83 related articles for article (PubMed ID: 21044742)
1. Fatty acid bile acid conjugate inhibits hepatic stearoyl coenzyme A desaturase and is non-atherogenic.
Leikin-Frenkel A; Gonen A; Shaish A; Goldiner I; Leikin-Gobbi D; Konikoff FM; Harats D; Gilat T
Arch Med Res; 2010 Aug; 41(6):397-404. PubMed ID: 21044742
[TBL] [Abstract][Full Text] [Related]
2. Direct effect of an acyl-CoA:cholesterol acyltransferase inhibitor, F-1394, on atherosclerosis in apolipoprotein E and low density lipoprotein receptor double knockout mice.
Chiwata T; Aragane K; Fujinami K; Kojima K; Ishibashi S; Yamada N; Kusunoki J
Br J Pharmacol; 2001 Aug; 133(7):1005-12. PubMed ID: 11487509
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of glycosphingolipid synthesis induces a profound reduction of plasma cholesterol and inhibits atherosclerosis development in APOE*3 Leiden and low-density lipoprotein receptor-/- mice.
Bietrix F; Lombardo E; van Roomen CP; Ottenhoff R; Vos M; Rensen PC; Verhoeven AJ; Aerts JM; Groen AK
Arterioscler Thromb Vasc Biol; 2010 May; 30(5):931-7. PubMed ID: 20167657
[TBL] [Abstract][Full Text] [Related]
4. Hepatic cholesterol and bile acid synthesis, low-density lipoprotein receptor function, and plasma and fecal sterol levels in mice: effects of apolipoprotein E deficiency and probucol or phytosterol treatment.
Moghadasian MH; Nguyen LB; Shefer S; Salen G; Batta AK; Frohlich JJ
Metabolism; 2001 Jun; 50(6):708-14. PubMed ID: 11398149
[TBL] [Abstract][Full Text] [Related]
5. A biphasic response of hepatobiliary cholesterol metabolism to dietary fat at the onset of obesity in the mouse.
Roy S; Hyogo H; Yadav SK; Wu MK; Jelicks LA; Locker JD; Frank PG; Lisanti MP; Silver DL; Cohen DE
Hepatology; 2005 Apr; 41(4):887-95. PubMed ID: 15793852
[TBL] [Abstract][Full Text] [Related]
6. Dyslipidemia and atherosclerosis induced by chronic intermittent hypoxia are attenuated by deficiency of stearoyl coenzyme A desaturase.
Savransky V; Jun J; Li J; Nanayakkara A; Fonti S; Moser AB; Steele KE; Schweitzer MA; Patil SP; Bhanot S; Schwartz AR; Polotsky VY
Circ Res; 2008 Nov; 103(10):1173-80. PubMed ID: 18832746
[TBL] [Abstract][Full Text] [Related]
7. Treatment of preestablished diet-induced fatty liver by oral fatty acid-bile acid conjugates in rodents.
Leikin-Frenkel A; Goldiner I; Leikin-Gobbi D; Rosenberg R; Bonen H; Litvak A; Bernheim J; Konikoff FM; Gilat T
Eur J Gastroenterol Hepatol; 2008 Dec; 20(12):1205-13. PubMed ID: 18989145
[TBL] [Abstract][Full Text] [Related]
8. Obesity potentiates development of fatty liver and insulin resistance, but not atherosclerosis, in high-fat diet-fed agouti LDLR-deficient mice.
Coenen KR; Hasty AH
Am J Physiol Endocrinol Metab; 2007 Aug; 293(2):E492-9. PubMed ID: 17566116
[TBL] [Abstract][Full Text] [Related]
9. Urotensin II receptor knockout mice on an ApoE knockout background fed a high-fat diet exhibit an enhanced hyperlipidemic and atherosclerotic phenotype.
Bousette N; D'Orleans-Juste P; Kiss RS; You Z; Genest J; Al-Ramli W; Qureshi ST; Gramolini A; Behm D; Ohlstein EH; Harrison SM; Douglas SA; Giaid A
Circ Res; 2009 Sep; 105(7):686-95, 19 p following 695. PubMed ID: 19696412
[TBL] [Abstract][Full Text] [Related]
10. Development of a high-throughput screening assay for stearoyl-CoA desaturase using rat liver microsomes, deuterium labeled stearoyl-CoA and mass spectrometry.
