These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
140 related articles for article (PubMed ID: 21044031)
1. Parallel artificial membrane permeability assay (PAMPA) - Is it better than Caco-2 for human passive permeability prediction? Reis JM; Sinkó B; Serra CH Mini Rev Med Chem; 2010 Oct; 10(11):1071-6. PubMed ID: 21044031 [TBL] [Abstract][Full Text] [Related]
2. Evaluation of various PAMPA models to identify the most discriminating method for the prediction of BBB permeability. Mensch J; Melis A; Mackie C; Verreck G; Brewster ME; Augustijns P Eur J Pharm Biopharm; 2010 Mar; 74(3):495-502. PubMed ID: 20067834 [TBL] [Abstract][Full Text] [Related]
3. Parallel artificial membrane permeability assay (PAMPA) combined with a 10-day multiscreen Caco-2 cell culture as a tool for assessing new drug candidates. Masungi C; Mensch J; Van Dijck A; Borremans C; Willems B; Mackie C; Noppe M; Brewster ME Pharmazie; 2008 Mar; 63(3):194-9. PubMed ID: 18444507 [TBL] [Abstract][Full Text] [Related]
4. Relationships between structure and high-throughput screening permeability of peptide derivatives and related compounds with artificial membranes: application to prediction of Caco-2 cell permeability. Ano R; Kimura Y; Shima M; Matsuno R; Ueno T; Akamatsu M Bioorg Med Chem; 2004 Jan; 12(1):257-64. PubMed ID: 14697791 [TBL] [Abstract][Full Text] [Related]
5. Relationships between structure and high-throughput screening permeability of diverse drugs with artificial membranes: application to prediction of Caco-2 cell permeability. Fujikawa M; Ano R; Nakao K; Shimizu R; Akamatsu M Bioorg Med Chem; 2005 Aug; 13(15):4721-32. PubMed ID: 15936203 [TBL] [Abstract][Full Text] [Related]
6. Combined application of parallel artificial membrane permeability assay and Caco-2 permeability assays in drug discovery. Kerns EH; Di L; Petusky S; Farris M; Ley R; Jupp P J Pharm Sci; 2004 Jun; 93(6):1440-53. PubMed ID: 15124203 [TBL] [Abstract][Full Text] [Related]
7. Clearance-dependent underprediction of in vivo intrinsic clearance from human hepatocytes: comparison with permeabilities from artificial membrane (PAMPA) assay, in silico and caco-2 assay, for 65 drugs. Hallifax D; Turlizzi E; Zanelli U; Houston JB Eur J Pharm Sci; 2012 Apr; 45(5):570-4. PubMed ID: 22214813 [TBL] [Abstract][Full Text] [Related]
8. Comparison of in vitro models for the prediction of compound absorption across the human intestinal mucosa. Miret S; Abrahamse L; de Groene EM J Biomol Screen; 2004 Oct; 9(7):598-606. PubMed ID: 15475479 [TBL] [Abstract][Full Text] [Related]
9. PAMPA--critical factors for better predictions of absorption. Avdeef A; Bendels S; Di L; Faller B; Kansy M; Sugano K; Yamauchi Y J Pharm Sci; 2007 Nov; 96(11):2893-909. PubMed ID: 17803196 [TBL] [Abstract][Full Text] [Related]
10. Transport mechanisms of flavanone aglycones across Caco-2 cell monolayers and artificial PAMPA membranes. Kobayashi S; Nagai T; Konishi Y; Tanabe S; Morimoto K; Ogihara T J Pharm Pharmacol; 2012 Jan; 64(1):52-60. PubMed ID: 22150672 [TBL] [Abstract][Full Text] [Related]
11. In silico prediction of human oral absorption based on QSAR analyses of PAMPA permeability. Akamatsu M; Fujikawa M; Nakao K; Shimizu R Chem Biodivers; 2009 Nov; 6(11):1845-66. PubMed ID: 19937826 [TBL] [Abstract][Full Text] [Related]
12. Caco-2 permeability of weakly basic drugs predicted with the double-sink PAMPA pKa(flux) method. Avdeef A; Artursson P; Neuhoff S; Lazorova L; Gråsjö J; Tavelin S Eur J Pharm Sci; 2005 Mar; 24(4):333-49. PubMed ID: 15734300 [TBL] [Abstract][Full Text] [Related]
13. PAMPA--a drug absorption in vitro model 7. Comparing rat in situ, Caco-2, and PAMPA permeability of fluoroquinolones. Bermejo M; Avdeef A; Ruiz A; Nalda R; Ruell JA; Tsinman O; González I; Fernández C; Sánchez G; Garrigues TM; Merino V Eur J Pharm Sci; 2004 Mar; 21(4):429-41. PubMed ID: 14998573 [TBL] [Abstract][Full Text] [Related]
15. Correlation between PAMPA permeability and cellular activities of hepatitis C virus protease inhibitors. Li C; Nair L; Liu T; Li F; Pichardo J; Agrawal S; Chase R; Tong X; Uss AS; Bogen S; Njoroge FG; Morrison RA; Cheng KC Biochem Pharmacol; 2008 Mar; 75(5):1186-97. PubMed ID: 18164692 [TBL] [Abstract][Full Text] [Related]
16. QSAR study on permeability of hydrophobic compounds with artificial membranes. Fujikawa M; Nakao K; Shimizu R; Akamatsu M Bioorg Med Chem; 2007 Jun; 15(11):3756-67. PubMed ID: 17418579 [TBL] [Abstract][Full Text] [Related]
17. Highly predictive and interpretable models for PAMPA permeability. Sun H; Nguyen K; Kerns E; Yan Z; Yu KR; Shah P; Jadhav A; Xu X Bioorg Med Chem; 2017 Feb; 25(3):1266-1276. PubMed ID: 28082071 [TBL] [Abstract][Full Text] [Related]
18. QSAR application for the prediction of compound permeability with in silico descriptors in practical use. Nakao K; Fujikawa M; Shimizu R; Akamatsu M J Comput Aided Mol Des; 2009 May; 23(5):309-19. PubMed ID: 19241121 [TBL] [Abstract][Full Text] [Related]