843-54. PubMed ID: 26070568
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Phosphatidylinositol (3,4) bisphosphate-specific phosphatases and effector proteins: A distinct branch of PI3K signaling.
    Li H; Marshall AJ
    Cell Signal; 2015 Sep; 27(9):1789-98. PubMed ID: 26022180
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change.
    Milburn CC; Deak M; Kelly SM; Price NC; Alessi DR; Van Aalten DM
    Biochem J; 2003 Nov; 375(Pt 3):531-8. PubMed ID: 12964941
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Specific inhibition of the Akt1 pleckstrin homology domain by D-3-deoxy-phosphatidyl-myo-inositol analogues.
    Meuillet EJ; Mahadevan D; Vankayalapati H; Berggren M; Williams R; Coon A; Kozikowski AP; Powis G
    Mol Cancer Ther; 2003 Apr; 2(4):389-99. PubMed ID: 12700283
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Comprehensive identification of PIP3-regulated PH domains from C. elegans to H. sapiens by model prediction and live imaging.
    Park WS; Heo WD; Whalen JH; O'Rourke NA; Bryan HM; Meyer T; Teruel MN
    Mol Cell; 2008 May; 30(3):381-92. PubMed ID: 18471983
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Interaction between the Btk PH domain and phosphatidylinositol-3,4,5-trisphosphate directly regulates Btk.
    Saito K; Scharenberg AM; Kinet JP
    J Biol Chem; 2001 May; 276(19):16201-6. PubMed ID: 11279148
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Tirucallic acids are novel pleckstrin homology domain-dependent Akt inhibitors inducing apoptosis in prostate cancer cells.
    Estrada AC; Syrovets T; Pitterle K; Lunov O; Büchele B; Schimana-Pfeifer J; Schmidt T; Morad SA; Simmet T
    Mol Pharmacol; 2010 Mar; 77(3):378-87. PubMed ID: 20018812
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Small-molecule inhibitors of the PI3K signaling network.
    McNamara CR; Degterev A
    Future Med Chem; 2011 Apr; 3(5):549-65. PubMed ID: 21526896
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 14.