Soulard P; McLaughlin M; Stevens J; Connolly B; Coli R; Wang L; Moore J; Kuo MS; LaMarr WA; Ozbal CC; Bhat BG
Anal Chim Acta; 2008 Oct; 627(1):105-11. PubMed ID: 18790133
[TBL] [Abstract][Full Text] [Related]
11. Discovery of potent and liver-selective stearoyl-CoA desaturase (SCD) inhibitors in an acyclic linker series.
Lachance N; Guiral S; Huang Z; Leclerc JP; Li CS; Oballa RM; Ramtohul YK; Wang H; Wu J; Zhang L
Bioorg Med Chem Lett; 2012 Jan; 22(1):623-7. PubMed ID: 22101133
[TBL] [Abstract][Full Text] [Related]
12. 2-Aryl benzimidazoles: human SCD1-specific stearoyl coenzyme-A desaturase inhibitors.
Powell DA; Ramtohul Y; Lebrun ME; Oballa R; Bhat S; Falgueyret JP; Guiral S; Huang Z; Skorey K; Tawa P; Zhang L
Bioorg Med Chem Lett; 2010 Nov; 20(22):6366-9. PubMed ID: 20933412
[TBL] [Abstract][Full Text] [Related]
13. Conversion of systemically-distributed triazole-based stearoyl-CoA desaturase (SCD) uHTS hits into liver-targeted SCD inhibitors.
Leclerc JP; Falgueyret JP; Girardin M; Guay J; Guiral S; Huang Z; Li CS; Oballa R; Ramtohul YK; Skorey K; Tawa P; Wang H; Zhang L
Bioorg Med Chem Lett; 2011 Nov; 21(21):6505-9. PubMed ID: 21924609
[TBL] [Abstract][Full Text] [Related]
14. Thiazole analog as stearoyl-CoA desaturase 1 inhibitor.
Li CS; Belair L; Guay J; Murgasva R; Sturkenboom W; Ramtohul YK; Zhang L; Huang Z
Bioorg Med Chem Lett; 2009 Sep; 19(17):5214-7. PubMed ID: 19632834
[TBL] [Abstract][Full Text] [Related]
15. Naringenin decreases progression of atherosclerosis by improving dyslipidemia in high-fat-fed low-density lipoprotein receptor-null mice.
Mulvihill EE; Assini JM; Sutherland BG; DiMattia AS; Khami M; Koppes JB; Sawyez CG; Whitman SC; Huff MW
Arterioscler Thromb Vasc Biol; 2010 Apr; 30(4):742-8. PubMed ID: 20110573
[TBL] [Abstract][Full Text] [Related]
16. Discovery of potent and liver-targeted stearoyl-CoA desaturase (SCD) inhibitors in a bispyrrolidine series.
Lachance N; Gareau Y; Guiral S; Huang Z; Isabel E; Leclerc JP; Léger S; Martins E; Nadeau C; Oballa RM; Ouellet SG; Powell DA; Ramtohul YK; Tranmer GK; Trinh T; Wang H; Zhang L
Bioorg Med Chem Lett; 2012 Jan; 22(2):980-4. PubMed ID: 22209206
[TBL] [Abstract][Full Text] [Related]
17. Poly(ADP-ribose) polymerase inhibition reduces atherosclerotic plaque size and promotes factors of plaque stability in apolipoprotein E-deficient mice: effects on macrophage recruitment, nuclear factor-kappaB nuclear translocation, and foam cell death.
Oumouna-Benachour K; Hans CP; Suzuki Y; Naura A; Datta R; Belmadani S; Fallon K; Woods C; Boulares AH
Circulation; 2007 May; 115(18):2442-50. PubMed ID: 17438151
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of stearoyl-coenzyme A desaturase 1 dissociates insulin resistance and obesity from atherosclerosis.
Brown JM; Chung S; Sawyer JK; Degirolamo C; Alger HM; Nguyen T; Zhu X; Duong MN; Wibley AL; Shah R; Davis MA; Kelley K; Wilson MD; Kent C; Parks JS; Rudel LL
Circulation; 2008 Sep; 118(14):1467-75. PubMed ID: 18794388
[TBL] [Abstract][Full Text] [Related]
19. CD137 (4-1BB) deficiency reduces atherosclerosis in hyperlipidemic mice.
Jeon HJ; Choi JH; Jung IH; Park JG; Lee MR; Lee MN; Kim B; Yoo JY; Jeong SJ; Kim DY; Park JE; Park HY; Kwack K; Choi BK; Kwon BS; Oh GT
Circulation; 2010 Mar; 121(9):1124-33. PubMed ID: 20176988
[TBL] [Abstract][Full Text] [Related]
20. Effect of curcumin on atherosclerosis in apoE/LDLR-double knockout mice.
Olszanecki R; Jawień J; Gajda M; Mateuszuk L; Gebska A; Korabiowska M; Chłopicki S; Korbut R
J Physiol Pharmacol; 2005 Dec; 56(4):627-35. PubMed ID: 16391419
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
