241 related articles for article (PubMed ID: 21051358)
1. hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex.
Richard DJ; Savage K; Bolderson E; Cubeddu L; So S; Ghita M; Chen DJ; White MF; Richard K; Prise KM; Schettino G; Khanna KK
Nucleic Acids Res; 2011 Mar; 39(5):1692-702. PubMed ID: 21051358
[TBL] [Abstract][Full Text] [Related]
2. hSSB1 interacts directly with the MRN complex stimulating its recruitment to DNA double-strand breaks and its endo-nuclease activity.
Richard DJ; Cubeddu L; Urquhart AJ; Bain A; Bolderson E; Menon D; White MF; Khanna KK
Nucleic Acids Res; 2011 May; 39(9):3643-51. PubMed ID: 21227926
[TBL] [Abstract][Full Text] [Related]
3. Deubiquitinase USP2 stabilizes the MRE11-RAD50-NBS1 complex at DNA double-strand break sites by counteracting the ubiquitination of NBS1.
Kim H; Kim D; Choi H; Shin G; Lee JK
J Biol Chem; 2023 Jan; 299(1):102752. PubMed ID: 36436562
[TBL] [Abstract][Full Text] [Related]
4. Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair.
Chen L; Nievera CJ; Lee AY; Wu X
J Biol Chem; 2008 Mar; 283(12):7713-20. PubMed ID: 18171670
[TBL] [Abstract][Full Text] [Related]
5. Rad17 recruits the MRE11-RAD50-NBS1 complex to regulate the cellular response to DNA double-strand breaks.
Wang Q; Goldstein M; Alexander P; Wakeman TP; Sun T; Feng J; Lou Z; Kastan MB; Wang XF
EMBO J; 2014 Apr; 33(8):862-77. PubMed ID: 24534091
[TBL] [Abstract][Full Text] [Related]
6. Stable maintenance of the Mre11-Rad50-Nbs1 complex is sufficient to restore the DNA double-strand break response in cells lacking RecQL4 helicase activity.
Kim H; Choi H; Im JS; Park SY; Shin G; Yoo JH; Kim G; Lee JK
J Biol Chem; 2021 Oct; 297(4):101148. PubMed ID: 34473993
[TBL] [Abstract][Full Text] [Related]
7. Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks.
Langerak P; Mejia-Ramirez E; Limbo O; Russell P
PLoS Genet; 2011 Sep; 7(9):e1002271. PubMed ID: 21931565
[TBL] [Abstract][Full Text] [Related]
8. MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks.
Helmink BA; Bredemeyer AL; Lee BS; Huang CY; Sharma GG; Walker LM; Bednarski JJ; Lee WL; Pandita TK; Bassing CH; Sleckman BP
J Exp Med; 2009 Mar; 206(3):669-79. PubMed ID: 19221393
[TBL] [Abstract][Full Text] [Related]
9. The molecular details of a novel phosphorylation-dependent interaction between MRN and the SOSS complex.
El-Kamand S; Adams MN; Matthews JM; Du Plessis MD; Crossett B; Connolly A; Breen N; Dudley A; Richard DJ; Gamsjaeger R; Cubeddu L
Protein Sci; 2023 Oct; 32(10):e4782. PubMed ID: 37705456
[TBL] [Abstract][Full Text] [Related]
10. Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity.
Jazayeri A; Balestrini A; Garner E; Haber JE; Costanzo V
EMBO J; 2008 Jul; 27(14):1953-62. PubMed ID: 18596698
[TBL] [Abstract][Full Text] [Related]
11. Rad50 zinc hook is important for the Mre11 complex to bind chromosomal DNA double-stranded breaks and initiate various DNA damage responses.
He J; Shi LZ; Truong LN; Lu CS; Razavian N; Li Y; Negrete A; Shiloach J; Berns MW; Wu X
J Biol Chem; 2012 Sep; 287(38):31747-56. PubMed ID: 22833675
[TBL] [Abstract][Full Text] [Related]
12. MRNIP condensates promote DNA double-strand break sensing and end resection.
Wang YL; Zhao WW; Bai SM; Feng LL; Bie SY; Gong L; Wang F; Wei MB; Feng WX; Pang XL; Qin CL; Yin XK; Wang YN; Zhou W; Wahl DR; Liu Q; Chen M; Hung MC; Wan XB
Nat Commun; 2022 May; 13(1):2638. PubMed ID: 35551189
[TBL] [Abstract][Full Text] [Related]
13. MRE11 complex links RECQ5 helicase to sites of DNA damage.
Zheng L; Kanagaraj R; Mihaljevic B; Schwendener S; Sartori AA; Gerrits B; Shevelev I; Janscak P
Nucleic Acids Res; 2009 May; 37(8):2645-57. PubMed ID: 19270065
[TBL] [Abstract][Full Text] [Related]
14. The role of the Mre11-Rad50-Nbs1 complex in double-strand break repair-facts and myths.
Takeda S; Hoa NN; Sasanuma H
J Radiat Res; 2016 Aug; 57 Suppl 1(Suppl 1):i25-i32. PubMed ID: 27311583
[TBL] [Abstract][Full Text] [Related]
15. Smad7 enhances ATM activity by facilitating the interaction between ATM and Mre11-Rad50-Nbs1 complex in DNA double-strand break repair.
Park S; Kang JM; Kim SJ; Kim H; Hong S; Lee YJ; Kim SJ
Cell Mol Life Sci; 2015 Feb; 72(3):583-596. PubMed ID: 25063542
[TBL] [Abstract][Full Text] [Related]
16. N terminus of CtIP is critical for homologous recombination-mediated double-strand break repair.
Yuan J; Chen J
J Biol Chem; 2009 Nov; 284(46):31746-52. PubMed ID: 19759395
[TBL] [Abstract][Full Text] [Related]
17. MRN-dependent and independent pathways for recruitment of TOPBP1 to DNA double-strand breaks.
Montales K; Ruis K; Lindsay H; Michael WM
PLoS One; 2022; 17(8):e0271905. PubMed ID: 35917319
[TBL] [Abstract][Full Text] [Related]
18. Sp1 facilitates DNA double-strand break repair through a nontranscriptional mechanism.
Beishline K; Kelly CM; Olofsson BA; Koduri S; Emrich J; Greenberg RA; Azizkhan-Clifford J
Mol Cell Biol; 2012 Sep; 32(18):3790-9. PubMed ID: 22826432
[TBL] [Abstract][Full Text] [Related]
19. Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.
Williams RS; Williams JS; Tainer JA
Biochem Cell Biol; 2007 Aug; 85(4):509-20. PubMed ID: 17713585
[TBL] [Abstract][Full Text] [Related]
20. MRE11-RAD50-NBS1 Complex Is Sufficient to Promote Transcription by RNA Polymerase II at Double-Strand Breaks by Melting DNA Ends.
Sharma S; Anand R; Zhang X; Francia S; Michelini F; Galbiati A; Williams H; Ronato DA; Masson JY; Rothenberg E; Cejka P; d'Adda di Fagagna F
Cell Rep; 2021 Jan; 34(1):108565. PubMed ID: 33406426
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
