BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

144 related articles for article (PubMed ID: 21050889)

  • 21. Molecular characterization of the cynomolgus monkey Macaca fascicularis steroidogenic enzymes belonging to the aldo-keto reductase family.
    Liu H; Bellemare V; Labrie F; Luu-The V
    J Steroid Biochem Mol Biol; 2007 Apr; 104(1-2):75-80. PubMed ID: 17257829
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Inhibitors of type 5 17β-hydroxysteroid dehydrogenase (AKR1C3): overview and structural insights.
    Byrns MC; Jin Y; Penning TM
    J Steroid Biochem Mol Biol; 2011 May; 125(1-2):95-104. PubMed ID: 21087665
    [TBL] [Abstract][Full Text] [Related]  

  • 23. A salicylic acid-based analogue discovered from virtual screening as a potent inhibitor of human 20alpha-hydroxysteroid dehydrogenase.
    Dhagat U; Carbone V; Chung RP; Matsunaga T; Endo S; Hara A; El-Kabbani O
    Med Chem; 2007 Nov; 3(6):546-50. PubMed ID: 18045204
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Stereospecific reduction of 5β-reduced steroids by human ketosteroid reductases of the AKR (aldo-keto reductase) superfamily: role of AKR1C1-AKR1C4 in the metabolism of testosterone and progesterone via the 5β-reductase pathway.
    Jin Y; Mesaros AC; Blair IA; Penning TM
    Biochem J; 2011 Jul; 437(1):53-61. PubMed ID: 21521174
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Human 20α-hydroxysteroid dehydrogenase (AKR1C1)-dependent biotransformation with recombinant fission yeast Schizosaccharomyces pombe.
    Naumann JM; Messinger J; Bureik M
    J Biotechnol; 2010 Oct; 150(1):161-70. PubMed ID: 20727920
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Interleukin 1β regulates progesterone metabolism in human cervical fibroblasts.
    Roberson AE; Hyatt K; Kenkel C; Hanson K; Myers DA
    Reprod Sci; 2012 Mar; 19(3):271-81. PubMed ID: 22064385
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Structure of aldehyde reductase in ternary complex with coenzyme and the potent 20alpha-hydroxysteroid dehydrogenase inhibitor 3,5-dichlorosalicylic acid: implications for inhibitor binding and selectivity.
    Carbone V; Chung R; Endo S; Hara A; El-Kabbani O
    Arch Biochem Biophys; 2008 Nov; 479(1):82-7. PubMed ID: 18782556
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Characterization of hamster NAD+-dependent 3(17)β-hydroxysteroid dehydrogenase belonging to the aldo-keto reductase 1C subfamily.
    Endo S; Noda M; Ikari A; Tatematsu K; El-Kabbani O; Hara A; Kitade Y; Matsunaga T
    J Biochem; 2015 Nov; 158(5):425-34. PubMed ID: 26002966
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma.
    Lewis MJ; Wiebe JP; Heathcote JG
    BMC Cancer; 2004 Jun; 4():27. PubMed ID: 15212687
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Substrate specificity of human 3(20)alpha-hydroxysteroid dehydrogenase for neurosteroids and its inhibition by benzodiazepines.
    Usami N; Yamamoto T; Shintani S; Ishikura S; Higaki Y; Katagiri Y; Hara A
    Biol Pharm Bull; 2002 Apr; 25(4):441-5. PubMed ID: 11995921
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Human 3-alpha hydroxysteroid dehydrogenase type 3 (3α-HSD3): the V54L mutation restricting the steroid alternative binding and enhancing the 20α-HSD activity.
    Zhang B; Zhu DW; Hu XJ; Zhou M; Shang P; Lin SX
    J Steroid Biochem Mol Biol; 2014 May; 141():135-43. PubMed ID: 24434280
    [TBL] [Abstract][Full Text] [Related]  

  • 32. A novel steroid inhibitor for a rat 20alpha-hydroxysteroid dehydrogenase isozyme.
    Yoshida S; Shiota K; Nishihara M; Takahashi M
    Biol Reprod; 1997 Dec; 57(6):1433-7. PubMed ID: 9408251
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Design and development of novel inhibitors of aldo-ketoreductase 1C1 as potential lead molecules in treatment of breast cancer.
    Verma P; Hassan MI; Singh A; Singh IK
    Mol Cell Biochem; 2021 Aug; 476(8):2975-2987. PubMed ID: 33770316
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Human 20alpha-hydroxysteroid dehydrogenase: crystallographic and site-directed mutagenesis studies lead to the identification of an alternative binding site for C21-steroids.
    Couture JF; Legrand P; Cantin L; Luu-The V; Labrie F; Breton R
    J Mol Biol; 2003 Aug; 331(3):593-604. PubMed ID: 12899831
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Progesterone metabolism in adipose cells.
    Zhang Y; Nadeau M; Faucher F; Lescelleur O; Biron S; Daris M; Rhéaume C; Luu-The V; Tchernof A
    Mol Cell Endocrinol; 2009 Jan; 298(1-2):76-83. PubMed ID: 18984031
    [TBL] [Abstract][Full Text] [Related]  

  • 36. New enzymatic assay for the AKR1C enzymes.
    Beranič N; Stefane B; Brus B; Gobec S; Rižner TL
    Chem Biol Interact; 2013 Feb; 202(1-3):204-9. PubMed ID: 23261716
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Human chorionic gonadotropin-dependent induction of an equine aldo-keto reductase (AKR1C23) with 20alpha-hydroxysteroid dehydrogenase activity during follicular luteinization in vivo.
    Brown KA; Boerboom D; Bouchard N; Doré M; Lussier JG; Sirois J
    J Mol Endocrinol; 2006 Jun; 36(3):449-61. PubMed ID: 16720716
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Rabbit 3-hydroxyhexobarbital dehydrogenase is a NADPH-preferring reductase with broad substrate specificity for ketosteroids, prostaglandin D₂, and other endogenous and xenobiotic carbonyl compounds.
    Endo S; Matsunaga T; Matsumoto A; Arai Y; Ohno S; El-Kabbani O; Tajima K; Bunai Y; Yamano S; Hara A; Kitade Y
    Biochem Pharmacol; 2013 Nov; 86(9):1366-75. PubMed ID: 23994167
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Pathophysiological roles of aldo-keto reductases (AKR1C1 and AKR1C3) in development of cisplatin resistance in human colon cancers.
    Matsunaga T; Hojo A; Yamane Y; Endo S; El-Kabbani O; Hara A
    Chem Biol Interact; 2013 Feb; 202(1-3):234-42. PubMed ID: 23165153
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Expression, crystallization and preliminary X-ray analysis of human and rabbit 20alpha-hydroxysteroid dehydrogenases in complex with NADP(H) and various steroid substrates.
    Couture JF; Cantin L; Legrand P; Luu-The V; Labrie F; Breton R
    Acta Crystallogr D Biol Crystallogr; 2002 Jan; 58(Pt 1):135-9. PubMed ID: 11752791
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.