BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 21043491)

  • 1. Total synthesis of bryostatin 16 using a Pd-catalyzed diyne coupling as macrocyclization method and synthesis of C20-epi-bryostatin 7 as a potent anticancer agent.
    Trost BM; Dong G
    J Am Chem Soc; 2010 Nov; 132(46):16403-16. PubMed ID: 21043491
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Total syntheses of bryostatins: synthesis of two ring-expanded bryostatin analogues and the development of a new-generation strategy to access the C7-C27 fragment.
    Trost BM; Yang H; Dong G
    Chemistry; 2011 Aug; 17(35):9789-805. PubMed ID: 21780195
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis of seco-B-ring bryostatin analogue WN-1 via C-C bond-forming hydrogenation: critical contribution of the B-ring in determining bryostatin-like and phorbol 12-myristate 13-acetate-like properties.
    Andrews IP; Ketcham JM; Blumberg PM; Kedei N; Lewin NE; Peach ML; Krische MJ
    J Am Chem Soc; 2014 Sep; 136(38):13209-16. PubMed ID: 25207655
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Atom-economic and stereoselective syntheses of the ring a and B subunits of the bryostatins.
    Trost BM; Yang H; Brindle CS; Dong G
    Chemistry; 2011 Aug; 17(35):9777-88. PubMed ID: 21774000
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of a des-B-ring bryostatin analogue leads to an unexpected ring expansion of the bryolactone core.
    Kraft MB; Poudel YB; Kedei N; Lewin NE; Peach ML; Blumberg PM; Keck GE
    J Am Chem Soc; 2014 Sep; 136(38):13202-8. PubMed ID: 25207434
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Total synthesis of bryostatin 16 using atom-economical and chemoselective approaches.
    Trost BM; Dong G
    Nature; 2008 Nov; 456(7221):485-8. PubMed ID: 19037312
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Total synthesis of bryostatins: the development of methodology for the atom-economic and stereoselective synthesis of the ring C subunit.
    Trost BM; Frontier AJ; Thiel OR; Yang H; Dong G
    Chemistry; 2011 Aug; 17(35):9762-76. PubMed ID: 21793057
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Substitution on the A-ring confers to bryopyran analogues the unique biological activity characteristic of bryostatins and distinct from that of the phorbol esters.
    Keck GE; Poudel YB; Welch DS; Kraft MB; Truong AP; Stephens JC; Kedei N; Lewin NE; Blumberg PM
    Org Lett; 2009 Feb; 11(3):593-6. PubMed ID: 19113896
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Total synthesis of bryostatin 9.
    Wender PA; Schrier AJ
    J Am Chem Soc; 2011 Jun; 133(24):9228-31. PubMed ID: 21618969
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evaluation of Chromane-Based Bryostatin Analogues Prepared via Hydrogen-Mediated C-C Bond Formation: Potency Does Not Confer Bryostatin-like Biology.
    Ketcham JM; Volchkov I; Chen TY; Blumberg PM; Kedei N; Lewin NE; Krische MJ
    J Am Chem Soc; 2016 Oct; 138(40):13415-13423. PubMed ID: 27676096
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthetic studies on the bryostatins: preparation of a truncated BC-ring intermediate by pyran annulation.
    Keck GE; Truong AP
    Org Lett; 2005 May; 7(11):2149-52. PubMed ID: 15901156
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthetic studies on the bryostatins: synthetic routes to analogues containing the tricyclic macrolactone core.
    Keck GE; Truong AP
    Org Lett; 2005 May; 7(11):2153-6. PubMed ID: 15901157
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Total synthesis of bryostatin 3.
    Trost BM; Wang Y; Buckl AK; Huang Z; Nguyen MH; Kuzmina O
    Science; 2020 May; 368(6494):1007-1011. PubMed ID: 32467391
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of the C8 gem-dimethyl group of bryostatin 1 on its unique pattern of biological activity.
    Keck GE; Poudel YB; Rudra A; Stephens JC; Kedei N; Lewin NE; Blumberg PM
    Bioorg Med Chem Lett; 2012 Jun; 22(12):4084-8. PubMed ID: 22579485
    [TBL] [Abstract][Full Text] [Related]  

  • 15. New approaches to the total synthesis of the bryostatin antitumor macrolides.
    Hale KJ; Manaviazar S
    Chem Asian J; 2010 Apr; 5(4):704-54. PubMed ID: 20354984
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The design, synthesis, and evaluation of C7 diversified bryostatin analogs reveals a hot spot for PKC affinity.
    Wender PA; Verma VA
    Org Lett; 2008 Aug; 10(15):3331-4. PubMed ID: 18588309
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Convergent assembly of highly potent analogues of bryostatin 1 via pyran annulation: bryostatin look-alikes that mimic phorbol ester function.
    Keck GE; Kraft MB; Truong AP; Li W; Sanchez CC; Kedei N; Lewin NE; Blumberg PM
    J Am Chem Soc; 2008 May; 130(21):6660-1. PubMed ID: 18452293
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Catalysis in the total synthesis of bryostatin 16.
    Miller AK
    Angew Chem Int Ed Engl; 2009; 48(18):3221-3. PubMed ID: 19259997
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Efficient synthetic access to a new family of highly potent bryostatin analogues via a Prins-driven macrocyclization strategy.
    Wender PA; Dechristopher BA; Schrier AJ
    J Am Chem Soc; 2008 May; 130(21):6658-9. PubMed ID: 18452292
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Isolation, analytical measurements, and cell line studies of the iron-bryostatin-1 complex.
    Plummer S; Manning T; Baker T; McGreggor T; Patel M; Wylie G; Phillips D
    Bioorg Med Chem Lett; 2016 May; 26(10):2489-2497. PubMed ID: 27068183
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.